Search Results - "Fagin, J.A."
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3 INVITED RET inhibition: therapeutic implications in thyroid cancer
Published in European journal of cancer supplements (2008)Get full text
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Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and post-transcriptional mechanisms
Published in The Journal of biological chemistry (25-01-1993)“…Parathyroid hormone-related protein (PTHrP), a tumor product responsible for malignancy-associated hypercalcemia, is also produced in many normal tissues,…”
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Transformation by [Hras.sup.G12V] is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition
Published in Oncogene (20-11-2014)“…RAS-driven malignancies remain a major therapeutic challenge. The two-stage 7,12-dimethylbenz(a)anthracene (DMBA)/12-o- tetradecanoylphorbol-13-acetate (TPA)…”
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Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling
Published in Oncogene (14-07-2011)“…Mice with thyroid-specific expression of oncogenic BRAF ( Tg-Braf ) develop papillary thyroid cancers (PTCs) that are locally invasive and have well-defined…”
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Cloning and characterization of alternatively spliced isoforms of rat tenascin. Platelet-derived growth factor-BB markedly stimulates expression of spliced variants of tenascin mRNA in arterial smooth muscle cells
Published in The Journal of biological chemistry (12-08-1994)“…To understand the alteration of extracellular matrix composition evoked by chemotactic factors, we have studied the expression of adhesive (fibronectin) and…”
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Thyroid lesions in children and adolescents after the Chernobyl disaster: implications for the study of radiation tumorigenesis
Published in The journal of clinical endocrinology and metabolism (01-01-1996)“…Eight years after the Chernobyl nuclear accident, the most obvious effect is manifested by an increase in the prevalence of thyroid gland diseases in the…”
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From Amplification to Gene in Thyroid Cancer: A High-Resolution Mapped Bacterial-Artificial-Chromosome Resource for Cancer Chromosome Aberrations Guides Gene Discovery after Comparative Genome Hybridization
Published in American journal of human genetics (01-08-1998)“…Chromosome rearrangements associated with neoplasms provide a rich resource for definition of the pathways of tumorigenesis. The power of comparative genome…”
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Angiotensin II regulates tenascin gene expression in vascular smooth muscle cells
Published in The Journal of biological chemistry (25-11-1992)“…Angiotensin II, a vasoactive peptide, has been implicated in the pathophysiology of a number of vascular wall abnormalities. Since aberrant extracellular…”
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Preface
Published in Baillière's clinical endocrinology and metabolism (01-04-1995)Get full text
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Gene amplification in thyroid cancer: A new mechanism defined by CGH and A BAC map of the human genome
Published in Cancer genetics and cytogenetics (01-10-1995)Get full text
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