Search Results - "Fagan, Patrick"

Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor by Yokoyama, Yumi, Lew, Erin D, Seelige, Ruth, Tindall, Elizabeth A, Walsh, Colin, Fagan, Patrick C, Lee, Jack Y, Nevarez, Robin, Oh, Joanne, Tucker, Kathleen D, Chen, Marissa, Diliberto, Amy, Vaaler, Heather, Smith, Kristen M, Albert, Amanda, Li, Gary, Bui, Jack D

“…Expression of the TAM (TYRO3, AXL, MER) family of receptor tyrosine kinases (RTK) has been associated with cancer progression, metastasis, and drug resistance…”
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Antitumor Activity of Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor, in ETV6-NTRK3 -Positive Acute Myeloid Leukemia by Smith, Kristen M, Fagan, Patrick C, Pomari, Elena, Germano, Giuseppe, Frasson, Chiara, Walsh, Colin, Silverman, Ian, Bonvini, Paolo, Li, Gang

“…Activation of tropomyosin receptor kinase (TRK) family tyrosine kinases by chromosomal rearrangement has been shown to drive a wide range of solid tumors and…”
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RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells by Hawk, Mark A., Gorsuch, Cassandra L., Fagan, Patrick, Lee, Chan, Kim, Sung Eun, Hamann, Jens C., Mason, Joshua A., Weigel, Kelsey J., Tsegaye, Matyas Abel, Shen, Luqun, Shuff, Sydney, Zuo, Junjun, Hu, Stephan, Jiang, Lei, Chapman, Sarah, Leevy, W. Matthew, DeBerardinis, Ralph J., Overholtzer, Michael, Schafer, Zachary T.

“…For cancer cells to survive during extracellular matrix (ECM) detachment, they must inhibit anoikis and rectify metabolic deficiencies that cause non-apoptotic…”
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High-Frequency Fractional Predictions and Spatial Distribution of the Magnetic Loss in a Grain-Oriented Magnetic Steel Lamination by Ducharne, Benjamin, Hamzehbahmani, Hamed, Gao, Yanhui, Fagan, Patrick, Sebald, Gael

“…Grain-oriented silicon steel (GO FeSi) laminations are vital components for efficient energy conversion in electromagnetic devices. While traditionally…”
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Clicks and tricks: The dark art of online persuasion by Fagan, Patrick

“…Internet users are inundated with attempts to persuade, including digital nudges like defaults, friction, and reinforcement. When these nudges fail to be…”
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Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung by Stebbins, Karin J, Broadhead, Alex R, Baccei, Christopher S, Scott, Jill M, Truong, Yen P, Coate, Heather, Stock, Nicholas S, Santini, Angelina M, Fagan, Patrick, Prodanovich, Patricia, Bain, Gretchen, Stearns, Brian A, King, Christopher D, Hutchinson, John H, Prasit, Peppi, Evans, Jilly F, Lorrain, Daniel S

“…Prostaglandin D(2) (PGD(2)) is one of a family of biologically active lipids derived from arachidonic acid via the action of COX-1 and COX-2. PGD(2) is…”
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Morphological Changes on Neuromuscular Ultrasound in Nerves Distal to Gunshot Injuries (P14-8.003) by Fagan, Patrick, Geiger, Christopher, Preston, David

“…Abstract only…”
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Effect of Tension and Compression Stress on the Magnetic Losses in a Low-Carbon Steel by Ouazib, Abderraouf, Domenjoud, Mathieu, Fagan, Patrick, Daniel, Laurent

“…This work is an experimental study of the evolution of magnetic losses in dc-04 steel under static mechanical stress. The material was subjected, in the…”
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Magnetic hysteresis cycle measurements with a new needle probe setup by Fagan, Patrick, Abderahmane, Abdellahi, Domenjoud, Mathieu, Daniel, Laurent

“…Different magnetic needle probe setups are presented, and their strengths and weaknesses are investigated. A new configuration, combining the advantages of the…”
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Effect of stress on the magnetic Barkhausen noise energy cycles: A route for stress evaluation in ferromagnetic materials by Fagan, Patrick, Ducharne, Benjamin, Daniel, Laurent, Skarlatos, Anastasios, Domenjoud, Mathieu, Reboud, Christophe

“…•Tensile stress is evaluated from magnetic Barkhausen noise energy hysteresis loops.•Coercivity is the most sensitive tensile stress indicator.•A simulation…”
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Pricing practices: A critical review of their effects on consumer perceptions and behaviour by Ahmetoglu, Gorkan, Furnham, Adrian, Fagan, Patrick

“…With the present challenge to compete on price or product assortment, retailers and manufacturers are increasingly focusing on state-of-the-art pricing…”
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Neuromuscular ultrasound findings in gunshot wounds by Fagan, Patrick, Geiger, Christopher D., Chenji, Gaurav, Preston, David C.

“…Introduction/Aims A spectrum of peripheral nerve injuries is associated with gunshot wounds (GSWs). Due to Wallerian degeneration, distal nerve lesions may go…”
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Barkhausen noise hysteresis cycle: Theoretical and experimental understanding by Fagan, Patrick, Zhang, Shurui, Sebald, Gael, Uchimoto, Tetsuya, Ducharne, Benjamin

“…•MBNenergy is a time-average variable induced from the raw Barkhausen noise signal.•The definition of MBNenergy and its link with the flux density is…”
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Paroxysmal Hypertension in Congenital Hypothyroidism: An Unusual Case of Pheochromocytoma by Fagan, Patrick, McLaughlin, Conor J, Fugok, Kimberly L, Desai, Tasha

“…Pheochromocytomas are rare tumors arising from the chromaffin cells of the adrenal medulla that result in the secretion of excessive catecholamines. They are…”
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Iterative methods for waveform control in magnetic measurement systems by Fagan, Patrick, Ducharne, Benjamin, Zurek, Stanislaw, Domenjoud, Mathieu, Skarlatos, Anastasios, Daniel, Laurent, Reboud, Christophe

“…Magnetic losses in a ferromagnetic lamination can be separated into three contributions. Bertotti theoretically assessed this distribution at the end of the…”
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Multiscale modelling of the magnetic Barkhausen noise energy cycles by Fagan, P., Ducharne, B., Daniel, L., Skarlatos, A.

“…[Display omitted] •MBNenergy hysteresis cycles are simulated using a multi-scale model.•A multi-scale model is combined to the Jiles-Atherton model.•Rotation…”
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Familia y Educación by Fagan, Patrick F.

“…El objetivo de este trabajo es examinar la relación íntima entre la familia y la educación y revelar las implicaciones sociales y educativas subyacentes del…”
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Testing the effect of consumer-model racial congruency on consumer behavior by Forbes-Bell, Shakaila, Bardey, Aurore C, Fagan, Patrick

“…Black, Asian, and Minority Ethnic (BAME) models continue to be underrepresented in advertising within the fashion and beauty industry. The present research…”
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Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors by Cheng, Hengmiao, Li, Puhui, Chen, Ping, Irimia, Adriana, Bae, Jae Hyun, Brooun, Alexei, Fagan, Patrick, Lam, Richard, Lin, Bingzhen, Zhang, Jingchuan, Zhan, Xuejun, Wu, Xu, Xie, Nan, Chiang, Gary, Shoemaker, Robert, Vernier, Jean-Michel

“…KRAS G12D mutation has been found in approximately 45% of pancreatic ductal adeno­carcinoma (PDAC) cases, making it an attractive therapeutic target. Through…”
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Abstract 3550: Activation of a novel form of regulated necrosis to eliminate extracellular matrix detached epithelial cells by Hawk, Mark A., Buchheit, Cassandra L., Shen, Luqun, Fagan, Patrick, Schafer, Zachary T.

“…The overwhelming majority of breast cancer deaths are caused by the metastasis of cancer cells from the primary tumor to distant sites in the body. For cancer…”
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