Search Results - "Failla, M.L"

Metabolomics in the opening decade of the 21st century: building the roads to individualized health by German, J B, Bauman, D E, Burrin, D G, Failla, M L, Freake, H C, King, J C, Klein, S, Milner, J A, Pelto, G H, Rasmussen, K M, Zeisel, S H

“…It is rapidly becoming possible to measure hundreds or thousands of metabolites in small samples of biological fluids or tissues. This makes it possible to…”
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Carotenoid Composition in 'Ataulfo' Mango and Their Bioavailability and Bioconversion to Vitamin A by Ornelas-Paz, J. de J, Gardea, A.A, Yahia, E.M, Failla, M.L

“…'Ataulfo' mango (Mangifera indica L.) is one of the most produced and consumed fruits in Mexico. This mango cultivar is claimed as a good source of…”
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Impact of Fatty Acyl Composition and Quantity of Triglycerides on Bioaccessibility of Dietary Carotenoids by Huo, Tianyao, Ferruzzi, Mario G, Schwartz, Steven J, Failla, Mark L

“…A carotenoid-rich salad meal with varying amounts and types of triglycerides (TG) was digested using simulated gastric and small intestinal conditions…”
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Assessment of lutein bioavailability from meals and a supplement using simulated digestion and caco-2 human intestinal cells by Chitchumroonchokchai, Chureeporn, Schwartz, Steven J, Failla, Mark L

“…Lutein and zeaxanthin are selectively accumulated in the lens and macular region of the retina. It was suggested that these xanthophylls protect ocular tissues…”
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Impact of the Stage of Ripening and Dietary Fat on in Vitro Bioaccessibility of β-Carotene in ‘Ataulfo’ Mango by Ornelas-Paz, J. De Jesus, Failla, Mark L, Yahia, Elhadi M, Gardea-Bejar, Alfonso

“…Pulp from “slightly ripe”, “moderately ripe”, or “fully ripe” mangoes was digested in vitro in the absence and presence of processed chicken as a source of…”
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Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells by Chitchumroonchokchai, Chureeporn, Bomser, Joshua A, Glamm, Jayme E, Failla, Mark L

“…Epidemiological studies suggest that consumption of vegetables rich in the xanthophylls lutein (LUT) and zeaxanthin (ZEA) reduces the risk for developing…”
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Supplementation of Test Meals with Fat-Free Phytosterol Products Can Reduce Cholesterol Micellarization during Simulated Digestion and Cholesterol Accumulation by Caco-2 Cells by Bohn, Torsten, Tian, Qingguo, Chitchumroonchokchai, Chureeporn, Failla, Mark L, Schwartz, Steven J, Cotter, Richard, Waksman, Joel A

“…Phytosterols have been shown to reduce cholesterol absorption in humans. Supplementing phytosterols in fat-free formulations, however, has yielded…”
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Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage by Martin, K R, Failla, M L, Smith, Jr, J C

“…Numerous epidemiological studies support a strong inverse relationship between consumption of carotenoid-rich fruits and vegetables and the incidence of some…”
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Reduction of Fe(III) is required for uptake of nonheme iron by Caco-2 cells by Han, O, Failla, M L, Hill, A D, Morris, E R, Smith, Jr, J C

“…Differentiated cultures of Caco-2 human colonic cells were used to examine the importance of reduction of nonheme ferric iron, Fe(III), for transport across…”
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Copper deficiency reduces interleukin-2 (IL-2) production and IL-2 mRNA in human T-lymphocytes by Hopkins, R G, Failla, M L

“…Although dietary copper (Cu) deficiency has been associated with decreased production of interleukin-2 (IL-2) by activated splenic mononuclear cells in rodent…”
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Nutrition: a reservoir for integrative science by Zeisel, S H, Allen, L H, Coburn, S P, Erdman, J W, Failla, M L, Freake, H C, King, J C, Storch, J

“…In the last twenty years, powerful new molecular techniques were introduced that made it possible to advance knowledge in human biology using a reductionist…”
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Is low copper status immunosuppressive? by Failla, M.L. (University of North Carolina, Greensboro.), Hopkins, R.G

“…Recent studies indicate that the micronutrient copper is required for the normal development and function of cells in the innate and acquired arms of the…”
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Respiratory burst and candidacidal activity of peritoneal macrophages are impaired in copper-deficient rats by Babu, U, Failla, M L

“…To investigate the effect of dietary copper deficiency on the function of peritoneal macrophages, weaned male Lewis rats were pair-fed diets containing either…”
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Marginal copper-restricted diets produce altered cardiac ultrastructure in the rat by Wildman, R E, Hopkins, R, Failla, M L, Medeiros, D M

“…To determine if chronic ingestion of a diet containing a marginally low level of Cu could cause deleterious alterations in cardiac ultrastructure, male…”
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Copper repletion restores the number and function of CD4 cells in copper-deficient rats by Bala, S, Failla, M L

“…Dietary copper deficiency decreases the number of splenic CD4 cells and mitogen-induced generation of interleukin-2 activity and DNA synthesis in cultures of…”
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Copper status and function of neutrophils are reversibly depressed in marginally and severely copper-deficient rats by Babu, U, Failla, M L

“…Weaned male rats were pair-fed diets containing either adequate (7 mg/kg diet; +Cu) or deficient (0.7 mg/kg diet; -Cu) levels of copper for 5 wk. Cellular Cu…”
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Ascorbate offsets the inhibitory effect of inositol phosphates on iron uptake and transport by Caco-2 cells by Han, O, Failla, M L, Hill, A D, Morris, E R, Smith, Jr, J C

“…Differentiated monolayer cultures of Caco-2 human intestinal cells were used as a model to examine interactions between various dietary factors related to the…”
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Alterations in splenic lymphoid cell subsets and activation antigens in copper-deficient rats by Bala, S, Failla, M L, Lunney, J K

“…Rats were nursed by dams fed a diet containing adequate (6 micrograms/g) or deficient (0.6 micrograms/g) Cu during the lactation period and weaned to the same…”
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Differential up-regulation of ceruloplasmin gene expression in rat immune tissues during experimental inflammation by Pan, Yuanlong, Failla, Mark L.

“…We have investigated whether rat immune tissues (spleen, thymus and bone marrow) contain a full-length ceruloplasmin (Cp) mRNA identical to that in rat…”
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Copper deficiency reversibly impairs DNA synthesis inactivated T lymphocytes by limiting interleukin 2 activity by Bala, S. (Food and Drug Administration, Rockville, MD), Failla, M.L

“…The essentiality of adequate copper (Cu) nutriture for normal T-cell function in laboratory and domestic animals is well established. However, specific…”
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