Search Results - "Fadzeyeva, Evgenia"
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Dipeptidyl Peptidase-4 at the Interface Between Inflammation and Metabolism
Published in Clinical Medicine Insights: Endocrinology and Diabetes (2020)“…Dipeptidyl peptidase-4 (DPP4) is a serine protease that rapidly inactivates the incretin peptides, glucagon-like peptide-1, and glucose-dependent…”
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Book Review Journal Article -
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Nobiletin Prevents High-Fat Diet-Induced Dysregulation of Intestinal Lipid Metabolism and Attenuates Postprandial Lipemia
Published in Arteriosclerosis, thrombosis, and vascular biology (01-02-2022)“…Nobiletin is a dietary flavonoid that improves insulin resistance and atherosclerosis in mice with metabolic dysfunction. Dysregulation of intestinal…”
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14-3-3ζ Constrains insulin secretion by regulating mitochondrial function in pancreatic β cells
Published in JCI insight (22-04-2022)“…While critical for neurotransmitter synthesis, 14-3-3 proteins are often assumed to have redundant functions due to their ubiquitous expression, but despite…”
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Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
Published in iScience (19-05-2023)“…Mice systemically lacking dipeptidyl peptidase-4 (DPP4) have improved islet health, glucoregulation, and reduced obesity with high-fat diet (HFD) feeding…”
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Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression
Published in JCI insight (24-01-2023)“…Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty…”
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321-OR: Deletion of 14-3-3ζ in Pancreatic ß-Cells Increase Mitochondrial Activity and Insulin Secretion
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Pancreatic β-cells continuously sense blood glucose levels and secrete insulin to maintain normoglycemia. In β-cells, ATP generated by glycolysis promotes the…”
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Cisplatin Impairs Mitochondrial Function and Insulin Secretion in Mouse Islets
Published in Canadian journal of diabetes (01-11-2022)Get full text
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Metabolic and Cardiovascular Impact of Ketotic Extreme Carbohydrate Restriction
Published in Canadian journal of diabetes (01-11-2021)Get full text
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9 - Regulation of Glucose Metabolism via the Intra-Islet DPP4/Incretin Axis
Published in Canadian journal of diabetes (01-10-2020)Get full text
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66 - Elimination of Hepatocyte Dpp4 Does Not Alter Markers of Liver Disease Progression in Aged, High-Fat, High-Cholesterol-Fed Mice
Published in Canadian journal of diabetes (01-10-2020)Get full text
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Investigating the Relationship Between Pollutant Concentrations in Human Pancreas and Adipose Tissues and Beta-cell Dysfunction
Published in Canadian journal of diabetes (01-11-2022)Get full text
Journal Article