Search Results - "Fagundes, Evandro M."

Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia by Pereira‐Martins, Diego A., Coelho‐Silva, Juan L., Weinhäuser, Isabel, Franca‐Neto, Pedro L., Silveira, Douglas R., Ortiz, César, Moreira‐Aguiar, Amanda, Lima, Marinus M., Koury, Luisa C., Melo, Raul A., Glória, Ana B., Fagundes, Evandro M., Lino, Bruno K., Pagnano, Katia, Bittencourt, Rosane, Nunes, Elenaide, Traina, Fabiola, Figueiredo‐Pontes, Lorena, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dilon, Richard, Ganser, Arnold, Sanz, Miguel A., Berliner, Nancy, Valk, Peter, Löwenberg, Bob, Ottone, Tiziana, Noguera, Nelida I., Voso, Maria T., Paoloni, Francesca, Fazi, Paola, Ammatuna, Emanuele, Huls, Gerwin, Schuringa, Jan Jacob, Rego, Eduardo M., Lucena‐Araujo, Antonio R.

“…Summary Although a growing body of evidence demonstrates that altered mtDNA content (mtDNAc) has clinical implications in several types of solid tumours, its…”
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Early death and intracranial hemorrhage prediction in acute promyelocytic leukemia: validation of a risk score in a chemotherapy plus ATRA cohort from an international consortium by Silva, Wellington F, Kim, Haesook T, Undurraga, Maria S, Navarro-Cabrera, Juan R, Salinas, Victor, Muxi, Pablo, Melo, Raul A M, Gloria, Ana Beatriz F, Pagnano, Katia B B, Nunes, Elenaide C, Bittencourt, Rosane Isabel, Rojas, Ninoska, Truyenque, Shirley M Q, Ayala-Lugo, Ana Ilda, Oliver, Ana Carolina, Figueiredo-Pontes, Lorena L, Traina, Fabiola, Moreira, Frederico, Fagundes, Evandro M, Duarte, Bruno K L, Mora-Alferez, Analí Pamela, Ortiz, Percy, Untama, Jose Luis, Tallman, Martin S, Ribeiro, Raul C, Ganser, Arnold, Dillon, Richard James, Valk, Peter J M, Sanz, Miguel A, Löwenberg, Bob, Berliner, Nancy, Rego, Eduardo M

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Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines by Jacomo, Rafael Henriques, Melo, Raul Antonio Morais, Souto, Fernanda Ribeiro, de Mattos, Ederson Roberto, de Oliveira, Claudia Teresa, Fagundes, Evandro M, Bittencourt, Henrique Neves da Silva, Bittencourt, Rosane Isabel, Bortolheiro, Teresa Cristina, Paton, Eduardo J.A, Bendlin, Rodrigo, Ismael, Sebastiao, de Lourdes Chauffaille, Maria, Silva, Dirceu, Pagnano, Katia Borgia B, Ribeiro, Raul, Rego, Eduardo M

“…1 Department of Internal Medicine, Medical School of Ribeirao Preto, Brazil; 2 Molecular Biology Laboratory, HEMOPE, Brazil; 3 Bone Marrow Transplantation…”
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Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia by Lucena-Araujo, Antonio R., Pereira-Martins, Diego A., Koury, Luisa C., Franca-Neto, Pedro L., Coelho-Silva, Juan L., de Deus Wagatsuma, Virginia M., Melo, Raul A.M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Chiattone, Carlos S., Fagundes, Evandro M., Chauffaille, Maria de Lourdes, Schrier, Stanley L., Tallman, Martin S., Ribeiro, Raul C., Grimwade, David, Ganser, Arnold, Löwenberg, Bob, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M.

“…Although overexpression of the brain and acute leukemia, cytoplasmic (BAALC) gene is associated with primary resistant disease and shorter relapse-free,…”
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Clinical networking results in continuous improvement of the outcome of patients with acute promyelocytic leukemia by Koury, Luísa Corrêa de Araújo, Kim, Haesook T., Undurraga, Maria Soledad, Navarro-Cabrera, Juan Ramon, Salinas, Victor, Muxi, Pablo, Melo, Raul A. M., Glória, Ana Beatriz, Pagnano, Katia, Nunes, Elenaide C., Bittencourt, Rosane I., Rojas, Ninoska, Quintana, Shirley, Ayala-Lugo, Ana, Oliver, Ana Carolina, Figueiredo-Pontes, Lorena, Traina, Fabiola, Moreira, Frederico, Fagundes, Evandro M., Duarte, Bruno K. L., Mora-Alferez, Analí Pamela, Ortiz, Percy, Untama, Jose, Tallman, Martin, Ribeiro, Raul, Ganser, Arnold, Dillon, Richard, Valk, Peter J. M., Sanz, Miguel, Löwenberg, Bob, Berliner, Nancy, Rego, Eduardo M.

“…•The establishment of a clinical network led to significant and lasting advancements in the treatment outcomes of APL over a span of 15 years.•The overall…”
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Mortality by COVID-19 in adults with acute myeloid leukemia: a survey with hematologists in Brazil by Fagundes, Evandro M., Neto, Naira N., Caldas, Lorena M., Aragão, Jordana R., Gloria, Ana Beatriz F., Leite, Leonardo G., Bastos, Paula, Fernandes, Carolina M., Chalup, Mariana, Arcuri, Rosa, Fagundes, Olivia G.

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Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia by Lucena-Araujo, Antonio R., Coelho-Silva, Juan L., Pereira-Martins, Diego A., Silveira, Douglas R., Koury, Luisa C., Melo, Raul A.M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, de Lourdes Chauffaille, Maria, Bendit, Israel, Rocha, Vanderson, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, P.J.M., Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M.

“…By combining the analysis of mutations with aberrant expression of genes previously related to poorer prognosis in both acute promyelocytic leukemia (APL) and…”
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Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL by Rego, Eduardo M., Kim, Haesook T., Ruiz-Argüelles, Guillermo J., Undurraga, Maria Soledad, Uriarte, Maria del Rosario, Jacomo, Rafael H., Gutiérrez-Aguirre, Homero, Melo, Raul A.M., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Chauffaille, Maria de Lourdes, Chiattone, Carlos S., Martinez, Lem, Meillón, Luis A., Gómez-Almaguer, David, Kwaan, Hau C., Garcés-Eisele, Javier, Gallagher, Robert, Niemeyer, Charlotte M., Schrier, Stanley L., Tallman, Martin, Grimwade, David, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo-Coco, Francesco, Löwenberg, Bob, Sanz, Miguel A.

“…Thanks to modern treatment with all-trans retinoic acid and chemotherapy, acute promyelocytic leukemia (APL) is now the most curable type of leukemia. However,…”
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STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells by Vicari, Hugo Passos, Coelho-Silva, Juan Luiz, Pereira-Martins, Diego A., Lucena-Araujo, Antônio Roberto, Lima, Keli, Lipreri da Silva, Jean Carlos, Scheucher, Priscila Santos, Koury, Luisa C., de Melo, Raul A., Bittencourt, Rosane, Pagnano, Katia, Nunes, Elenaide, Fagundes, Evandro M., Kerbauy, Fabio, de Figueiredo-Pontes, Lorena Lobo, Costa-Lotufo, Leticia Veras, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

“…Summary Stathmin 1 (STMN1) is a microtubule-destabilizing protein highly expressed in hematological malignancies and involved in proliferation and…”
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Evaluation of the European LeukemiaNet recommendations for predicting outcomes of patients with acute myeloid leukemia treated in low- and middle-income countries (LMIC): A Brazilian experience by Benicio, Mariana Tereza de Lira, Ribeiro, Ana Flávia Tibúrcio, Américo, Andre D., Furtado, Felipe M., Glória, Ana B., Lima, Aleide S., Santos, Silvana M., Xavier, Sandra G., Lucena-Araujo, Antonio R., Fagundes, Evandro M., Rego, Eduardo M.

“…•ELN recommendations may be used for risk stratification of AML patients in LMIC.•OS, DFS and EFS in LMIC were shorter than the reported in Europe and…”
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Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study by Lucena-Araujo, Antonio R., Kim, Haesook T., Jacomo, Rafael H., Melo, Raul A., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Chauffaille, Maria de Lourdes, Chiattone, Carlos S., Lima, Ana Silvia, Ruiz-Argüelles, Guillermo, Undurraga, Maria Soledad, Martinez, Lem, Kwaan, Hau C., Gallagher, Robert, Niemeyer, Charlotte M., Schrier, Stanley L., Tallman, Martin S., Grimwade, David, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo-Coco, Francesco, Löwenberg, Bob, Sanz, Miguel A., Rego, Eduardo M.

“…Activating internal tandem duplication (ITD) mutations in the fms - like tyrosine kinase 3 ( FLT3 ) gene ( FLT3 -ITD) are associated with poor outcome in acute…”
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The experience of the International Consortium on Acute Promyelocytic Leukemia in monitoring minimal residual disease in acute promyelocytic leukaemia by Lange, Ana P., Lima, Ana S., Lucena‐Araujo, Antonio R., Jácomo, Rafael H., Melo, Raul A., Bittencourt, Rosane I., Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Chauffaille, Maria L., Chiattone, Carlos S., Sanz, Miguel A., Lo‐Coco, Francesco, Grimwade, David, Rego, Eduardo M.

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Association of Human Development Index with rates and outcomes of hematopoietic stem cell transplantation for patients with acute leukemia by Giebel, Sebastian, Labopin, Myriam, Ehninger, Gerhard, Beelen, Dietrich, Blaise, Didier, Ganser, Arnold, Bacigalupo, Andrea, Czerw, Tomasz, Holowiecki, Jerzy, Fagundes, Evandro M., Nowara, Elzbieta, Frassoni, Francesco, Rocha, Vanderson

“…Human Development Index (HDI) is used by the United Nations Organization to measure socioeconomic achievements of countries. We evaluated the association of…”
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Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia by Weinhäuser, Isabel, Pereira-Martins, Diego A., Ortiz, Cesar, Silveira, Douglas R., Simões, Luíse A. A., Bianco, Thiago M., Araujo, Cleide L., Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane I., Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Ammatuna, Emanuele, Lucena-Araujo, Antonio R., Schuringa, Jan Jacob, Rego, Eduardo M.

“…The SLIT-ROBO axis plays an important role in normal stem-cell biology, with possible repercussions on cancer stem cell emergence. Although the Promyelocytic…”
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Characterization of NPM1, FLT3, and IDH1 mutations in adult patients with acute myeloid leukemia: a Brazilian cohort study by Cruz, Nathália Gomide, Ribeiro, Ana Flávia Tibúrcio, Glória, Ana Beatriz Firmato, Abbas, Saman, Assumpção, Juliana Godoy, Santos, Silvana Maria Eloi, Rezende, Suely Meireles, Xavier, Sandra Guerra, Fagundes, Evandro M.

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All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies by Sanz, Miguel A., Montesinos, Pau, Kim, Haesook T., Ruiz-Argüelles, Guillermo J., Undurraga, María S., Uriarte, María R., Martínez, Lem, Jacomo, Rafael H., Gutiérrez-Aguirre, Homero, Melo, Raul A. M., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Vellenga, Edo, Holowiecka, Alexandra, González-Huerta, Ana J., Fernández, Pascual, De la Serna, Javier, Brunet, Salut, De Lisa, Elena, González-Campos, José, Ribera, José M., Krsnik, Isabel, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo-Coco, Francesco, Löwenberg, Bob, Rego, Eduardo M.

“…Front-line treatment of acute promyelocytic leukaemia (APL) consists of all- trans retinoic acid (ATRA) and anthracycline-based chemotherapy. In this setting,…”
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Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all‐trans retinoic acid and anthracycline‐based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study by Lucena‐Araujo, Antonio R., Kim, Haesook T., Jacomo, Rafael H., Melo, Raul A., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Chauffaille, Maria, Chiattone, Carlos S., Lima, Ana S., Kwaan, Hau C., Gallagher, Robert, Niemeyer, Charlotte M., Schrier, Stanley L., Tallman, Martin S., Grimwade, David, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo‐Coco, Francesco, Löwenberg, Bob, Sanz, Miguel A., Rego, Eduardo M.

“…Summary The KMT2E (MLL5) gene encodes a histone methyltransferase implicated in the positive control of genes related to haematopoiesis. Its close relationship…”
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De novo acute myeloid leukemia in adults younger than 60 years of age: Socioeconomic aspects and treatment results in a Brazilian university center by Fagundes, Evandro M., Rocha, Vanderson, Glória, Ana Beatriz F., Clementino, Nelma Cristina D., Quintão, José S., Guimarães, João Paulo O., Pedroso, Ênio Roberto P., Viana, Marcos B.

“…We retrospectively studied the outcomes of adults with de novo acute myeloid leukemia treated in a reference center in Brazil and analyzed the association with…”
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The impact of medical education and networking on the outcome of leukemia treatment in developing countries. The experience of International Consortium on Acute Promyelocytic Leukemia (IC-APL) by Rego, Eduardo M, Kim, Haesook T, Ruiz-Argüelles, Guillermo J, Uriarte, Maria del Rosario, Jacomo, Rafael H, Gutiérrez-Aguirre, Homero, Melo, Raul A M, Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M, Chauffaille, Maria de Lourdes, Chiattone, Carlos, Martinez, Lem, Meillón, Luis A, Gómez-Almaguer, David, Kwaan, Hau, Garcés-Eisele, Javier, Gallagher, Robert, Niemeyer, Charlotte M, Lowenberg, Bob, Ribeiro, Raul, LoCoco, Francesco, Sanz, Miguel A

“…Several clinical trials conducted in Europe and US reported favorable outcomes of patients with APL treated with the combination of all trans retinoic acid…”
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Granulocytic sarcoma of the small intestine with CBFβ/ MYH11 fusion gene: report of an aleukaemic case and review of the literature by Xavier, Sandra G, Fagundes, Evandro M, Hassan, Rocı́o, Bacchi, Carlos, Conchon, Mônika, Tabak, Daniel G, Spector, Nelson, Zalcberg, Ilana R

“…Granulocytic sarcomas (GS) are rare extramedullary tumours composed of immature myeloid cells. Inversion of chromosome 16 [inv(16)] is a cytogenetic marker for…”
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