Co-infections with hepatitis B and C viruses in human immunodeficiency virus-infected patients in Morocco

Co-infections with hepatitis B and C viruses in human immunodeficiency virus-infected patients in Morocco

Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis Cvirus (HCV) are major public health concerns. We aimed to determine the prevalence of HBV and HCV infections among HIV-infected patients, and to identify the main circulating hepatitis strains in Morocco. The study was carrie...

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Bibliographic Details
Published in:Clinical microbiology and infection Vol. 19; no. 10; pp. E454 - E457
Main Authors: Rebbani, K., Ouladlahsen, A., Bensghir, A., Akil, A., Lamdini, H., Issouf, H., Brahim, I., Kitab, B., Fakhir, F.Z., Wakrim, L., Marhoum El Filali, K., Himmich, H., Ezzikouri, S., Benjelloun, S.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-10-2013
Elsevier Limited
Subjects:
Adult
Antigens
Chronic hepatitis
co-infection
Coinfection - epidemiology
Coinfection - virology
DNA
Drug therapy
Female
genotype
Hepatitis
Hepatitis B - epidemiology
Hepatitis B - virology
Hepatitis B virus
Hepatitis C - epidemiology
Hepatitis C - virology
HIV
Human immunodeficiency virus
Humans
Male
Middle Aged
Morocco - epidemiology
prevalence
Morocco
human immunodeficiency virus
prevalence
co-infection
Chronic hepatitis
genotype
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Summary:Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis Cvirus (HCV) are major public health concerns. We aimed to determine the prevalence of HBV and HCV infections among HIV-infected patients, and to identify the main circulating hepatitis strains in Morocco. The study was carried out in 503 HIV-infected patients. Our survey indicated that the prevalence of HIV/hepatitis co-infection was 10.6%; 5.2% of patients were HBV surface antigen positive, and 5.4% of patients were anti-HCV positive. Among the HBV surface antigen-positive group, HBV DNA sequencing identified exclusively genotype D (D1: 26.7%; D7: 73.3%) in accordance with what is found in the general population. In contrast, sequencing of HCV isolates produced an unusual subtype distribution with a decreasing order of prevalence: 1a, 3a (both 23.5%), 1b, 4a (both 17.6%), 1c (11.8%) and 6h (6%).
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ISSN:1198-743X
1469-0691
DOI:10.1111/1469-0691.12252