Search Results - "Fahmi, Nour Eddine"

Hierarchical Assembly of Nucleic Acid/Coiled-Coil Peptide Nanostructures by Buchberger, Alex, Simmons, Chad R, Fahmi, Nour Eddine, Freeman, Ronit, Stephanopoulos, Nicholas

“…DNA and peptides are two of the most commonly used biomolecules for building self-assembling materials, but few examples exist of hybrid nanostructures that…”
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Detection of Dihydrofolate Reductase Conformational Change by FRET Using Two Fluorescent Amino Acids by Chen, Shengxi, Fahmi, Nour Eddine, Wang, Lin, Bhattacharya, Chandrabali, Benkovic, Stephen J, Hecht, Sidney M

“…Two fluorescent amino acids, including the novel fluorescent species 4-biphenyl-l-phenylalanine (1), have been incorporated at positions 17 and 115 of…”
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Synthesis of pdCpAs and transfer RNAs activated with thiothreonine and derivatives by Chen, Shengxi, Fahmi, Nour Eddine, Nangreave, Ryan C., Mehellou, Youcef, Hecht, Sidney M.

“…N,S-diprotected l-thiothreonine and l-allo-thiothreonine derivatives were synthesized using a novel chemical strategy, and used for esterification of the…”
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Enhanced d-Amino Acid Incorporation into Protein by Modified Ribosomes by Dedkova, Larisa M, Fahmi, Nour Eddine, Golovine, Serguei Y, Hecht, Sidney M

“…By overexpression of modified Escherichia coli 23S rRNAs from multicopy plasmids, ribosomes were prepared that contained mutations in two regions (2447−2450…”
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Search for Cyclodextrin-Based Inhibitors of Anthrax Toxins: Synthesis, Structural Features, and Relative Activities by KARGINOV, Vladimir A, NESTOROVICH, Ekaterina M, YOHANNES, Adiamseged, ROBINSON, Tanisha M, FAHMI, Nour Eddine, SCHMIDTMANN, Frank, HECHT, Sidney M, BEZRUKOV, Sergey M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Total Synthesis of Deamido Bleomycin A2, the Major Catabolite of the Antitumor Agent Bleomycin by Zou, Ying, Fahmi, Nour Eddine, Vialas, Corine, Miller, Guy M, Hecht, Sidney M

“…Metabolic inactivation of the antitumor antibiotic bleomycin is believed to be mediated exclusively via the action of bleomycin hydrolase, a cysteine…”
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An alternative strategy for the synthesis of 3′-azido-2′,3′-dideoxy-4′-thionucleosides starting from d-xylose by Tber, Bougrine, Fahmi, Nour-Eddine, Ronco, Gino, Villa, Pierre, Ewing, David F., Mackenzie, Grahame

“…Methyl 5-O- acetyl-3-azido-2,3-dideoxy-4-thio-α,β- d-erythro- pentofuranoside and 1,5-O- diacetyl-3-azido-2,3-dideoxy-4-thio-α,β- d-erythro- pentofuranose were…”
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Rapid Photoactuation of a DNA Nanostructure using an Internal Photocaged Trigger Strand by Liu, Minghui, Jiang, Shuoxing, Loza, Omar, Fahmi, Nour Eddine, Šulc, Petr, Stephanopoulos, Nicholas

“…A reconfigurable DNA nano‐tweezer is reported that can be switched between a closed and open state with a brief pulse of UV light. In its initial state, the…”
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A Scalable Synthesis of α‑l‑Threose Nucleic Acid Monomers by Sau, Sujay P, Fahmi, Nour Eddine, Liao, Jen-Yu, Bala, Saikat, Chaput, John C

“…Recent advances in polymerase engineering have made it possible to copy information back and forth between DNA and artificial genetic polymers composed of TNA…”
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Regulating DNA Self-Assembly Dynamics with Controlled Nucleation by Jiang, Shuoxing, Pal, Nibedita, Hong, Fan, Fahmi, Nour Eddine, Hu, Huiyu, Vrbanac, Matthew, Yan, Hao, Walter, Nils G, Liu, Yan

“…Controlling the nucleation step of a self-assembly system is essential for engineering structural complexity and dynamic behaviors. Here, we design a…”
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High‐Affinity Host–Guest Recognition for Efficient Assembly and Enzymatic Responsiveness of DNA Nanostructures by Narayanan, Raghu Pradeep, Prasad, Abhay, Buchberger, Alex, Zou, Lei, Bernal‐Chanchavac, Julio, MacCulloch, Tara, Fahmi, Nour Eddine, Yan, Hao, Zhang, Fei, Webber, Matthew J., Stephanopoulos, Nicholas

“…The combination of multiple orthogonal interactions enables hierarchical complexity in self‐assembled nanoscale materials. Here, efficient supramolecular…”
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Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals by Simmons, Chad R, Buchberger, Alex, Henry, Skylar J W, Novacek, Alexandra, Fahmi, Nour Eddine, MacCulloch, Tara, Stephanopoulos, Nicholas, Yan, Hao

“…The structural analysis of guest molecules in rationally designed and self-assembling DNA crystals has proven an elusive goal since its conception…”
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β-Puromycin Selection of Modified Ribosomes for in Vitro Incorporation of β-Amino Acids by Dedkova, Larisa M, Fahmi, Nour Eddine, Paul, Rakesh, del Rosario, Melissa, Zhang, Liqiang, Chen, Shengxi, Feder, Glen, Hecht, Sidney M

“…Ribosomally mediated protein biosynthesis is limited to α-l-amino acids. A strong bias against β-l-amino acids precludes their incorporation into proteins in…”
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Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore by Henderson, J. Nathan, Simmons, Chad R, Fahmi, Nour Eddine, Jeffs, Joshua W, Borges, Chad R, Mills, Jeremy H

“…Genetically encoded fluorescent noncanonical amino acids (fNCAAs) could be used to develop novel fluorescent sensors of protein function. Previous efforts…”
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Quantum Dot-based Fluorescence Resonance Energy Transfer through Exciton Dynamics in DNA-Templated J-Aggregates by Mandal, Sarthak, Zhou, Xu, Eddine Fahmi, Nour, Lin, Su, Yan, Hao, Woodbury, Neal

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An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding by Daskalova, Sasha M., Eisenhauer, Brian M., Gao, Mingxuan, Feng, Xizhi, Ji, Xun, Cheng, Qi, Fahmi, NourEddine, Khdour, Omar M., Chen, Shengxi, Hecht, Sidney M.

“…[Display omitted] DNA polymerase β (Pol β) repairs cellular DNA damage. When such damage is inflicted upon the DNA in tumor cells treated with DNA targeted…”
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Bioactive Fibronectin-III10–DNA Origami Nanofibers Promote Cell Adhesion and Spreading by Buchberger, Alex, Riker, Kyle, Bernal-Chanchavac, Julio, Narayanan, Raghu Pradeep, Simmons, Chad R., Fahmi, Nour Eddine, Freeman, Ronit, Stephanopoulos, Nicholas

“…The integration of proteins with DNA nanotechnology would enable materials with diverse applications in biology, medicine, and engineering. Here, we describe a…”
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DNA Polymerase-Mediated Synthesis of Unbiased Threose Nucleic Acid (TNA) Polymers Requires 7‑Deazaguanine To Suppress G:G Mispairing during TNA Transcription by Dunn, Matthew R, Larsen, Andrew C, Zahurancik, Walter J, Fahmi, Nour Eddine, Meyers, Madeline, Suo, Zucai, Chaput, John C

“…Threose nucleic acid (TNA) is an unnatural genetic polymer capable of undergoing Darwinian evolution to generate folded molecules with ligand-binding activity…”
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Enantiomeric structures of a self-assembling three-dimensional DNA crystal scaffold by Simmons, Chad R., Zhang, Fei, MacCulloch, Tara, Fahmi, Nour Eddine, Stephanopoulos, Nicholas, Liu, Yan, Yan, Hao

“…Abstract only…”
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Bioactive Fibronectin-III 10 -DNA Origami Nanofibers Promote Cell Adhesion and Spreading by Buchberger, Alex, Riker, Kyle, Bernal-Chanchavac, Julio, Narayanan, Raghu Pradeep, Simmons, Chad R, Fahmi, Nour Eddine, Freeman, Ronit, Stephanopoulos, Nicholas

“…The integration of proteins with DNA nanotechnology would enable materials with diverse applications in biology, medicine, and engineering. Here, we describe a…”
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