Search Results - "Fack, Fred "

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma by Keunen, Olivier, Johansson, Mikael, Oudin, Anaïs, Sanzey, Morgane, Rahim, Siti A. Abdul, Fack, Fred, Thorsen, Frits, Taxt, Torfinn, Bartos, Michal, Jirik, Radovan, Miletic, Hrvoje, Wang, Jian, Stieber, Daniel, Stuhr, Linda, Moen, Ingrid, Rygh, Cecilie Brekke, Bjerkvig, Rolf, Niclou, Simone P., Klein, George

“…Bevacizumab, an antibody against vascular endothelial growth factor (VEGF), is a promising, yet controversial, drug in human glioblastoma treatment (GBM). Its…”
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Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways by Fack, Fred, Tardito, Saverio, Hochart, Guillaume, Oudin, Anais, Zheng, Liang, Fritah, Sabrina, Golebiewska, Anna, Nazarov, Petr V, Bernard, Amandine, Hau, Ann‐Christin, Keunen, Olivier, Leenders, William, Lund‐Johansen, Morten, Stauber, Jonathan, Gottlieb, Eyal, Bjerkvig, Rolf, Niclou, Simone P

“…Heterozygous mutations in NADP‐dependent isocitrate dehydrogenases (IDH) define the large majority of diffuse gliomas and are associated with hypermethylation…”
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Measles Virus Genotyping by Nucleotide-Specific Multiplex PCR by KREMER, Jacques R, FACK, Fred, OLINGER, Christophe M, MULDERS, Mick N, MULLER, Claude P

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Glioma proteomics: Status and perspectives by Niclou, Simone P., Fack, Fred, Rajcevic, Uros

“…High grade gliomas are the most common brain tumors in adults and their malignant nature makes them the fourth biggest cause of cancer death. Major efforts in…”
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Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas by Fack, Fred, Espedal, Heidi, Keunen, Olivier, Golebiewska, Anna, Obad, Nina, Harter, Patrick N., Mittelbronn, Michel, Bähr, Oliver, Weyerbrock, Astrid, Stuhr, Linda, Miletic, Hrvoje, Sakariassen, Per Ø., Stieber, Daniel, Rygh, Cecilie B., Lund-Johansen, Morten, Zheng, Liang, Gottlieb, Eyal, Niclou, Simone P., Bjerkvig, Rolf

“…Anti-angiogenic therapy in glioblastoma (GBM) has unfortunately not led to the anticipated improvement in patient prognosis. We here describe how human GBM…”
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Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM) by Demeure, Kevin, Fack, Fred, Duriez, Elodie, Tiemann, Katja, Bernard, Amandine, Golebiewska, Anna, Bougnaud, Sébastien, Bjerkvig, Rolf, Domon, Bruno, Niclou, Simone P.

“…Glioblastoma (GBM) is a highly aggressive primary brain tumor with dismal outcome for affected patients. Because of the significant neo-angiogenesis exhibited…”
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Effects of the Endocrine Disruptors Atrazine and PCB 153 on the Protein Expression of MCF-7 Human Cells by Lasserre, Jean-Paul, Fack, Fred, Revets, Dominique, Planchon, Sébastien, Renaut, Jenny, Hoffmann, Lucien, Gutleb, Arno C, Muller, Claude P, Bohn, Torsten

“…Polychlorinated biphenyls (PCBs) and a number of pesticides can act as endocrine disrupting compounds (EDCs). These molecules exhibit hormonal activity in…”
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Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma by Tardito, Saverio, Oudin, Anaïs, Ahmed, Shafiq U., Fack, Fred, Keunen, Olivier, Zheng, Liang, Miletic, Hrvoje, Sakariassen, Per Øystein, Weinstock, Adam, Wagner, Allon, Lindsay, Susan L., Hock, Andreas K., Barnett, Susan C., Ruppin, Eytan, Mørkve, Svein Harald, Lund-Johansen, Morten, Chalmers, Anthony J., Bjerkvig, Rolf, Niclou, Simone P., Gottlieb, Eyal

“…L -Glutamine (Gln) functions physiologically to balance the carbon and nitrogen requirements of tissues. It has been proposed that in cancer cells undergoing…”
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The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status by Johansson, Mikael, Oudin, Anaïs, Tiemann, Katja, Bernard, Amandine, Golebiewska, Anna, Keunen, Olivier, Fack, Fred, Stieber, Daniel, Wang, Baofeng, Hedman, Håkan, Niclou, Simone P

“…Deregulated growth factor signaling is a major driving force in the initiation and progression of glioblastoma. The tumor suppressor and stem cell marker Lrig1…”
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METB-09IDENTIFYING NOVEL VULNERABILITIES IN OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT GLIOMA by Fack, Fred, Hochart, Guillaume, Oudin, Anais, Leenders, William, Gottlieb, Eyal, Bjerkvig, Rolf, Stauber, Jonathan, Niclou, Simone

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Cystathionine-γ-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas by Cano-Galiano, Andrés, Oudin, Anais, Fack, Fred, Allega, Maria-Francesca, Sumpton, David, Martinez-Garcia, Elena, Dittmar, Gunnar, Hau, Ann-Christin, De Falco, Alfonso, Herold-Mende, Christel, Bjerkvig, Rolf, Meiser, Johannes, Tardito, Saverio, Niclou, Simone P

“…Abstract Background Mutations in isocitrate dehydrogenase 1 or 2 (IDH1/2) define glioma subtypes and are considered primary events in gliomagenesis, impacting…”
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Atrazine and PCB 153 and their effects on the proteome of subcellular fractions of human MCF-7 cells by Lasserre, Jean-Paul, Fack, Fred, Serchi, Tommaso, Revets, Dominique, Planchon, Sébastien, Renaut, Jenny, Hoffmann, Lucien, Gutleb, Arno C., Muller, Claude P., Bohn, Torsten

“…Several man-made organic pollutants including polychlorinated biphenyls (PCBs) and several pesticides may exhibit endocrine disrupting (ED) properties. These…”
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FSMP-07. CYSTATHIONINE-Γ-LYASE DRIVES ANTIOXIDANT DEFENSE IN CYSTEINE-RESTRICTED IDH1 MUTANT ASTROCYTOMAS by Cano-Galiano, Andrés, Oudin, Anais, Fack, Fred, Allega, Maria-Francesca, Sumpton, David, Martinez-Garcia, Elena, Dittmar, Gunnar, Hau, Ann-Christin, Herold-Mende, Christel, Bjerkvig, Rolf, Meiser, Johannes, Tardito, Saverio, Niclou, Simone P

“…Abstract Mutations in isocitrate dehydrogenase 1 or 2 (IDH1/2) define glioma subtypes and are considered primary events in gliomagenesis, impacting tumor…”
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Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture by Rajcevic, Uros, Knol, Jaco C, Piersma, Sander, Bougnaud, Sébastien, Fack, Fred, Sundlisaeter, Eirik, Søndenaa, Karl, Myklebust, Reidar, Pham, Thang V, Niclou, Simone P, Jiménez, Connie R

“…Organotypic tumor spheroids, a 3D in vitro model derived from patient tumor material, preserve tissue heterogeneity and retain structural tissue elements, thus…”
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Glioma proteomics: Status and perspectives : Current status of cancer proteomics, how far are we from clinical application by NICLOU, Simone P, FACK, Fred, RAJCEVIC, Uros

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Identification of differentially expressed proteins in curcumin-treated prostate cancer cell lines by Teiten, Marie-Hélène, Gaigneaux, Anthoula, Chateauvieux, Sébastien, Billing, Anja M, Planchon, Sébastien, Fack, Fred, Renaut, Jenny, Mack, Fabienne, Muller, Claude P, Dicato, Mario, Diederich, Marc

“…Due to high prevalence and slow progression of prostate cancer, primary prevention appears to be attractive strategy for its eradication. During the last…”
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Cortisol is a potent modulator of lipopolysaccharide-induced interferon signaling in macrophages by Billing, Anja M, Fack, Fred, Turner, Jonathan D, Muller, Claude P

“…The effects of cortisol (CORT) on resting and lipopolysaccharide (LPS)-activated monocyte-derived THP-1 macrophages were investigated by proteomics…”
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Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG by Navis, Anna C, Niclou, Simone P, Fack, Fred, Stieber, Daniel, van Lith, Sanne, Verrijp, Kiek, Wright, Alan, Stauber, Jonathan, Tops, Bastiaan, Otte-Holler, Irene, Wevers, Ron A, van Rooij, Arno, Pusch, Stefan, von Deimling, Andreas, Tigchelaar, Wikky, van Noorden, Cornelis J F, Wesseling, Pieter, Leenders, William P J

“…Point mutations in genes encoding NADP+-dependent isocitrate dehydrogenases (especially IDH1) are common in lower grade diffuse gliomas and secondary…”
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Low Genetic Diversity despite Hyperendemicity of Hepatitis B Virus Genotype E throughout West Africa by Mulders, Mick N., Venard, Véronique, Njayou, Mounjohou, Edorh, A. Patrick, Bola Oyefolu, Akkeb O., Kehinde, M. O., Muyembe Tamfum, Jean-Jacques, Nébie, Yacouba K., Maïga, Ibrahim, Ammerlaan, Wim, Fack, Fred, Omilabu, Sunday A., le Faou, Alain, Muller, Claude P.

“…Sub-Saharan Africa suffers from an excessively high endemicity of hepatitis B virus (HBV), but little is known about the prevalent genotypes. In this study, we…”
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IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA by Niclou, S. P., Fack, F., Hochart, G., Oudin, A., Leenders, W., Gottlieb, E., Bjerkvig, R., Stauber, J.

“…BACKGROUND: The oncometabolite D-2-hydroxyglutarate (2-HG) is strongly increased in glial tumors presenting a heterozygous point mutation in isocitrate…”
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