Search Results - "Fabyanic, Emily B"

TET1 facilitates specification of early human lineages including germ cells by Hsu, Fei-Man, Wu, Qiu Ya, Fabyanic, Emily B., Wei, Alex, Wu, Hao, Clark, Amander T.

“…Ten Eleven Translocation 1 (TET1) is a regulator of localized DNA demethylation through the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine…”
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Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase by Schutsky, Emily K, DeNizio, Jamie E, Hu, Peng, Liu, Monica Yun, Nabel, Christopher S, Fabyanic, Emily B, Hwang, Young, Bushman, Frederic D, Wu, Hao, Kohli, Rahul M

“…A bisulfite-free sequencing method yields high-confidence 5hmC profiles in low-input samples. Here we present APOBEC-coupled epigenetic sequencing (ACE-seq), a…”
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Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects by Fabyanic, Emily B., Hu, Peng, Qiu, Qi, Berríos, Kiara N., Connolly, Daniel R., Wang, Tong, Flournoy, Jennifer, Zhou, Zhaolan, Kohli, Rahul M., Wu, Hao

“…Oxidative modification of 5-methylcytosine (5mC) by ten-eleven translocation (TET) DNA dioxygenases generates 5-hydroxymethylcytosine (5hmC), the most abundant…”
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An evaluation of the discriminating power of an Integrated Ballistics Identification System® Heritage™system with the NIST standard cartridge case (Standard Reference Material 2461) by Morris, Keith B., Law, Eric F., Jefferys, Roger L., Dearth, Elizabeth C., Fabyanic, Emily B.

“…•NIST SRM 2461 cartridge cases were used to test the performance of IBIS®.•Minimal inter- and intra-variability within users was observed.•Excellent…”
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In vitro cytotoxicity assessment of a West Virginia chemical spill mixture involving 4-methylcyclohexanemethanol and propylene glycol phenyl ether by Han, Alice A., Fabyanic, Emily B., Miller, Julie V., Prediger, Maren S., Prince, Nicole, Mouch, Julia A., Boyd, Jonathan

“…Thousands of gallons of industrial chemicals, crude 4-methylcyclohexanemethanol (MCHM) and propylene glycol phenyl ether (PPh), leaked from industrial tanks…”
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Spatiotemporal phosphoprotein distribution and associated cytokine response of a traumatic injury by Han, Alice A., Currie, Holly N., Loos, Matthew S., Vrana, Julie A., Fabyanic, Emily B., Prediger, Maren S., Boyd, Jonathan W.

“…•Spatiotemporal gradient of phosphoproteins is observed following a traumatic injury.•Phosphorylation is correlated to cytokine production following a…”
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Development of Single-Cell Transcriptomic & Epigenomic Sequencing Technologies to Assess Cell-Type-Specific Gene Regulatory Programs in Mammalian Brains by Fabyanic, Emily B

“…Recent efforts to develop single-cell technologies have played a pivotal role in our ability to gain a high-resolution understanding of how tissue…”
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