Search Results - "Fairman, J. W."

Structural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae by Teakel, S. L., Fairman, J. W., Muruthi, M. M., Abendroth, J., Dranow, D. M., Lorimer, D. D., Myler, P. J., Edwards, T. E., Forwood, J. K.

“…Gonorrhoea infection rates and the risk of infection from opportunistic pathogens including P. aeruginosa have both risen globally, in part due to increasing…”
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Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization by Dealwis, Chris Godfrey, Fairman, James Wesley, Wijerathna, Sanath Ranjan, Ahmad, Md Faiz, Xu, Hai, Nakano, Ryo, Jha, Shalini, Prendergast, Jay, Welin, R Martin, Flodin, Susanne, Roos, Annette, Nordlund, Pär, Li, Zongli, Walz, Thomas

“…Ribonucleotide reductase is essential to maintain the cellular pools of dNTPs, and its activity is controlled allosterically by ATP (activator) and dATP…”
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Structures of Eukaryotic Ribonucleotide Reductase I Provide Insights into dNTP Regulation by Xu, Hai, Faber, Catherine, Uchiki, Tomoaki, Fairman, James W., Racca, Joseph, Dealwis, Chris

“…Ribonucleotide reductase catalyzes a crucial step in de novo DNA synthesis and is allosterically controlled by relative levels of dNTPs to maintain a balanced…”
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