Search Results - "Faehling, Michael"

Understanding and preventing contrast-induced acute kidney injury by Fähling, Michael, Seeliger, Erdmann, Patzak, Andreas, Persson, Pontus B.

“…Key Points The incidence of contrast-induced acute kidney injury (CIAKI) is disputed, but clinically relevant CIAKI is less frequent than previously assumed…”
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A triple sense of oxygen promotes neurovascular angiogenesis in NG2‐derived cells by Rosenberger, Christian, Fähling, Michael

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D‐serine—A useful biomarker for renal injury? by Spasova, Kameliya, Fähling, Michael

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How to increase cellular oxygen availability in COVID‐19? by Kulow, Vera A., Fähling, Michael

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Surviving hypoxia by modulation of mRNA translation rate by Fähling, Michael

“…•  Oxygen in eukaryotic metabolism •  Oxygen consumption of tissues and processes •  Metabolic rate depression •  mRNA translation in hypoxia: the down and up…”
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Galectin-3 protects distal convoluted tubules in rhabdomyolysis-induced kidney injury by Kulow, Vera A., Labes, Robert, Czopek, Claudia S., Rosenberger, Christian, Fähling, Michael

“…Advanced glycation endproducts (AGEs) contribute to cellular damage of various pathologies, including kidney diseases. Acute kidney injury (AKI) represents a…”
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Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease by Derkow, Katja, Rössling, Rosa, Schipke, Carola, Krüger, Christina, Bauer, Jakob, Fähling, Michael, Stroux, Andrea, Schott, Eckart, Ruprecht, Klemens, Peters, Oliver, Lehnardt, Seija

“…MicroRNAs (miRNAs) are non-coding RNAs originally involved in RNA silencing and post-transcriptional regulation of gene expression. We have shown in previous…”
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Alignment-Annotator web server: rendering and annotating sequence alignments by Gille, Christoph, Fähling, Michael, Weyand, Birgit, Wieland, Thomas, Gille, Andreas

“…Alignment-Annotator is a novel web service designed to generate interactive views of annotated nucleotide and amino acid sequence alignments (i) de novo and…”
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A broad diversity in oxygen affinity to haemoglobin by Balcerek, Björn, Steinach, Mathias, Lichti, Julia, Maggioni, Martina A., Becker, Philipp N., Labes, Robert, Gunga, Hanns-Christian, Persson, Pontus B., Fähling, Michael

“…Oxygen affinity to haemoglobin is indicated by the p50 value (pO 2 at 50% O 2 Hb) and critically determines cellular oxygen availability. Although high Hb-O 2…”
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A fluid shift for endurance exercise—Why hydration matters by Steinach, Mathias, Lichti, Julia, Maggioni, Martina Anna, Fähling, Michael

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Chimeric HDAC and the cytoskeleton inhibitor broxbam as a novel therapeutic strategy for liver cancer by Bär, Sofia Isolde, Dittmer, Alexandra, Nitzsche, Bianca, Ter-Avetisyan, Gohar, Fähling, Michael, Klefenz, Adrian, Kaps, Leonard, Biersack, Bernhard, Schobert, Rainer, Höpfner, Michael

“…Broxbam, also known as N-hydroxy-4-{1-methoxy-4-[4'-(3'-bromo-4',5'-dimethoxyphenyl)-oxazol-5'-yl]-2-phenoxy} butanamide, is a novel chimeric inhibitor that…”
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Tubular von Hippel-Lindau Knockout Protects against Rhabdomyolysis-Induced AKI by FÄHLING, Michael, MATHIA, Susanne, PALIEGE, Alexander, KOESTERS, Robert, MROWKA, Ralf, PETERS, Harm, PERSSON, Pontus Börje, NEUMAYER, Hans-Hellmut, BACHMANN, Sebastian, ROSENBERGER, Christian

“…Renal hypoxia occurs in AKI of various etiologies, but adaptation to hypoxia, mediated by hypoxia-inducible factor (HIF), is incomplete in these conditions…”
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NFAT5 regulates renal gene expression in response to angiotensin II through Annexin-A2-mediated posttranscriptional regulation in hypertensive rats by Fähling, Michael, Paliege, Alexander, Jönsson, Sofia, Becirovic-Agic, Mediha, Melville, Jacqueline M, Skogstrand, Trude, Hultström, Michael

“…The aim was to identify new targets that regulate gene expression at the posttranscriptional level in angiotensin II (ANGII)-mediated hypertension. Heparin…”
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Beyond hemoglobin: Critical role of 2,3-bisphosphoglycerate mutase in kidney function and injury by Kulow, Vera A, Roegner, Kameliya, Labes, Robert, Kasim, Mumtaz, Mathia, Susanne, Czopek, Claudia S, Berndt, Nikolaus, Becker, Philipp N, Ter-Avetisyan, Gohar, Luft, Friedrich C, Enghard, Philipp, Hinze, Christian, Klocke, Jan, Eckardt, Kai-Uwe, Schmidt-Ott, Kai M, Persson, Pontus B, Rosenberger, Christian, Fähling, Michael

“…2,3-bisphosphoglycerate mutase (BPGM) is traditionally recognized for its role in modulating oxygen affinity to hemoglobin in erythrocytes. Recent…”
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Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells by Giesecke, Torsten, Himmerkus, Nina, Leipziger, Jens, Bleich, Markus, Koshimizu, Taka-Aki, Fähling, Michael, Smorodchenko, Alina, Shpak, Julia, Knappe, Carolin, Isermann, Julian, Ayasse, Niklas, Kawahara, Katsumasa, Schmoranzer, Jan, Gimber, Niclas, Paliege, Alexander, Bachmann, Sebastian, Mutig, Kerim

“…Antagonists of the V1a vasopressin receptor (V1aR) are emerging as a strategy for slowing progression of CKD. Physiologically, V1aR signaling has been linked…”
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Nucleic acid binding of annexin A2 is regulated through angiotensin II/AT1 signaling in kidneys of hypertensive rats (1088.2) by Hultström, Michael, Paliege, Alexander, Skogstrand, Trude, Fähling, Michael

“…The aim was to identify new targets that regulate gene expression at the post‐transcriptional level in hypertension. Heparin affinity chromatography was…”
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The relevance of body composition assessment for the rating of perceived exertion in trained and untrained women and men by Lichti, Julia, Maggioni, Martina Anna, Balcerek, Björn, Becker, Philipp Nils, Labes, Robert, Gunga, Hanns-Christian, Fähling, Michael, Steinach, Mathias

“…Introduction: Mechanic power output (MPO) and oxygen consumption (VO 2 ) reflect endurance capacity and are often stated relative to body mass (BM) but less…”
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Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer by Steinemann, Gustav, Dittmer, Alexandra, Schmidt, Jacob, Josuttis, David, Fähling, Michael, Biersack, Bernhard, Beindorff, Nicola, Jolante Koziolek, Eva, Schobert, Rainer, Brenner, Winfried, Müller, Thomas, Nitzsche, Bianca, Höpfner, Michael

“…Chimeric inhibitors, which merge two drug pharmacophores in a single molecule have become a prominent approach for the design of novel anticancer compounds…”
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Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum by Staudacher, Jonas J, Naarmann-de Vries, Isabel S, Ujvari, Stefanie J, Klinger, Bertram, Kasim, Mumtaz, Benko, Edgar, Ostareck-Lederer, Antje, Ostareck, Dirk H, Bondke Persson, Anja, Lorenzen, Stephan, Meier, Jochen C, Blüthgen, Nils, Persson, Pontus B, Henrion-Caude, Alexandra, Mrowka, Ralf, Fähling, Michael

“…Protein synthesis is a primary energy-consuming process in the cell. Therefore, under hypoxic conditions, rapid inhibition of global mRNA translation…”
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Splice-specific roles of glycine receptor alpha 3 in the hippocampus by Eichler, Sabrina A, Foerstera, Benjamin, Smolinsky, Birthe, Juettner, Rene, Lehmann, Thomas-Nicolas, Faehling, Michael, Schwarz, Guenter, Legendre, Pascal, Meier, Jochen C

“…AbstractGlycine receptor (GlyR) alpha 3 is involved in vision, and processing of acoustic and nociceptive signals, and RNA editing of GLRA3 transcripts was…”
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