Search Results - "Fadeel, Bengt"
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Hide and Seek: Nanomaterial Interactions With the Immune System
Published in Frontiers in immunology (2019)“…Engineered nanomaterials hold promise for a wide range of applications in medicine. However, safe use of nanomaterials requires that interactions with…”
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Intra- and Extracellular Degradation of Neutrophil Extracellular Traps by Macrophages and Dendritic Cells
Published in The Journal of immunology (1950) (15-10-2019)“…Neutrophil extracellular traps (NETs) composed of nuclear DNA associated with histones and granule proteins are involved in the extracellular killing of…”
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Macrophage clearance of neutrophil extracellular traps is a silent process
Published in The Journal of immunology (1950) (01-09-2013)“…Neutrophil extracellular traps (NETs) facilitate the extracellular killing of pathogens. However, in recent years, excessive NET formation has been implicated…”
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Grouping all carbon nanotubes into a single substance category is scientifically unjustified
Published in Nature nanotechnology (01-03-2020)Get full text
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Three cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death
Published in Cell death discovery (08-02-2019)“…Macrophage clearance of apoptotic cells has been extensively investigated, but less is known regarding the clearance of cells dying by other forms of…”
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Biological interactions of carbon-based nanomaterials: From coronation to degradation
Published in Nanomedicine (01-02-2016)“…Abstract Carbon-based nanomaterials including carbon nanotubes, graphene oxide, fullerenes and nanodiamonds are potential candidates for various applications…”
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Comment on “The long life of unicorns”
Published in Precision nanomedicine (09-12-2020)“…In a recent paper, Erden and Lévy discuss how misconceptions may persist in the scientific literature; the authors refer to these misconstrued ideas as…”
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Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications
Published in Advanced drug delivery reviews (08-03-2010)“…The development of nanoparticles for biomedical applications including medical imaging and drug delivery is currently undergoing a dramatic expansion. However,…”
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Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials
Published in Accounts of chemical research (19-03-2013)“…Engineered nanomaterials offer numerous and tantalizing opportunities in many sectors of society, including medicine. Needless to say, attention should also be…”
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The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease
Published in Critical reviews in biochemistry and molecular biology (01-10-2009)“…A common feature of all eukaryotic membranes is the non-random distribution of different lipid species in the lipid bilayer (lipid asymmetry). Lipid asymmetry…”
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Clear and present danger? Engineered nanoparticles and the immune system
Published in Swiss medical weekly (2012)“…The innate immune system is the first line of defense against microbial invasion and involves the recognition of pathogen-associated molecular patterns (PAMPs)…”
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Degradation of Single‐Layer and Few‐Layer Graphene by Neutrophil Myeloperoxidase
Published in Angewandte Chemie International Edition (03-09-2018)“…Biodegradability of graphene is one of the fundamental parameters determining the fate of this material in vivo. Two types of aqueous dispersible graphene,…”
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Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release
Published in Particle and fibre toxicology (17-02-2014)“…Silver nanoparticles (AgNPs) are currently one of the most manufactured nanomaterials. A wide range of toxicity studies have been performed on various AgNPs,…”
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Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation
Published in Biochimica et biophysica acta (01-03-2011)“…BACKGROUND: It is widely believed that engineered nanomaterials will be increasingly used in biomedical applications. However, before these novel materials can…”
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Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)
Published in Particle and fibre toxicology (10-05-2022)“…Copper oxide (CuO) nanoparticles (NPs) are known to trigger cytotoxicity in a variety of cell models, but the mechanism of cell death remains unknown. Here we…”
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Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress
Published in Toxicology and applied pharmacology (01-06-2012)“…Nanotechnologies are emerging as highly promising technologies in many sectors in the society. However, the increasing use of engineered nanomaterials also…”
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Classification Framework for Graphene-Based Materials
Published in Angewandte Chemie International Edition (21-07-2014)“…Graphing graphene: Because the naming of graphene‐based materials (GBMs) has led to confusion and inconsistency, a classification approach is necessary. Three…”
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A Biodegradable Multifunctional Graphene Oxide Platform for Targeted Cancer Therapy
Published in Advanced functional materials (01-09-2019)“…The design of multifunctional materials able to both selectively deliver a drug into cells in a targeted manner and display an enhanced propensity for…”
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Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study
Published in Scientific reports (13-03-2019)“…Systems biology is increasingly being applied in nanosafety research for observing and predicting the biological perturbations inflicted by exposure to…”
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Graphene and the Immune System: A Romance of Many Dimensions
Published in Frontiers in immunology (13-06-2017)“…Graphene-based materials (GBMs) are emerging as attractive materials for biomedical applications. Understanding how these materials are perceived by and…”
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