Search Results - "Fairbanks, Michael B."
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Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer
Published in The Journal of biological chemistry (15-10-1999)“…Human platelet heparanase has been purified to homogeneity and shown to consist of two, non-covalently associated polypeptide chains of molecular masses 50 and…”
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Cation binding to the integrin CD11b I domain and activation model assessment
Published in Structure (London) (15-07-1998)“…Background: The integrin family of cell-surface receptors mediate cell adhesion through interactions with the extracellular matrix or other cell-surface…”
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Alzheimer's disease and control brain contain soluble derivatives of the amyloid protein precursor that end within the .beta. amyloid protein region
Published in Biochemistry (Easton) (10-11-1992)“…The 39-43 amino acid beta amyloid protein (A beta) that deposits as amyloid in the brains of patients with Alzheimer's disease (AD) is encoded as an internal…”
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Cleaved high molecular weight kininogen binds directly to the integrin CD11b/CD18 (Mac-1) and blocks adhesion to fibrinogen and ICAM-1
Published in Blood (15-06-2000)“…High molecular weight kininogen (HK) and its cleaved form (HKa) have been shown to bind to neutrophils. Based on studies using monoclonal antibodies (mAbs), we…”
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Cleaved high molecular weight kininogen binds directly to the integrin CD11b/CD18 (Mac-1) and blocks adhesion to fibrinogen and ICAM-1
Published in Blood (15-06-2000)“…High molecular weight kininogen (HK) and its cleaved form (HKa) have been shown to bind to neutrophils. Based on studies using monoclonal antibodies (mAbs), we…”
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Alzheimer's amyloid precursor protein produced by recombinant baculovirus expression. Proteolytic processing and protease inhibitory properties
Published in The Journal of biological chemistry (15-10-1991)“…The baculovirus expression system was used to generate recombinant Alzheimer's amyloid precursor (AAP) proteins. Recombinant baculoviruses were constructed,…”
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Purification and structural characterization of the CD11b/CD18 integrin α subunit I domain reveals a folded conformation in solution
Published in FEBS letters (07-08-1995)“…The α subunits of the leukocyte CD11/CD18 integrins contain a ∼200 amino acid ‘inserted’ or I domain. The I domain of the cell-surface Mac-1(CD11b/CD18)…”
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The dependence of the oxygen-concentrating mechanism of the teleost eye (Salmo gairdneri) on the enzyme carbonic anhydrase
Published in The Journal of general physiology (01-08-1969)“…Microoxygen polarographic electrodes were constructed and used to measure oxygen tension (P(OO2)) in the eyes of rainbow trout (Salmo gairdneri). The values…”
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Short circuiting the ocular oxygen concentrating mechanism in the teleost Salmo gairdneri using carbonic anhydrase inhibitors
Published in The Journal of general physiology (01-09-1974)“…Ocular oxygen concentration by the process of counter current multiplication in rainbow trout (Salmo gairdneri) was rapidly suppressed after intraperitoneal…”
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