Search Results - "Fabrizi, Cinzia"

mTOR-Related Cell-Clearing Systems in Epileptic Seizures, an Update by Limanaqi, Fiona, Biagioni, Francesca, Busceti, Carla Letizia, Fabrizi, Cinzia, Frati, Alessandro, Fornai, Francesco

“…Recent evidence suggests that autophagy impairment is implicated in the epileptogenic mechanisms downstream of mTOR hyperactivation. This holds true for a…”
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Thrombin in peripheral nerves: friend or foe? by Pompili, Elena, Fabrizi, Cinzia

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Potential Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea by Limanaqi, Fiona, Biagioni, Francesca, Busceti, Carla Letizia, Polzella, Maico, Fabrizi, Cinzia, Fornai, Francesco

“…Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from…”
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The Mechanisms Mediated by α7 Acetylcholine Nicotinic Receptors May Contribute to Peripheral Nerve Regeneration by Salazar Intriago, Michael Sebastian, Piovesana, Roberta, Matera, Alessandro, Taggi, Marilena, Canipari, Rita, Fabrizi, Cinzia, Papotto, Claudio, Matera, Carlo, De Amici, Marco, Dallanoce, Clelia, Tata, Ada Maria

“…Due to the microenvironment created by Schwann cell (SC) activity, peripheral nerve fibers are able to regenerate. Inflammation is the first response to nerve…”
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Quantitative Ultrastructural Morphometry and Gene Expression of mTOR-Related Mitochondriogenesis within Glioblastoma Cells by Ferese, Rosangela, Lenzi, Paola, Fulceri, Federica, Biagioni, Francesca, Fabrizi, Cinzia, Gambardella, Stefano, Familiari, Pietro, Frati, Alessandro, Limanaqi, Fiona, Fornai, Francesco

“…In glioblastoma (GBM) cells, an impairment of mitochondrial activity along with autophagy suppression occurs. Autophagy suppression in GBM promotes stemness,…”
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Norepinephrine Protects against Methamphetamine Toxicity through β2-Adrenergic Receptors Promoting LC3 Compartmentalization by Lazzeri, Gloria, Busceti, Carla L, Biagioni, Francesca, Fabrizi, Cinzia, Morucci, Gabriele, Giorgi, Filippo S, Ferrucci, Michela, Lenzi, Paola, Puglisi-Allegra, Stefano, Fornai, Francesco

“…Norepinephrine (NE) neurons and extracellular NE exert some protective effects against a variety of insults, including methamphetamine (Meth)-induced cell…”
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Protease Activated Receptor 1 and Its Ligands as Main Regulators of the Regeneration of Peripheral Nerves by Pompili, Elena, De Franchis, Valerio, Giampietri, Claudia, Leone, Stefano, De Santis, Elena, Fornai, Francesco, Fumagalli, Lorenzo, Fabrizi, Cinzia

“…In contrast with the brain and spinal cord, peripheral nerves possess a striking ability to regenerate after damage. This characteristic of the peripheral…”
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Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier by Pompili, Elena, Ciraci, Viviana, Leone, Stefano, De Franchis, Valerio, Familiari, Pietro, Matassa, Roberto, Familiari, Giuseppe, Tata, Ada Maria, Fumagalli, Lorenzo, Fabrizi, Cinzia

“…Schwann cells (SC) are characterized by a remarkable plasticity that enables them to promptly respond to nerve injury promoting axonal regeneration. In…”
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Cholangiocarcinoma Malignant Traits Are Promoted by Schwann Cells through TGFβ Signaling in a Model of Perineural Invasion by de Franchis, Valerio, Petrungaro, Simonetta, Pizzichini, Elisa, Camerini, Serena, Casella, Marialuisa, Somma, Francesca, Mandolini, Enrico, Carpino, Guido, Overi, Diletta, Cardinale, Vincenzo, Facchiano, Antonio, Filippini, Antonio, Gaudio, Eugenio, Fabrizi, Cinzia, Giampietri, Claudia

“…The term cholangiocarcinoma (CCA) defines a class of epithelial malignancies originating from bile ducts. Although it has been demonstrated that CCA patients…”
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Protease-Activated Receptor–1 Expression in Rat Microglia after Trimethyltin Treatment by Pompili, Elena, Fabrizi, Cinzia, Nori, Stefania Lucia, Panetta, Barbara, Geloso, Maria Concetta, Corvino, Valentina, Michetti, Fabrizio, Fumagalli, Lorenzo

“…In the nervous system, protease-activated receptors (PARs), which are activated by thrombin and other extracellular proteases, are expressed widely at both…”
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Specific Disruption of a Schwann Cell Dystrophin-Related Protein Complex in a Demyelinating Neuropathy by Sherman, Diane L, Fabrizi, Cinzia, Gillespie, C.Stewart, Brophy, Peter J

“…Dystroglycan-dystrophin complexes are believed to have structural and signaling functions by linking extracellular matrix proteins to the cytoskeleton and…”
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Lithium Improves Survival of PC12 Pheochromocytoma Cells in High-Density Cultures and after Exposure to Toxic Compounds by Fornai, Francesco, Fumagalli, Lorenzo, Fabrizi, Cinzia, Lenzi, Paola, Leone, Stefano, Catizone, Angela, De Vito, Stefania, Somma, Francesca, Pompili, Elena

“…Autophagy is an evolutionary conserved mechanism that allows for the degradation of long-lived proteins and entire organelles which are driven to lysosomes for…”
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Rab11A Depletion in Microglia-Derived Extracellular Vesicle Proteome upon Beta-Amyloid Treatment by Mignogna, Giuseppina, Fabrizi, Cinzia, Correani, Virginia, Giorgi, Alessandra, Maras, Bruno

“…Microglia, the macrophage-like glial cells, behave as sentinels against exogenous pathogens invading the neural tissue. Their commitment is not only confined…”
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Autophagy in trimethyltin-induced neurodegeneration by Pompili, Elena, Fabrizi, Cinzia, Fumagalli, Lorenzo, Fornai, Francesco

“…Autophagy is a degradative process playing an important role in removing misfolded or aggregated proteins, clearing damaged organelles, such as mitochondria…”
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Role of the protease-activated receptor 1 in regulating the function of glial cells within central and peripheral nervous system by Pompili, Elena, Fabrizi, Cinzia, Fornai, Francesco, Fumagalli, Lorenzo

“…Protease-activated receptor 1 (PAR1) is a cell surface receptor, which belongs to a family of G protein-coupled receptors and signals in response to multiple…”
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Transient expression of the neurofilament proteins NF-L and NF-M by Schwann cells is regulated by axonal contact by Fabrizi, Cinzia, Kelly, Bernadette M., Gillespie, C. Stewart, Schlaepfer, William W., Scherer, Steven S., Brophy, Peter J.

“…Expression of the genes that encode neurofilament proteins is considered to be confined normally to neurons. However, in demyelinating peripheral nerves…”
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Plasma Membrane Protein Profiling in Beta‐Amyloid‐Treated Microglia Cell Line by Correani, Virginia, Di Francesco, Laura, Mignogna, Giuseppina, Fabrizi, Cinzia, Leone, Stefano, Giorgi, Alessandra, Passeri, Alessia, Casata, Roberto, Fumagalli, Lorenzo, Maras, Bruno, Schininà, M.Eugenia

“…In the responsiveness of microglia to toxic stimuli, plasma membrane proteins play a key role. In this study we treated with a synthetic beta amyloid peptide…”
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Acetylation and phosphorylation of STAT3 are involved in the responsiveness of microglia to beta amyloid by Eufemi, Margherita, Cocchiola, Rossana, Romaniello, Donatella, Correani, Virginia, Di Francesco, Laura, Fabrizi, Cinzia, Maras, Bruno, Schininà, M. Eugenia

“…•A phosphorylated STAT3 species marks microglia activation at 4 h by Aβ peptide.•Activation of STAT3 signalling in activated microglia is dependent from…”
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PAR1 activation affects the neurotrophic properties of Schwann cells by Pompili, Elena, Fabrizi, Cinzia, Somma, Francesca, Correani, Virginia, Maras, Bruno, Schininà, Maria Eugenia, Ciraci, Viviana, Artico, Marco, Fornai, Francesco, Fumagalli, Lorenzo

“…Protease-activated receptor-1 (PAR1) is the prototypic member of a family of four G-protein-coupled receptors that signal in response to extracellular…”
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Lithium limits trimethyltin‐induced cytotoxicity and proinflammatory response in microglia without affecting the concurrent autophagy impairment by Fabrizi, Cinzia, Pompili, Elena, Somma, Francesca, De Vito, Stefania, Ciraci, Viviana, Artico, Marco, Lenzi, Paola, Fornai, Francesco, Fumagalli, Lorenzo

“…Trimethyltin (TMT) is a highly toxic molecule present as an environmental contaminant causing neurodegeneration particularly of the limbic system both in…”
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