Search Results - "Fagbami, Lola"
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…A coding polymorphism (Thr300Ala) in the essential autophagy gene, autophagy related 16-like 1 (ATG16L1), confers increased risk for the development of Crohn…”
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Reduced-representation Phosphosignatures Measured by Quantitative Targeted MS Capture Cellular States and Enable Large-scale Comparison of Drug-induced Phenotypes
Published in Molecular & cellular proteomics (01-05-2016)“…Profiling post-translational modifications represents an alternative dimension to gene expression data in characterizing cellular processes. Many cellular…”
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Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy
Published in Cell reports (Cambridge) (30-06-2015)“…The polymorphism ATG16L1 T300A, associated with increased risk of Crohn’s disease, impairs pathogen defense mechanisms including selective autophagy, but…”
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Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance
Published in Nature communications (25-08-2022)“…© The Author(s) 2022 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays
Published in Analytical chemistry (Washington) (02-08-2016)“…Immunoaffinity enrichment of peptides coupled with analysis by stable isotope dilution multiple reaction mass spectrometry has been shown to have analytical…”
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Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Published in Cell systems (28-09-2016)“…Genome-scale expression studies and comprehensive loss-of-function genetic screens have focused almost exclusively on the highest confidence candidate genes…”
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The Adaptive Proline Response in P. falciparum Is Independent of Pf eIK1 and eIF2α Signaling
Published in ACS infectious diseases (12-04-2019)Get full text
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The Adaptive Proline Response in P. falciparum Is Independent of PfeIK1 and eIF2α Signaling
Published in ACS infectious diseases (12-04-2019)“…We have previously identified the cytoplasmic prolyl tRNA synthetase in Plasmodium falciparum as the functional target of the natural product febrifugine and…”
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