The Emerging Applications of Nanotechnology in Neuroimaging: A Comprehensive Review
Neuroimaging modalities such as computer tomography and magnetic resonance imaging have greatly improved in their ability to achieve higher spatial resolution of neurovascular and soft tissue neuroanatomy, allowing for increased accuracy in the diagnosis of neurological conditions. However, the use...
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| Published in: | Frontiers in bioengineering and biotechnology Vol. 10; p. 855195 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Frontiers Media S.A
06-07-2022
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Neuroimaging modalities such as computer tomography and magnetic resonance imaging have greatly improved in their ability to achieve higher spatial resolution of neurovascular and soft tissue neuroanatomy, allowing for increased accuracy in the diagnosis of neurological conditions. However, the use of conventional contrast agents that have short tissue retention time and associated renal toxicities, or expensive radioisotope tracers that are not widely available, continue to limit the sensitivity of these imaging modalities. Nanoparticles can potentially address these shortcomings by enhancing tissue retention and improving signal intensity in the brain and neural axis. In this review, we discuss the use of different types of nanotechnology to improve the detection, diagnosis, and treatment of a wide range of neurological diseases. |
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| Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 This article was submitted to Nanobiotechnology, a section of the journal Frontiers in Bioengineering and Biotechnology These authors have contributed equally to this work Edited by: Qingxin Mu, University of Washington, United States Jacopo Annese, The Institute for Brain and Society, United States Reviewed by: Leopoldo Sitia, University of Milan, Italy |
| ISSN: | 2296-4185 2296-4185 |
| DOI: | 10.3389/fbioe.2022.855195 |