Search Results - "Fai Kwok, Ching"
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Exercise reduces body fat and improves insulin sensitivity and pancreatic β-cell function in overweight and obese male Taiwanese adolescents
Published in BMC pediatrics (22-02-2018)“…Improvements in insulin resistance and pancreatic β-cell function have been shown following exercise in adults with obesity; however, few adolescent-based…”
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Using proteomics to discover novel biomarkers for fatty liver development and response to CB1R antagonist treatment in an obese mouse model
Published in Proteomics (Weinheim) (01-01-2017)“…Over activity of cannabinoid receptor type 1 (CB1R) plays a key role in increasing the incidence of obesity‐induced non‐alcoholic fatty liver disease. Tissue…”
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Cannabinoid receptor type 1 mediates high-fat diet-induced insulin resistance by increasing forkhead box O1 activity in a mouse model of obesity
Published in International journal of molecular medicine (01-03-2016)“…Hepatic glucose production is promoted by forkhead box O1 (FoxO1) under conditions of insulin resistance. The overactivity of cannabinoid receptor type 1…”
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Chronic endothelin‐1 infusion causes adipocyte hyperplasia in rats
Published in Obesity (Silver Spring, Md.) (01-03-2016)“…Objective The aim of this study was to investigate the regulatory mechanism of endothelin‐1 (ET‐1), an endothelium‐derived vasoconstrictor, on adipogenesis in…”
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Insulin Up-Regulates Heme Oxygenase-1 Expression in 3T3-L1 Adipocytes via PI3-Kinase- and PKC-Dependent Pathways and Heme Oxygenase-1–Associated MicroRNA Downregulation
Published in Endocrinology (Philadelphia) (01-02-2011)“…Insulin has a stimulatory effect on heme oxygenase-1 expression in 3T3-L1 adipocytes. Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has…”
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Acarbose plus metformin fixed-dose combination outperforms acarbose monotherapy for type 2 diabetes
Published in Diabetes research and clinical practice (01-10-2013)“…Abstract Aim To compare the efficacy and safety of acarbose plus metformin fixed-dose combination (FDC) versus acarbose monotherapy for type 2 diabetes (T2D)…”
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The Combination of the Ankle Brachial Index and Brachial Ankle Pulse Wave Velocity Exhibits a Superior Association with Outcomes in Diabetic Patients
Published in Internal Medicine (01-01-2014)“…Objective Patients with type 2 diabetes mellitus (T2DM) and peripheral arterial disease are classified as having very high cardiovascular risks. We therefore…”
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Look Action for Health in Diabetes trial: What we have learned in terms of real world practice and clinical trials
Published in Journal of diabetes investigation (01-11-2014)“…[...]the increased use of statins in the DSE group might have lessened the difference in CVD rates between the two groups, probably by decreasing the blood…”
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Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting
Published in World journal of gastroenterology : WJG (28-07-2006)“…AIM: To isolate putative pancreatic stem cells (PSCs) from human adult tissues of pancreas duct using serumfree, conditioned medium. The characterization of…”
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Whether to report diabetes as the underlying cause-of-death? a survey of internists of different sub-specialties
Published in BMC endocrine disorders (23-07-2010)“…Cause-specific mortality is a commonly used endpoint of clinical trials or prospective studies. However, it is sometimes difficult for physician to determine…”
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Severe hypoglycemia predicts major adverse outcomes in diabetic patients undergoing glycemic control regimes
Published in Journal of diabetes investigation (01-02-2012)Get full text
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12
Angiotensin II Enhances Insulin Sensitivity in Vitro and in Vivo
Published in Endocrinology (Philadelphia) (01-05-2005)“…The renin-angiotensin system plays a critical role in the pathogenesis of obesity, obesity-associated hypertension, and insulin resistance. However, the…”
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Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor
Published in Biochemical and biophysical research communications (22-08-2014)“…•Ang II enhances ET-1-induced vasoconstriction in endothelium-denuded aorta.•Ang II upregulates the expression of ETAR and binding capacity of ET-1 in…”
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Resistin induces monocyte-endothelial cell adhesion by increasing ICAM-1 and VCAM-1 expression in endothelial cells via p38MAPK-dependent pathway
Published in Journal of cellular physiology (01-08-2011)“…Resistin, firstly reported as an adipocyte‐specific hormone, is suggested to be an important link between obesity and diabetes. Recent studies have suggested…”
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Visfatin Promotes Monocyte Adhesion by Upregulating ICAM-1 and VCAM-1 Expression in Endothelial Cells via Activation of p38-PI3K-Akt Signaling and Subsequent ROS Production and IKK/NF-κB Activation
Published in Cellular physiology and biochemistry (2019)“…Visfatin is known to act as a mediator in several metabolic disorders, such as obesity, diabetes, and cardiovascular diseases. This study aimed to investigate…”
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VISFATIN PROMOTES FOAM CELL FORMATION BY DYSREGULATING CD36, SRA, ABCA1, AND ABCG1 EXPRESSION IN RAW264.7 MACROPHAGES
Published in Shock (Augusta, Ga.) (01-04-2016)“…BACKGROUND:Visfatin is produced in and secreted from adipocytes. Increased circulating visfatin level is observed in obese subjects. Previous studies…”
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Diffuse soft tissue emphysema in anorexia nervosa: A case report
Published in The International journal of eating disorders (01-11-2005)“…Objective: Anorexia nervosa (AN) is an eating disorder that occurs mainly among young females and its prevalence has increased in recent decades. Methods: We…”
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Effects of bariatric weight loss surgery on glucose metabolism, inflammatory cytokines, and serum tartrate-resistant acid phosphatase 5a in obese Chinese adults
Published in Clinica chimica acta (30-01-2016)“…We determined effects of bariatric weight loss surgery on serum tartrate-resistant acid phosphatase 5a (TRACP 5a), inflammatory cytokines and glucose…”
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Endothelin-1 exacerbates development of hypertension and atherosclerosis in modest insulin resistant syndrome
Published in Biochemical and biophysical research communications (08-05-2015)“…Endothelin-1 (ET-1) is known as potent vasoconstrictor, by virtue of its mitogenic effects, and may deteriorate the process of hypertension and atherosclerosis…”
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Major urinary protein 1 interacts with cannabinoid receptor type 1 in fatty acid-induced hepatic insulin resistance in a mouse hepatocyte model
Published in Biochemical and biophysical research communications (15-05-2015)“…Hepatic insulin resistance (HIR) is a metabolic abnormality characterized by increased gluconeogenesis which usually contributes from an elevation of free…”
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