Search Results - "Fajkus, Jiří"
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The rDNA Loci-Intersections of Replication, Transcription, and Repair Pathways
Published in International journal of molecular sciences (28-01-2021)“…Genes encoding ribosomal RNA (rDNA) are essential for cell survival and are particularly sensitive to factors leading to genomic instability. Their repetitive…”
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2
WALTER: an easy way to online evaluate telomere lengths from terminal restriction fragment analysis
Published in BMC bioinformatics (22-03-2021)“…Telomeres, nucleoprotein structures comprising short tandem repeats and delimiting the ends of linear eukaryotic chromosomes, play an important role in the…”
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3
G4 Structures in Control of Replication and Transcription of rRNA Genes
Published in Frontiers in plant science (08-10-2020)“…Genes encoding 45S ribosomal RNA (rDNA) are known for their abundance within eukaryotic genomes and for their unstable copy numbers in response to changes in…”
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4
Extraordinary diversity of telomeres, telomerase RNAs and their template regions in Saccharomycetaceae
Published in Scientific reports (17-06-2021)“…Telomerase RNA (TR) carries the template for synthesis of telomere DNA and provides a scaffold for telomerase assembly. Fungal TRs are long and have been…”
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5
Chromatin, Epigenetics and Plant Physiology
Published in International journal of molecular sciences (16-04-2020)“…The ever-increasing interest in epigenetics comes from the fact that in the diverse life situations of organisms, e [...]…”
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6
Composition and Function of Telomerase-A Polymerase Associated with the Origin of Eukaryotes
Published in Biomolecules (Basel, Switzerland) (08-10-2020)“…The canonical DNA polymerases involved in the replication of the genome are unable to fully replicate the physical ends of linear chromosomes, called…”
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7
Comparative Dissection of Three Giant Genomes: Allium cepa , Allium sativum , and Allium ursinum
Published in International journal of molecular sciences (09-02-2019)“…Knowledge of the fascinating world of DNA repeats is continuously being enriched by newly identified elements and their hypothetical or well-established…”
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8
Identification of Nucleolus-Associated Chromatin Domains Reveals a Role for the Nucleolus in 3D Organization of the A. thaliana Genome
Published in Cell reports (Cambridge) (09-08-2016)“…The nucleolus is the site of rRNA gene transcription, rRNA processing, and ribosome biogenesis. However, the nucleolus also plays additional roles in the cell…”
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9
Origin and Fates of TERT Gene Copies in Polyploid Plants
Published in International journal of molecular sciences (11-02-2021)“…The gene coding for the telomerase reverse transcriptase ( ) is essential for the maintenance of telomeres. Previously we described the presence of three…”
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Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA
Published in Biochimica et biophysica acta. General subjects (01-09-2020)“…The i-motif is a tetrameric DNA structure based on the formation of hemiprotonated cytosine-cytosine (C+.C) base pairs. i-motifs are widely used in…”
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11
Visualization of the Nucleolus Using Ethynyl Uridine
Published in Frontiers in plant science (16-02-2018)“…Thanks to recent innovative methodologies, key cellular processes such as replication or transcription can be visualized directly in intact tissues. Many…”
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12
Distinct Responses of Arabidopsis Telomeres and Transposable Elements to Zebularine Exposure
Published in International journal of molecular sciences (05-01-2021)“…Involvement of epigenetic mechanisms in the regulation of telomeres and transposable elements (TEs), genomic regions with the protective and potentially…”
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13
Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
Published in Cell reports (Cambridge) (29-08-2023)“…While the pivotal role of linker histone H1 in shaping nucleosome organization is well established, its functional interplays with chromatin factors along the…”
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14
Roles of RAD51 and RTEL1 in telomere and rDNA stability in Physcomitrella patens
Published in The Plant journal : for cell and molecular biology (01-06-2019)“…Summary Telomeres and ribosomal RNA genes (rDNA) are essential for cell survival and particularly sensitive to factors affecting genome stability. Here, we…”
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15
Telomeres in Plants and Humans: Not So Different, Not So Similar
Published in Cells (Basel, Switzerland) (16-01-2019)“…Parallel research on multiple model organisms shows that while some principles of telomere biology are conserved among all eukaryotic kingdoms, we also find…”
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16
Telomere elongation upon transfer to callus culture reflects the reprogramming of telomere stability control in Arabidopsis
Published in Plant molecular biology (01-09-2018)“…Key message Standard pathways involved in the regulation of telomere stability do not contribute to gradual telomere elongation observed in the course of A…”
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17
High-Throughput Non-destructive Phenotyping of Traits that Contribute to Salinity Tolerance in Arabidopsis thaliana
Published in Frontiers in plant science (28-09-2016)“…Reproducible and efficient high-throughput phenotyping approaches, combined with advances in genome sequencing, are facilitating the discovery of genes…”
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18
Different Modes of Action of Genetic and Chemical Downregulation of Histone Deacetylases with Respect to Plant Development and Histone Modifications
Published in International journal of molecular sciences (14-10-2019)“…A high degree of developmental plasticity enables plants to adapt to continuous, often unfavorable and unpredictable changes in their environment. At the…”
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Optimizing ChIRP-MS for Comprehensive Profiling of RNA-Protein Interactions in Arabidopsis thaliana : A Telomerase RNA Case Study
Published in Plants (Basel) (15-03-2024)“…The current repertoire of methods available for studying RNA-protein interactions in plants is somewhat limited. Employing an RNA-centric approach,…”
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Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides
Published in Ecology and evolution (01-07-2021)“…Altered copy number of certain highly repetitive regions of the genome, such as satellite DNA within heterochromatin and ribosomal RNA loci (rDNA), is…”
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