Search Results - "Fademrecht, Silvia"
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Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes
Published in Angewandte Chemie International Edition (02-01-2019)“…The direct enantioselective addition of water to unactivated alkenes could simplify the synthesis of chiral alcohols and solve a long‐standing challenge in…”
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2
Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases
Published in Chembiochem : a European journal of chemical biology (13-10-2014)“…Reducing reactions are among the most useful transformations for the generation of chiral compounds in the fine‐chemical industry. Because of their exquisite…”
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3
Percolation in protein sequence space
Published in PloS one (20-12-2017)“…The currently known protein sequences are not distributed equally in sequence space, but cluster into families. Analyzing the cluster size distribution gives a…”
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4
Biocatalytic study of novel oleate hydratases
Published in Journal of molecular catalysis. B, Enzymatic (01-11-2016)“…[Display omitted] •Establishment of Hydratase Engineering Database comprising 2046 oleate hydratases.•Cloning and heterologous expression of nine selected…”
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5
Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes
Published in Angewandte Chemie (02-01-2019)“…The direct enantioselective addition of water to unactivated alkenes could simplify the synthesis of chiral alcohols and solve a long‐standing challenge in…”
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Journal Article -
6
New imine-reducing enzymes from β-hydroxyacid dehydrogenases by single amino acid substitutions
Published in Protein engineering, design and selection (01-04-2018)“…Abstract We report the exploration of the evolutionary relationship between imine reductases (IREDs) and other dehydrogenases. This approach is informed by the…”
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7
Network Analysis of Sequence-Function Relationships and Exploration of Sequence Space of TEM β-Lactamases
Published in Antimicrobial agents and chemotherapy (01-05-2016)“…The Lactamase Engineering Database (www.LacED.uni-stuttgart.de) was developed to facilitate the classification and analysis of TEM β-lactamases. The current…”
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8
Identification of imine reductase-specific sequence motifs
Published in Proteins, structure, function, and bioinformatics (01-05-2016)“…ABSTRACT Chiral amines are valuable building blocks for the production of a variety of pharmaceuticals, agrochemicals and other specialty chemicals. Only…”
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Molecular Surface Maps
Published in IEEE transactions on visualization and computer graphics (01-01-2017)“…We present Molecular Surface Maps, a novel, view-independent, and concise representation for molecular surfaces. It transfers the well-known world map metaphor…”
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Cover Image, Volume 84, Issue 5
Published in Proteins, structure, function, and bioinformatics (01-05-2016)“…The cover image, by Jurgen Pleiss et al., is based on the Article Identification of imine reductase-specific sequence motifs, 10.1002/prot.25008…”
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