Search Results - "Fadel, J.R"
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Repeated restraint stress-induced atrophy of glutamatergic pyramidal neurons and decreases in glutamatergic efflux in the rat amygdala are prevented by the antidepressant agomelatine
Published in Neuroscience (22-01-2015)“…Highlights • Repeated restraint stress (RRS) elicits atrophy of pyramidal neurons in the rat basolateral nucleus of the amygdala (CBL). • RRS decreases acute…”
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Aging-related alterations in orexin/hypocretin modulation of septo-hippocampal amino acid neurotransmission
Published in Neuroscience (10-11-2011)“…Abstract GABAergic neurons of the medial septum of the basal forebrain make up a substantial portion of the septo-hippocampal pathway fibers, and are known to…”
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Interactions between pyridostigmine bromide and stress on glutamatergic neurochemistry: Insights from a rat model of Gulf War Illness
Published in Neurobiology of stress (01-05-2020)“…Pyridostigmine bromide (PB) was administered to soldiers during the first Gulf War as a prophylactic treatment to protect against toxicity in the event of…”
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Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats
Published in Neurobiology of stress (01-05-2022)“…Gulf War Illness (GWI) is a multi-symptom illness that continues to affect over 250,000 American Gulf War veterans. The causes of GWI remain equivocal;…”
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Activation of phenotypically-distinct neuronal subpopulations of the rat amygdala following exposure to predator odor
Published in Neuroscience (17-02-2011)“…Abstract Exposure of rats to an odor of a predator can elicit an innate fear response. In addition, such exposure has been shown to activate limbic brain…”
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Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness
Published in Brain, behavior, and immunity (01-08-2019)“…•Whether PB can impact central cholinergic neurotransmission is controversial.•Responses to an immune challenge are potentiated in PB-treated rats.•The impact…”
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Delayed cognitive impairments in a rat model of Gulf War Illness are stimulus-dependent
Published in Brain, behavior, and immunity (01-10-2023)“…•PB treatment elicits long-term disruptions in the central cholinergic system.•Cholinergic disruptions emerge when stimulated by physiological…”
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