Search Results - "Fabris, Sonia"

The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression by Bee, Leonardo, Fabris, Sonia, Cherubini, Roberto, Mognato, Maddalena, Celotti, Lucia

“…This study investigated the efficiency of Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR) repair systems in rejoining DNA double-strand…”
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Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma by Lionetti, Marta, Biasiolo, Marta, Agnelli, Luca, Todoerti, Katia, Mosca, Laura, Fabris, Sonia, Sales, Gabriele, Deliliers, Giorgio Lambertenghi, Bicciato, Silvio, Lombardi, Luigia, Bortoluzzi, Stefania, Neri, Antonino

“…To date, little evidence of miRNA expression/deregulation in multiple myeloma has been reported. To characterize miRNA in the context of the major multiple…”
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The Role of New Technologies in Myeloproliferative Neoplasms by Palumbo, Giuseppe A, Stella, Stefania, Pennisi, Maria Stella, Pirosa, Cristina, Fermo, Elisa, Fabris, Sonia, Cattaneo, Daniele, Iurlo, Alessandra

“…The hallmark of -negative myeloproliferative neoplasms (MPNs) is the presence of a driver mutation in , or gene. These genetic alterations represent a key…”
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Real-life monocentric experience of venetoclax-based regimens for acute myeloid leukemia by Sciumè, Mariarita, Bosi, Alessandro, Canzi, Marta, Ceparano, Giusy, Serpenti, Fabio, De Roberto, Pasquale, Fabris, Sonia, Tagliaferri, Elena, Cavallaro, Francesca, Onida, Francesco, Fracchiolla, Nicola Stefano

“…Combination of venetoclax and hypomethylating agents (HMAs) has become a standard of care in acute myeloid leukemia (AML) aged >75 years or who have…”
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Target Therapies for Systemic Mastocytosis: An Update by Sciumè, Mariarita, De Magistris, Claudio, Galli, Nicole, Ferretti, Eleonora, Milesi, Giulia, De Roberto, Pasquale, Fabris, Sonia, Grifoni, Federica Irene

“…Systemic mastocytosis (SM) results from a clonal proliferation of abnormal mast cells (MCs) in extra-cutaneous organs. It could be divided into indolent SM,…”
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Circulating tumor DNA as a liquid biopsy in plasma cell dyscrasias by Gerber, Bernhard, Manzoni, Martina, Spina, Valeria, Bruscaggin, Alessio, Lionetti, Marta, Fabris, Sonia, Barbieri, Marzia, Ciceri, Gabriella, Pompa, Alessandra, Forestieri, Gabriela, Lerch, Erika, Servida, Paolo, Bertoni, Francesco, Zucca, Emanuele, Ghielmini, Michele, Cortelezzi, Agostino, Cavalli, Franco, Stussi, Georg, Baldini, Luca, Rossi, Davide, Neri, Antonino

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Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study by Cattaneo, Daniele, Croci, Giorgio Alberto, Bucelli, Cristina, Tabano, Silvia, Cannone, Marta Giulia, Gaudioso, Gabriella, Barbanti, Maria Chiara, Barbullushi, Kordelia, Bianchi, Paola, Fermo, Elisa, Fabris, Sonia, Baldini, Luca, Gianelli, Umberto, Iurlo, Alessandra

“…Lack of demonstrable mutations affecting , or driver genes within the spectrum of -negative myeloproliferative neoplasms (MPNs) is currently referred to as a…”
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Single-Cell RNA Sequencing for the Detection of Clonotypic V(D)J Rearrangements in Multiple Myeloma by Matera, Antonio, Marella, Alessio, Maeda, Akihiro, Da Vià, Matteo C, Lazzaroni, Francesca, Fabris, Sonia, Pioggia, Stefania, Porretti, Laura, Colombo, Federico, Torricelli, Federica, Neri, Antonino, Taiana, Elisa, Fabbiano, Giuseppina, Traini, Valentina, Genuardi, Elisa, Drandi, Daniela, Bolli, Niccolò, Lionetti, Marta

“…Multiple myeloma (MM) has a highly heterogeneous genetic background, which complicates its molecular tracking over time. Nevertheless, each MM patient's…”
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Case Report: Evolution of KIT D816V-Positive Systemic Mastocytosis to Myeloid Neoplasm With PDGFRA Rearrangement Responsive to Imatinib by Sciumè, Mariarita, Ceparano, Giusy, Eller-Vainicher, Cristina, Fabris, Sonia, Lonati, Silvia, Croci, Giorgio Alberto, Baldini, Luca, Grifoni, Federica Irene

“…Systemic mastocytosis (SM) is a rare neoplasm resulting from extracutaneous infiltration of clonal mast cells (MC). The clinical features of SM are very…”
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A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: An integrated genomics approach reveals a wide gene dosage effect by Agnelli, Luca, Mosca, Laura, Fabris, Sonia, Lionetti, Marta, Andronache, Adrian, Kwee, Ivo, Todoerti, Katia, Verdelli, Donata, Battaglia, Cristina, Bertoni, Francesco, Deliliers, Giorgio Lambertenghi, Neri, Antonino

“…Multiple myeloma (MM) is characterized by marked genomic heterogeneity. Beyond structural rearrangements, a relevant role in its biology is represented by…”
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A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias by Lionetti, Marta, Barbieri, Marzia, Todoerti, Katia, Agnelli, Luca, Fabris, Sonia, Tonon, Giovanni, Segalla, Simona, Cifola, Ingrid, Pinatel, Eva, Tassone, Pierfrancesco, Musto, Pellegrino, Baldini, Luca, Neri, Antonino

“…DIS3 is a catalytic subunit of the human exosome complex, containing exonucleolytic (RNB) and endonucleolytic (PIN) domains, recently found mutated in multiple…”
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Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia by Hoxha, Mirjam, Fabris, Sonia, Agnelli, Luca, Bollati, Valentina, Cutrona, Giovanna, Matis, Serena, Recchia, Anna Grazia, Gentile, Massimo, Cortelezzi, Agostino, Morabito, Fortunato, Bertazzi, Pier Alberto, Ferrarini, Manlio, Neri, Antonino

“…Several studies have proposed telomere length and telomerase activity as prognostic factors in chronic lymphocytic leukemia (CLL), whereas information…”
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Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns by Cifola, Ingrid, Lionetti, Marta, Pinatel, Eva, Todoerti, Katia, Mangano, Eleonora, Pietrelli, Alessandro, Fabris, Sonia, Mosca, Laura, Simeon, Vittorio, Petrucci, Maria Teresa, Morabito, Fortunato, Offidani, Massimo, Di Raimondo, Francesco, Falcone, Antonietta, Caravita, Tommaso, Battaglia, Cristina, De Bellis, Gianluca, Palumbo, Antonio, Musto, Pellegrino, Neri, Antonino

“…Primary plasma cell leukemia (pPCL) is a rare and aggressive form of plasma cell dyscrasia and may represent a valid model for high-risk multiple myeloma (MM)…”
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Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia by Ronchetti, Domenica, Mosca, Laura, Cutrona, Giovanna, Tuana, Giacomo, Gentile, Massimo, Fabris, Sonia, Agnelli, Luca, Ciceri, Gabriella, Matis, Serena, Massucco, Carlotta, Colombo, Monica, Reverberi, Daniele, Recchia, Anna Grazia, Bossio, Sabrina, Negrini, Massimo, Tassone, Pierfrancesco, Morabito, Fortunato, Ferrarini, Manlio, Neri, Antonino

“…Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs are non-coding RNAs involved in the maturation of other RNA molecules. Alterations of…”
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Anagrelide and Mutational Status in Essential Thrombocythemia by Iurlo, Alessandra, Cattaneo, Daniele, Orofino, Nicola, Bucelli, Cristina, Fabris, Sonia, Cortelezzi, Agostino

“…Background Anagrelide is an orally active, quinazolone-derived, platelet-lowering agent that acts by blocking megakaryocyte maturation and polyploidization as…”
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Lymphocyte Doubling Time As A Key Prognostic Factor To Predict Time To First Treatment In Early-Stage Chronic Lymphocytic Leukemia by Morabito, Fortunato, Tripepi, Giovanni, Moia, Riccardo, Recchia, Anna Grazia, Boggione, Paola, Mauro, Francesca Romana, Bossio, Sabrina, D’Arrigo, Graziella, Martino, Enrica Antonia, Vigna, Ernesto, Storino, Francesca, Fronza, Gilberto, Di Raimondo, Francesco, Rossi, Davide, Condoluci, Adalgisa, Colombo, Monica, Fais, Franco, Fabris, Sonia, Foa, Robin, Cutrona, Giovanna, Gentile, Massimo, Montserrat, Emili, Gaidano, Gianluca, Ferrarini, Manlio, Neri, Antonino

“…The prognostic role of lymphocyte doubling time (LDT) in chronic lymphocytic leukemia (CLL) was recognized more than three decades ago when the neoplastic…”
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Clinical, Morphological and Clonal Progression of VEXAS Syndrome in the Context of Myelodysplasia Treated with Azacytidine by Manzoni, Marco, Bosi, Alessandro, Fabris, Sonia, Lionetti, Marta, Salerio, Simone, Migliorini, Anna Chiara, Cavallaro, Francesca, Barbullushi, Kordelia, Rampi, Nicolò, Montefusco, Vittorio, Alessio, Maria Grazia, Neri, Antonino, Baldini, Luca, Sciumè, Mariarita, Tagliaferri, Elena, Fracchiolla, Nicola, Bolli, Niccolò

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Limits and Applications of Genomic Analysis of Circulating Tumor DNA as a Liquid Biopsy in Asymptomatic Forms of Multiple Myeloma by Manzoni, Martina, Pompa, Alessandra, Fabris, Sonia, Pelizzoni, Francesca, Ciceri, Gabriella, Seia, Manuela, Ziccheddu, Bachisio, Bolli, Niccolò, Corradini, Paolo, Baldini, Luca, Neri, Antonino, Lionetti, Marta

“…Supplemental Digital Content is available in the text…”
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An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma by Ronchetti, Domenica, Lionetti, Marta, Mosca, Laura, Agnelli, Luca, Andronache, Adrian, Fabris, Sonia, Deliliers, Giorgio Lambertenghi, Neri, Antonino

“…The role of microRNAs (miRNAs) in multiple myeloma (MM) has yet to be fully elucidated. To identify miRNAs that are potentially deregulated in MM, we…”
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Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia by Maura, Francesco, Mosca, Laura, Fabris, Sonia, Cutrona, Giovanna, Matis, Serena, Lionetti, Marta, Agnelli, Luca, Barbieri, Marzia, D'Anca, Marianna, Manzoni, Martina, Colombo, Monica, Massucco, Carlotta, Reverberi, Daniele, Gentile, Massimo, Recchia, Anna Grazia, Bossio, Sabrina, Ilariucci, Fiorella, Musolino, Caterina, Di Raimondo, Francesco, Cortelezzi, Agostino, Morabito, Fortunato, Ferrarini, Manlio, Neri, Antonino

“…IGF1R is emerging as an important gene in the pathogenesis of many solid and haematological cancers and its over-expression has been reported as frequently…”
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