Search Results - "Facci, Laura"

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron by Skaper, Stephen D, Facci, Laura, Zusso, Morena, Giusti, Pietro

“…Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and…”
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Mast cells, glia and neuroinflammation: partners in crime? by Skaper, Stephen D., Facci, Laura, Giusti, Pietro

“…Summary Glia and microglia in particular elaborate pro‐inflammatory molecules that play key roles in central nervous system (CNS) disorders from neuropathic…”
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Microglia and mast cells: two tracks on the road to neuroinflammation by Skaper, Stephen D., Giusti, Pietro, Facci, Laura

“…ABSTRACT One of the more important recent advances in neuroscience research is the understanding that there is extensive communication between the immune…”
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Synaptic Plasticity, Dementia and Alzheimer Disease by Skaper, Stephen D, Facci, Laura, Zusso, Morena, Giusti, Pietro

“…Neuroplasticity is not only shaped by learning and memory but is also a mediator of responses to neuron attrition and injury (compensatory plasticity). As an…”
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Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons by Skaper, Stephen D., Facci, Laura, Zusso, Morena, Giusti, Pietro

“…The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural…”
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Serum amyloid A primes microglia for ATP-dependent interleukin-1β release by Facci, Laura, Barbierato, Massimo, Zusso, Morena, Skaper, Stephen D, Giusti, Pietro

“…Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A…”
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Neuroinflammation, microglia and mast cells in the pathophysiology of neurocognitive disorders: a review by Skaper, Stephen D, Facci, Laura, Giusti, Pietro

“…Cells of the immune system and the central nervous system are capable of interacting with each other. The former cell populations respond to infection, tissue…”
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Unilateral tactile agnosia as an onset symptom of corticobasal syndrome by Facci, Laura, Basilico, Stefania, Sellitto, Manuela, Gelosa, Giorgio, Gandola, Martina, Bottini, Gabriella

“…Tactile agnosia is the inability to recognize objects via haptic exploration, in the absence of an elementary sensory deficit. Traditionally, it has been…”
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A co-ultramicronized palmitoylethanolamide/luteolin composite mitigates clinical score and disease-relevant molecular markers in a mouse model of experimental autoimmune encephalomyelitis by Contarini, Gabriella, Franceschini, Davide, Facci, Laura, Barbierato, Massimo, Giusti, Pietro, Zusso, Morena

“…Persistent and/or recurrent inflammatory processes are the main factor leading to multiple sclerosis (MS) lesions. The composite ultramicronized…”
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Co-Ultramicronized Palmitoylethanolamide/Luteolin-Induced Oligodendrocyte Precursor Cell Differentiation is Associated With Tyro3 Receptor Upregulation by Facci, Laura, Barbierato, Massimo, Fusco, Mariella, Giusti, Pietro, Zusso, Morena

“…Remyelination in patients with multiple sclerosis frequently fails, especially in the chronic phase of the disease promoting axonal and neuronal degeneration…”
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Fentanyl enhances immune cell response through TLR4/MD-2 complex by Chemello, Chiara, Facci, Laura, Marcolin, Emma, Ramaschi, Giovanni Eugenio, Barbierato, Massimo, Giusti, Pietro, Bolego, Chiara, Zusso, Morena

“…Opioids have been shown to induce neuroinflammation and immune cell activation, that might contribute to some of the opioid side effects, such as…”
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Pre- and Early Post-treatment With Arthrospira platensis (Spirulina) Extract Impedes Lipopolysaccharide-triggered Neuroinflammation in Microglia by Piovan, Anna, Battaglia, Jessica, Filippini, Raffaella, Dalla Costa, Vanessa, Facci, Laura, Argentini, Carla, Pagetta, Andrea, Giusti, Pietro, Zusso, Morena

“…Background: Uncontrolled neuroinflammation and microglia activation lead to cellular and tissue damage contributing to neurodegenerative and neurological…”
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Astrocyte-microglia cooperation in the expression of a pro-inflammatory phenotype by Barbierato, Massimo, Facci, Laura, Argentini, Carla, Marinelli, Carla, Skaper, Stephen D, Giusti, Pietro

“…Glial cells not only serve supportive and nutritive roles for neurons, but also respond to protracted stress and insults by up-regulating inflammatory…”
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Corrigendum: An Inflammation-Centric View of Neurological Disease: Beyond the Neuron by Skaper, Stephen D, Facci, Laura, Zusso, Morena, Giusti, Pietro

“…[This corrects the article DOI: 10.3389/fncel.2018.00072.]…”
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Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death by Cross, Darren A. E., Culbert, Ainsley A., Chalmers, Katy A., Facci, Laura, Skaper, Stephen D., Reith, Alastair D.

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Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages by Bolego, Chiara, Cignarella, Andrea, Giusti, Pietro, Fadini, Gian Paolo, Belluti, Federica, Boscaro, Carlotta, Trenti, Annalisa, Facci, Laura, Zusso, Morena, Tedesco, Serena, Skaper, Stephen D.

“…Several studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide-…”
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Selective small‐molecule inhibitors of glycogen synthase kinase‐3 activity protect primary neurones from death by Cross, Darren A. E., Culbert, Ainsley A., Chalmers, Katy A., Facci, Laura, Skaper, Stephen D., Reith, Alastair D.

“…The phosphatidylinositol 3‐kinase (PI 3‐kinase)/protein kinase B (PKB; also known as Akt) signalling pathway is recognized as playing a central role in the…”
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P2X7 receptors on microglial cells mediate injury to cortical neurons in vitro by Skaper, Stephen D., Facci, Laura, Culbert, Ainsley A., Evans, Nicholas A., Chessell, Iain, Davis, John B., Richardson, Jill C.

“…The P2X7 receptor has been implicated in the release of cytokines and in the induction of cell death, and is up‐regulated in a transgenic mouse model of…”
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MAP kinase pathways in neuronal cell death by Philpott, Karen L, Facci, Laura

“…The signaling pathways which contribute to neuronal death during development, aging and disease have been extensively studied. While initial efforts focused on…”
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Neurotrophins Rescue Cerebellar Granule Neurons from Oxidative Stress‐Mediated Apoptotic Death: Selective Involvement of Phosphatidylinositol 3‐Kinase and the Mitogen‐Activated Protein Kinase Pathway by Skaper, Stephen D., Floreani, Maura, Negro, Alessandro, Facci, Laura, Giusti, Pietro

“…: Cerebellar granule neurons maintained in medium containing serum and 25 mM K+ reliably undergo an apoptotic death when switched to serum‐free medium with 5…”
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