Search Results - "Factor, C."

Induction of myelinating oligodendrocytes in human cortical spheroids by Madhavan, Mayur, Nevin, Zachary S., Shick, H. Elizabeth, Garrison, Eric, Clarkson-Paredes, Cheryl, Karl, Molly, Clayton, Benjamin L. L., Factor, Daniel C., Allan, Kevin C., Barbar, Lilianne, Jain, Tanya, Douvaras, Panagiotis, Fossati, Valentina, Miller, Robert H., Tesar, Paul J.

“…Cerebral organoids provide an accessible system for investigations of cellular composition, interactions, and organization but have lacked oligodendrocytes,…”
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Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells by Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J

“…Two studies show direct conversion of mouse embryonic fibroblasts to oligodendrocyte progenitor cells capable of generating myelinating oligodendrocytes…”
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Epigenomic Comparison Reveals Activation of “Seed” Enhancers during Transition from Naive to Primed Pluripotency by Factor, Daniel C., Corradin, Olivia, Zentner, Gabriel E., Saiakhova, Alina, Song, Lingyun, Chenoweth, Josh G., McKay, Ronald D., Crawford, Gregory E., Scacheri, Peter C., Tesar, Paul J.

“…Naive mouse embryonic stem cells (mESCs) and primed epiblast stem cells (mEpiSCs) represent successive snapshots of pluripotency during embryogenesis. Using…”
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Transcription elongation factors represent in vivo cancer dependencies in glioblastoma by Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Hemann, Michael T., Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N.

“…An in vivo RNA interference screening strategy in glioblastoma enabled the identification of a host of epigenetic targets required for glioblastoma cell…”
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RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation by Xie, Qi, Wu, Qiulian, Kim, Leo, Miller, Tyler E, Liau, Brian B, Mack, Stephen C, Yang, Kailin, Factor, Daniel C, Fang, Xiaoguang, Huang, Zhi, Zhou, Wenchao, Alazem, Kareem, Wang, Xiuxing, Bernstein, Bradley E, Bao, Shideng, Rich, Jeremy N

“…Glioblastomas co-opt stem cell regulatory pathways to maintain brain tumor-initiating cells (BTICs), also known as cancer stem cells. NOTCH signaling has been…”
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NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer by Gotoh, Hitoshi, Wood, William M., Patel, Kiran D., Factor, Daniel C., Boshans, Linda L., Nomura, Tadashi, Tesar, Paul J., Ono, Katsuhiko, Nishiyama, Akiko

“…NG2 is a type 1 integral membrane glycoprotein encoded by the Cspg4 gene. It is expressed on glial progenitor cells known as NG2 glial cells or oligodendrocyte…”
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The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming by Boshans, Linda L, Factor, Daniel C, Singh, Vijender, Liu, Jia, Zhao, Chuntao, Mandoiu, Ion, Lu, Q Richard, Casaccia, Patrizia, Tesar, Paul J, Nishiyama, Akiko

“…Oligodendrocyte precursor cells (OPCs), also known as NG2 glia, arise from neural progenitor cells in the embryonic ganglionic eminences that also generate…”
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Short communication: Correlation between within-herd antibody-prevalence and bulk tank milk antibody levels to Mycobacterium avium ssp. paratuberculosis using 2 commercial immunoassays by Pesqueira, M N, Yus, E, Factor, C, Mato, I, Sanjuán, M L, Eiras, C, Arnaiz, I, Diéguez, F J

“…The objective of this study was to determine the correlation between the results obtained with the ELISA technique for antibodies to Mycobacterium avium ssp…”
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Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease by Elitt, Matthew S., Shick, H. Elizabeth, Madhavan, Mayur, Allan, Kevin C., Clayton, Benjamin L.L., Weng, Chen, Miller, Tyler E., Factor, Daniel C., Barbar, Lilianne, Nawash, Baraa S., Nevin, Zachary S., Lager, Angela M., Li, Yan, Jin, Fulai, Adams, Drew J., Tesar, Paul J.

“…Pelizaeus-Merzbacher disease (PMD) is a fatal X-linked disorder caused by loss of myelinating oligodendrocytes and consequent hypomyelination. The underlying…”
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Hyperphosphataemia sensitizes renally impaired rats to the profibrotic effects of gadodiamide by Fretellier, N, Idée, JM, Bruneval, P, Guerret, S, Daubiné, F, Jestin, G, Factor, C, Poveda, N, Dencausse, A, Massicot, F, Laprévote, O, Mandet, C, Bouzian, N, Port, M, Corot, C

“…BACKGROUND AND PURPOSE Hyperphosphataemia is common in patients with nephrogenic systemic fibrosis (NSF). NSF has been linked to administration of gadolinium…”
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Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination by Hubler, Zita, Allimuthu, Dharmaraja, Bederman, Ilya, Elitt, Matthew S., Madhavan, Mayur, Allan, Kevin C., Shick, H. Elizabeth, Garrison, Eric, T. Karl, Molly, Factor, Daniel C., Nevin, Zachary S., Sax, Joel L., Thompson, Matthew A., Fedorov, Yuriy, Jin, Jing, Wilson, William K., Giera, Martin, Bracher, Franz, Miller, Robert H., Tesar, Paul J., Adams, Drew J.

“…Regeneration of myelin is mediated by oligodendrocyte progenitor cells—an abundant stem cell population in the central nervous system (CNS) and the principal…”
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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo by Najm, Fadi J., Madhavan, Mayur, Zaremba, Anita, Shick, Elizabeth, Karl, Robert T., Factor, Daniel C., Miller, Tyler E., Nevin, Zachary S., Kantor, Christopher, Sargent, Alex, Quick, Kevin L., Schlatzer, Daniela M., Tang, Hong, Papoian, Ruben, Brimacombe, Kyle R., Shen, Min, Boxer, Matthew B., Jadhav, Ajit, Robinson, Andrew P., Podojil, Joseph R., Miller, Stephen D., Miller, Robert H., Tesar, Paul J.

“…Two drugs, miconazole and clobetasol, have functions that modulate differentiation of oligodendrocyte progenitor cells directly, enhance remyelination, and…”
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Genetic diversity of bovine viral diarrhea viruses from the Galicia region of Spain by Factor, C., Yus, E., Eiras, C., Sanjuan, M. L., Cerviño, M., Arnaiz, I., Diéguez, F. J.

“…This study examined the frequency and diversity of bovine viral diarrhoea viruses (BVDVs) infecting cattle in Galicia (northwestern Spain). A total of 86 BVDV…”
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Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes by Nevin, Zachary S., Factor, Daniel C., Karl, Robert T., Douvaras, Panagiotis, Laukka, Jeremy, Windrem, Martha S., Goldman, Steven A., Fossati, Valentina, Hobson, Grace M., Tesar, Paul J.

“…Pelizaeus-Merzbacher disease (PMD) is a pediatric disease of myelin in the central nervous system and manifests with a wide spectrum of clinical severities…”
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Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation by Dorel, Ruth, Sun, Dawei, Carruthers, Nicholas, Castanedo, Georgette M., Ung, Peter M.-U., Factor, Daniel C., Li, Tianbo, Baumann, Hannah, Janota, Danielle, Pang, Jodie, Salphati, Laurent, Meklemburg, Robert, Korman, Allison J., Harper, Halie E., Stubblefield, Samantha, Payandeh, Jian, McHugh, Daniel, Lang, Bradley T., Tesar, Paul J., Dere, Edward, Masureel, Matthieu, Adams, Drew J., Volgraf, Matthew, Braun, Marie-Gabrielle

“…The inhibition of emopamil binding protein (EBP), a sterol isomerase within the cholesterol biosynthesis pathway, promotes oligodendrocyte formation, which has…”
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Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS by Factor, Daniel C., Barbeau, Anna M., Allan, Kevin C., Hu, Lucille R., Madhavan, Mayur, Hoang, An T., Hazel, Kathryn E.A., Hall, Parker A., Nisraiyya, Sagar, Najm, Fadi J., Miller, Tyler E., Nevin, Zachary S., Karl, Robert T., Lima, Bruna R., Song, Yanwei, Sibert, Alexandra G., Dhillon, Gursimran K., Volsko, Christina, Bartels, Cynthia F., Adams, Drew J., Dutta, Ranjan, Gallagher, Michael D., Phu, William, Kozlenkov, Alexey, Dracheva, Stella, Scacheri, Peter C., Tesar, Paul J., Corradin, Olivia

“…Multiple sclerosis (MS) is an autoimmune disease characterized by attack on oligodendrocytes within the central nervous system (CNS). Despite widespread use of…”
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Identification of snake species by toxin mass fingerprinting of their venoms by Stöcklin, R, Mebs, D, Boulain, J C, Panchaud, P A, Virelizier, H, Gillard-Factor, C

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Psychometric validity and clinical usefulness of the vineland adaptive behavior scales and the AAMD adaptive behavior scale for an autistic sample by PERRY, A, FACTOR, D. C

“…Two prominent assessment measures of adaptive behavior were compared and evaluated in terms of their psychometric properties and their clinical usefulness for…”
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Child behaviours as stressors: replicating and extending the use of the CARS as a measure of stress: a research note by Freeman, N L, Perry, A, Factor, D C

“…Autistic children represent a source of stress for their parents, but the most appropriate way to measure this stress is not clear. Two studies in the…”
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Effect of Mycobacterium avium subsp. paratuberculosis infection status on culling and calving difficulty in dairy cattle by Mato, I., Pesqueira, N., Factor, C., Sanjuan, M.L., Yus, E., Fouz, R., Arnaiz, I., Camino, F., Diéguez, F.J.

“…The present paper was designed to assess the effect of Mycobacterium avium subsp. paratuberculosis (MAP) infection status (antibody positive vs antibody…”
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