Search Results - "Fahad Almohareb"
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An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1
Published in Blood advances (14-01-2020)“…Acute myeloid leukemia (AML) with t(8;21)(q22;q22.1);RUNX1-RUNX1T1, one of the core-binding factor leukemias, is one of the most common subtypes of AML with…”
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Risk factors and outcomes according to age at transplantation with an HLA-identical sibling for sickle cell disease
Published in Haematologica (Roma) (01-12-2019)Get full text
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Allogeneic transplant compared to pediatric-inspired therapy for Philadelphia chromosome-negative adolescent and adult ALL in first complete remission
Published in Bone marrow transplantation (Basingstoke) (01-04-2022)“…Background Pediatric-inspired non-transplant regimens for adolescent and adult ALL patients are becoming standard in many institutions. We aimed to compare a…”
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Frontline-matched sibling donor transplant of aplastic anemia patients using primed versus steady-state bone marrow grafts
Published in Annals of hematology (01-02-2022)“…Priming donors with G-CSF before BM harvest is reported to improve engraftment and GvHD in recipients. These effects are highly desirable when transplanting…”
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Outcomes of allogeneic hematopoietic cell transplant for acute myeloid leukemia in adolescent patients
Published in Bone marrow transplantation (Basingstoke) (01-01-2020)“…Patients between 14 and 22 years old are underrepresented in both adult and pediatric studies. We analyzed the outcomes of 94 consecutive patients aged between…”
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OUTCOME OF APLASTIC ANEMIA ACCORDING TO DISEASE SEVERITY
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…Objective Background: Aplastic anemia is pancytopenia with a hypocellular bone marrow [<25 % (or 25 to 50 % if <30 % of residual cells are hematopoietic)] due…”
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Posterior reversible encephalopathy syndrome post stem cell transplantation in sickle cell disease: case series and literature review
Published in Frontiers in medicine (01-05-2024)“…Posterior reversible encephalopathy syndrome (PRES) is a serious neurological syndrome that may develop following immunosuppressive therapy for stem cell…”
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Physical therapy pathway and protocol for patients undergoing hematopoietic stem cell transplantation: Recommendations from The Eastern Mediterranean Blood and Marrow Transplantation (EMBMT) Group
Published in Hematology/oncology and stem cell therapy (01-09-2019)“…Patients undergoing hematopoietic stem cell transplantation (HSCT) are often referred for physical therapy (PT) to help improve their quality of life. However,…”
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Comprehensive multi-omics analysis of G6PC3 deficiency-related congenital neutropenia with inflammatory bowel disease
Published in iScience (19-03-2021)“…Autosomal recessive mutations in G6PC3 cause isolated and syndromic congenital neutropenia which includes congenital heart disease and atypical inflammatory…”
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The outcomes of secondary AML post allogeneic hematopoietic cell transplantation significantly depend on the presence of poor‐risk cytogenetic abnormalities
Published in EJHaem (01-05-2021)“…Secondary acute myeloid leukemia (sAML) includes AML as a complication of an antecedent hematological disorder or a therapy‐related AML. Large registry‐based…”
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Establishing an autologous versus allogeneic hematopoietic cell transplant program in nations with emerging economies
Published in Hematology/oncology and stem cell therapy (01-12-2017)“…More than 70,000 hematopoietic cell transplants are currently performed each year, and these continue to increase every year. However, there is a significant…”
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Improved survival in adolescents and young adults (AYA) patients aged 14–55 years with acute lymphoblastic leukemia using pediatric-inspired protocol – a retrospective analysis of a real-world experience in 79 of patients treated at a national tertiary care referral center
Published in Leukemia research reports (01-01-2021)“…Treating adolescents and young adults (AYA) patients with acute lymphoblastic leukemia (ALL) using pediatric-inspired protocols have shown improvement in…”
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Lessons Learned from Large-Scale, First-Tier Clinical Exome Sequencing in a Highly Consanguineous Population
Published in American journal of human genetics (06-06-2019)“…We report the results of clinical exome sequencing (CES) on >2,200 previously unpublished Saudi families as a first-tier test. The predominance of…”
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Higher Relapse Rate and Resource Utilization With Ara-C Consolidation Chemotherapy Alone Compared With Hematopoietic Cell Transplantation in First Remission in a Cohort of Younger Adults With Acute Myeloid Leukemia With t(8;21) (q22;q22 .1)
Published in Clinical lymphoma, myeloma and leukemia (01-09-2024)Get full text
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AML-390 Higher Relapse Rate and Resource Utilization With Ara-C Consolidation Chemotherapy Alone Compared With Hematopoietic Cell Transplantation in First Remission in a Cohort of Younger Adults With Acute Myeloid Leukemia With t(8;21) (q22;q22.1)
Published in Clinical lymphoma, myeloma and leukemia (01-09-2024)“…Acute myeloid leukemia (AML) with t(8; 21) is classified as a favorable risk subtype, and high-dose Ara-C (HIDAC) consolidation is the recommended…”
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Excellent Outcomes of HLA Matched Related Donor Transplant for Adults with Severe Sickle Cell Disease Using a Non-Myeloablative Conditioning with Thiotepa and Post-Transplant Cyclophosphamide: Multi-Center International Experience
Published in Blood (02-11-2023)“…Introduction: The validated curative treatment for sickle cell disease (SCD) is allogeneic hematopoietic stem-cell transplantation (HSCT). Despite paucity of…”
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Lung transplantation for pulmonary graft versus host disease: experience from a referral organ transplantation center
Published in Bone marrow transplantation (Basingstoke) (01-10-2023)Get full text
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An international learning collaborative phase 2 trial for haploidentical bone marrow transplant in sickle cell disease
Published in Blood (20-06-2024)“…•For most adults with sickle cell disease, haploidentical BMT with thiotepa + PTCy is now a widely available curative option with excellent outcomes.•For…”
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