Search Results - "Fairclough, P D"

Repeated colonoscopic screening of patients with acromegaly: 15-year experience identifies those at risk of new colonic neoplasia and allows for effective screening guidelines by Dworakowska, D, Gueorguiev, M, Kelly, P, Monson, J P, Besser, G M, Chew, S L, Akker, S A, Drake, W M, Fairclough, P D, Grossman, A B, Jenkins, P J

“…ObjectiveIt is suggested that patients with acromegaly have an increased risk of colorectal cancer and pre-malignant adenomatous polyps. However, the optimum…”
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Endoscopic ultrasound in the localisation of pancreatic islet cell tumours by McLean, A.M., Fairclough, P.D.

“…The role of endoscopic ultrasound (EUS) in the evaluation of entero-pancreatic endocrine tumours has evolved in conjunction with advances in other imaging…”
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Insulin-like growth factor I and the development of colorectal neoplasia in acromegaly by JENKINS, P. J, FRAJESE, V, JONES, A-M, CAMACHO-HUBNER, C, LOWE, D. G, FAIRCLOUGH, P. D, CHEW, S. L, GROSSMAN, A. B, MONSON, J. P, BESSER, G. M

“…Patients with acromegaly are at increased risk of colorectal neoplasia and, by analogy with high-risk nonacromegalic patients, may require regular colonoscopic…”
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Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002) by Cairns, Stuart R, Scholefield, John H, Steele, Robert J, Dunlop, Malcolm G, Thomas, Huw J W, Evans, Gareth D, Eaden, Jayne A, Rutter, Matthew D, Atkin, Wendy P, Saunders, Brian P, Lucassen, Anneke, Jenkins, Paul, Fairclough, Peter D, Woodhouse, Christopher R J

“…The British Society of Gastroenterology (BSG) and the Association of Coloproctology for Great Britain and Ireland (ACPGBI) commissioned this update of the 2002…”
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Selective COX‐2 inhibitors and human inflammatory bowel disease by MCCARTNEY, S. A, MITCHELL, J. A, FAIRCLOUGH, P. D, FARTHING, M. J. G, WARNER, T. D

“…Background : Much recent effort has been made to produce selective inhibitors of cyclo‐oxygenase‐2 (COX‐2) in the belief that these will lack the…”
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Screening guidelines for colorectal cancer and polyps in patients with acromegaly by Jenkins, P J, Fairclough, P D

“…There are approximately 2500 patients with acromegaly in the UK. Because of the complexity of the disease and its treatment, tertiary referral centres manage…”
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Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts by Bajaj-Elliott, M, Breese, E, Poulsom, R, Fairclough, PD, MacDonald, TT

“…Inflammation in the gastrointestinal tract is associated with increased epithelial cell proliferation. Keratinocyte growth factor (KGF) is an epithelial cell…”
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Factors Associated with Tolerance to, and Discomfort with, Unsedated Diagnostic Gastroscopy by MULCAHY, H. E, KELLY, P, BANKS, M. R, CONNOR, P, PATCHET, S. E, FARTHING, M. J. G, FAIRCLOUGH, P. D, KUMAR, P. J

“…Background: Identification of patients likely to experience high levels of discomfort during unsedated gastroscopy would be useful as these patients could be…”
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A prospective controlled trial of an ultrathin versus a conventional endoscope in unsedated upper gastrointestinal endoscopy by Mulcahy, H E, Riches, A, Kiely, M, Farthing, M J, Fairclough, P D

“…Upper gastrointestinal endoscopy is performed without sedation in many countries. Unsedated patients experience more discomfort during endoscopy than sedated…”
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Human Peyer's Patch T Cells Are Sensitized to Dietary Antigen and Display a Th Cell Type 1 Cytokine Profile by Nagata, Satoru, McKenzie, Catriona, Pender, Sylvia L. F, Bajaj-Elliott, Mona, Fairclough, Peter D, Walker-Smith, John A, Monteleone, Giovanni, MacDonald, Thomas T

“…Animal studies have demonstrated that feeding Ags induces regulatory (Th2, Th3) cells in Peyer's patches (PP), which migrate to the periphery and produce…”
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Acromegaly, colonic polyps and carcinoma by Jenkins, Paul J., Fairclough, Peter D., Richards, Toby, Lowe, David G., Monson, John, Grossman, Ashley, Wass, John A. H., Besser, Michael

“…OBJECTIVE It has been suggested that patients with acromegaly may be at risk of developing colorectal carcinoma. In order to clarify this issue, we have…”
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Changing patterns of sedation use for routine out‐patient diagnostic gastroscopy between 1989 and 1998 by Mulcahy, H. E., Hennessy, E., Connor, P., Rhodes, B., Patchett, S. E., Farthing, M. J. G., Fairclough, P. D.

“…Background: Knowledge of sedation trends for upper gastrointestinal endoscopy is important for health service planning, particularly in view of rapidly…”
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Erythromycin and the gut by Catnach, S M, Fairclough, P D

“…The commonly reported gastrointestinal side effects that occur with erythromycin are related to its prokinetic action on the gut, mediated, at least in part,…”
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Expression of 25-hydroxyvitamin D-1-α-hydroxylase mRNA in individuals with colorectal cancer by Ogunkolade, BW, Boucher, BJ, Fairclough, PD, Hitman, GA, Dorudi, S, Jenkins, PJ, Bustin, SA

“…Vitamin D prevents proliferation, promotes differentiation, and induces apoptosis of colon cells, and reduced intake or insufficiency of the vitamin in the…”
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Pancolonic spatiotemporal mapping reveals regional deficiencies in, and disorganization of colonic propagating pressure waves in severe constipation by Dinning, P. G., Zarate, N., Hunt, L. M., Fuentealba, S. E., Mohammed, S. D., Szczesniak, M. M., Lubowski, D. Z., Preston, S. L., Fairclough, P. D., Lunniss, P. J., Scott, S. M., Cook, I. J.

“…Background  The morphology, motor responses and spatiotemporal organization among colonic propagating sequences (PS) have never been defined throughout the…”
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Ultrathin endoscopy in the assessment and treatment of upper and lower gastrointestinal tract strictures by Mulcahy, Hugh E., Fairclough, Peter D.

“…Background: Ultrathin (≤ 6 mm diameter) endoscopes have recently been introduced into clinical practice. Methods: We retrospectively assessed the role of a 6…”
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Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly by Miraki-Moud, F., Jenkins, P. J., Fairclough, P. D., Jordan, S., Bustin, S. A., Jones, A. M., Lowe, D. G., Monson, J. P., Grossman, A. B., Besser, G. M., Camacho-Hübner, C.

“…OBJECTIVE Patients with acromegaly are at increased risk of developing colorectal carcinoma and premalignant tubulovillous adenoma. The pathogenesis of these…”
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Is intervention necessary after a first episode of acute idiopathic pancreatitis? by Ballinger, A B, Barnes, E, Alstead, E M, Fairclough, P D

“…Acute idiopathic pancreatitis is a term used when no underlying cause has been identified on routine investigation. However, more specialised investigations…”
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Interchange between collagenous and lymphocytic colitis in severe disease with autoimmune associations requiring colectomy: a case report by Bowling, T E, Price, A B, al-Adnani, M, Fairclough, P D, Menzies-Gow, N, Silk, D B

“…BACKGROUND--Collagenous colitis and lymphocytic colitis present with a similar clinical picture. Whether these conditions are separate entities or whether they…”
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Effective palliation of a colovaginal fistula using a self-expanding metal stent by Jeyarajah, Arjun R., Shepherd, John H., Fairclough, Peter D., Patchett, Stephen E.

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