Search Results - "Faccini, Julien"
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Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype
Published in Cell death & disease (11-02-2019)“…Vascular smooth muscle cells (VSMCs) are one of the main cellular determinants in arterial pathology. A large body of evidence indicates that death of VSMCs is…”
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Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease
Published in Scientific reports (16-02-2017)“…Coronary artery disease (CAD) is the most prevalent cause of mortality and morbidity worldwide and the number of individuals at risk is increasing. To better…”
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Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids
Published in Oncotarget (17-05-2016)“…Mitophagy is a critical cellular process that selectively targets damaged mitochondria for autophagosomal degradation both under baseline conditions and in…”
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The Multifunctional Sorting Protein PACS-2 Controls Mitophagosome Formation in Human Vascular Smooth Muscle Cells through Mitochondria-ER Contact Sites
Published in Cells (Basel, Switzerland) (25-06-2019)“…Mitochondria-associated ER membranes (MAMs) are crucial for lipid transport and synthesis, calcium exchange, and mitochondrial functions, and they also act as…”
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Immune-mediated thrombotic thrombocytopenic purpura plasma induces calcium- and IgG-dependent endothelial activation: correlations with disease severity
Published in Haematologica (Roma) (01-04-2023)“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by a severe ADAMTS13 deficiency due to the presence of anti-ADAMTS13…”
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MiR-223 and MiR-186 Are Associated with Long-Term Mortality after Myocardial Infarction
Published in Biomolecules (Basel, Switzerland) (01-09-2022)“…Background—The identification and stratification of patients at risk of fatal outcomes after myocardial infarction (MI) is of considerable interest to guide…”
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Antioxidant and Cytoprotective Properties of Polyphenol-Rich Extracts from Antirhea borbonica and Doratoxylon apetalum against Atherogenic Lipids in Human Endothelial Cells
Published in Antioxidants (24-12-2021)“…The endothelial integrity is the cornerstone of the atherogenic process. Low-density lipoprotein (LDL) oxidation occurring within atheromatous plaques leads to…”
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Vascular endothelial-cadherin is involved in endothelial cell detachment during thrombotic thrombocytopenic purpura
Published in Journal of thrombosis and haemostasis (01-10-2024)“…Immune thrombotic thrombocytopenic purpura (i-TTP) is a life-threatening thrombotic microangiopathy linked to ADAMTS-13 deficiency. It has long been assumed…”
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VE-Cadherin is involved in endothelial cell detachment during Thrombotic Thrombocytopenic Purpura
Published in Journal of thrombosis and haemostasis (29-06-2024)“…Immune Thrombotic thrombocytopenic purpura (i-TTP) is a life-threatening thrombotic microangiopathie linked to ADAMTS13 deficiency. It has long been assumed…”
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Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease
Published in Atherosclerosis (01-08-2017)Get full text
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Identification of a miRNA Based-Signature Associated with Acute Coronary Syndrome: Evidence from the FLORINF Study
Published in Journal of clinical medicine (01-06-2020)“…Background: The discovery of novel biomarkers that improve risk prediction models of acute coronary syndrome (ACS) is needed to better identify and stratify…”
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High-density lipoprotein subclass profile and mortality in patients with coronary artery disease: Results from the GENES study
Published in Archives of cardiovascular diseases (01-11-2016)“…Summary Background High-density lipoproteins (HDLs) are highly heterogeneous particles, and the specific contribution of each subclass to the prediction of…”
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0157 : HDL cholesterol subclasses and platelet aggregation in acute myocardial infarction patients and controls
Published in Archives of cardiovascular diseases supplements (01-04-2016)Get full text
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