Search Results - "Fabricio Alves da Silva"

Characterization of a SPM-1 metallo-beta-lactamase-producing Pseudomonas aeruginosa by comparative genomics and phenotypic analysis by do Nascimento, Ana Paula Barbosa, Medeiros Filho, Fernando, Pauer, Heidi, Antunes, Luis Caetano Martha, Sousa, Hério, Senger, Hermes, Albano, Rodolpho Mattos, Trindade dos Santos, Marcelo, Carvalho-Assef, Ana Paula D’Alincourt, da Silva, Fabrício Alves Barbosa

“…Pseudomonas aeruginosa is one of the most common pathogens related to healthcare-associated infections. The Brazilian isolate, named CCBH4851, is a…”
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Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine by Conforte, Alessandra J., Tuszynski, Jack Adam, Silva, Fabricio Alves Barbosa da, Carels, Nicolas

“…Traditional approaches to cancer therapy seek common molecular targets in tumors from different patients. However, molecular profiles differ between patients,…”
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Suspected Adverse Drug Reactions Related to Breast Cancer Chemotherapy: Disproportionality Analysis of the Brazilian Spontaneous Reporting System by Barcelos, Flávia Campos, de Matos, Guacira Corrêa, da Silva, Mario Jorge Sobreira, da Silva, Fabrício Alves Barbosa, Lima, Elisangela da Costa

“…Spontaneous reporting systems may generate a large volume of information in real world conditions with a relatively low cost. Disproportionality measures are…”
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FindTargetsWEB: A User-Friendly Tool for Identification of Potential Therapeutic Targets in Metabolic Networks of Bacteria by Merigueti, Thiago Castanheira, Carneiro, Marcia Weber, Carvalho-Assef, Ana Paula D'A, Silva-Jr, Floriano Paes, da Silva, Fabricio Alves Barbosa

“…Healthcare-associated infections (HAIs) are a serious public health problem. They can be associated with morbidity and mortality and are responsible for the…”
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Data-Driven Modeling of Breast Cancer Tumors Using Boolean Networks by Sgariglia, Domenico, Conforte, Alessandra Jordano, Pedreira, Carlos Eduardo, Vidal de Carvalho, Luis Alfredo, Carneiro, Flavia Raquel Gonçalves, Carels, Nicolas, Silva, Fabricio Alves Barbosa da

“…Cancer is a genomic disease involving various intertwined pathways with complex cross-communication links. Conceptually, this complex interconnected system…”
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Serious Adverse Drug Reactions and Safety Signals in Children: A Nationwide Database Study by Vieira, Jean Mendes de Lucena, de Matos, Guacira Corrêa, da Silva, Fabrício Alves Barbosa, Bracken, Louise E., Peak, Matthew, Lima, Elisangela da Costa

“…Children are more exposed to inappropriate medicine use and its consequent harms. Spontaneous reporting of suspected Serious Adverse Drug Reactions (SADR)…”
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A Strategy Utilizing Protein-Protein Interaction Hubs for the Treatment of Cancer Diseases by Carels, Nicolas, Sgariglia, Domenico, Junior, Marcos Guilherme Vieira, Lima, Carlyle Ribeiro, Carneiro, Flávia Raquel Gonçalves, Silva, Gilberto Ferreira da, Silva, Fabricio Alves Barbosa da, Scardini, Rafaela, Tuszynski, Jack Adam, Andrade, Cecilia Vianna de, Monteiro, Ana Carolina, Martins, Marcel Guimarães, Silva, Talita Goulart da, Ferraz, Helen, Finotelli, Priscilla Vanessa, Balbino, Tiago Albertini, Pinto, José Carlos

“…We describe a strategy for the development of a rational approach of neoplastic disease therapy based on the demonstration that scale-free networks are…”
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Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa by Medeiros Filho, Fernando, do Nascimento, Ana Paula Barbosa, Dos Santos, Marcelo Trindade, Carvalho-Assef, Ana Paula D'Alincourt, da Silva, Fabricio Alves Barbosa

“…Healthcare-associated infections caused by bacteria such as Pseudomonas aeruginosa are a major public health problem worldwide. Gene regulatory networks (GRN)…”
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Editorial: Big Data and machine learning in cancer theranostics by Silva, Fabricio Alves Barbosa da, Tuszynski, Jack Adam, Nakaya, Helder, Paller, Channing J.

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Detection of potential safety signals related to the use of remdesivir and tocilizumab in the COVID era during pregnancy, resorting to open data from the FDA adverse event reporting system (FAERS) by Romão, Beatriz Marinho Silva, Duval, Felipe Vieira, Lima, Elisângela Costa, da Silva, Fabrício Alves Barbosa, de Matos, Guacira Correa

“…The in-hospital treatment for COVID-19 may include medicines from various therapeutic classes, such as antiviral remdesivir and immunosuppressant tocilizumab…”
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Pulmonary Mesenchymal Stem Cells in Mild Cases of COVID-19 Are Dedicated to Proliferation; In Severe Cases, They Control Inflammation, Make Cell Dispersion, and Tissue Regeneration by Henriques-Pons, Andrea, Beghini, Daniela Gois, Silva, Vanessa Dos Santos, Iwao Horita, Samuel, da Silva, Fabrício Alves Barbosa

“…Mesenchymal stem cells (MSCs) are multipotent adult stem cells present in virtually all tissues; they have potent self-renewal capacity and differentiate into…”
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Modeling Basins of Attraction for Breast Cancer Using Hopfield Networks by Conforte, Alessandra Jordano, Alves, Leon, Coelho, Flávio Codeço, Carels, Nicolas, da Silva, Fabrício Alves Barbosa

“…Cancer is a genetic disease for which traditional treatments cause harmful side effects. After two decades of genomics technological breakthroughs,…”
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Optimizing therapeutic targets for breast cancer using boolean network models by Sgariglia, Domenico, Carneiro, Flavia Raquel Gonçalves, Vidal de Carvalho, Luis Alfredo, Pedreira, Carlos Eduardo, Carels, Nicolas, da Silva, Fabricio Alves Barbosa

“…Studying gene regulatory networks associated with cancer provides valuable insights for therapeutic purposes, given that cancer is fundamentally a genetic…”
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A Systematic Strategy to Find Potential Therapeutic Targets for Pseudomonas aeruginosa Using Integrated Computational Models by Medeiros Filho, Fernando, Nascimento, Ana Paula Barbosa do, Costa, Maiana de Oliveira Cerqueira e, Merigueti, Thiago Castanheira, Menezes, Marcio Argollo de, Nicolás, Marisa Fabiana, Santos, Marcelo Trindade dos, Carvalho-Assef, Ana Paula D’Alincourt, Silva, Fabrício Alves Barbosa da

“…Pseudomonas aeruginosa is an opportunistic human pathogen that has been a constant global health problem due to its ability to cause infection at different…”
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Mining in Twitter for adverse events from malaria drugs: the case of doxycycline by Duval, Felipe Vieira, Silva, Fabrício Alves Barbosa da

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Case Studies of Attacks over Adaptive Modulation Based Tactical Software Defined Radios by Moura, David Fernandes Cruz, da Silva, Fabricio Alves Barbosa, Galdino, Juraci Ferreira

“…This paper presents case studies of attacks aimed at tactical software defined radios based on a classification with the most common sources of…”
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Boolean model of the gene regulatory network of Pseudomonas aeruginosa CCBH4851 by Chagas, Márcia da Silva, Trindade Dos Santos, Marcelo, Argollo de Menezes, Marcio, da Silva, Fabricio Alves Barbosa

“…infections are one of the leading causes of death in immunocompromised patients with cystic fibrosis, diabetes, and lung diseases such as pneumonia and…”
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A Data Science Approach for the Identification of Molecular Signatures of Aggressive Cancers by Barbosa-Silva, Adriano, Magalhães, Milena, Da Silva, Gilberto Ferreira, Da Silva, Fabricio Alves Barbosa, Carneiro, Flávia Raquel Gonçalves, Carels, Nicolas

“…The main hallmarks of cancer include sustaining proliferative signaling and resisting cell death. We analyzed the genes of the WNT pathway and seven…”
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An updated gene regulatory network reconstruction of multidrug-resistant Pseudomonas aeruginosa CCBH4851 by Chagas, Márcia da Silva, Medeiros Filho, Fernando, Santos, Marcelo Trindade dos, Menezes, Marcio Argollo de, Carvalho-Assef, Ana Paula D’Alincourt, Silva, Fabricio Alves Barbosa da

“…BACKGROUNDHealthcare-associated infections due to multidrug-resistant (MDR) bacteria such as Pseudomonas aeruginosa are significant public health issues…”
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Potential safety signals for antibacterial agents from the Brazilian national pharmacovigilance database (Vigimed/VigiFlow) by Barbosa, Luiza Hoehl Loureiro Alves, Silva, Alice Ramos Oliveira, Carvalho-Assef, Ana Paula D'Alincourt, Lima, Elisangela Costa, da Silva, Fabricio Alves Barbosa

“…Antibacterial drugs are a widely used drug class due to the frequency of infectious diseases globally. Risks knowledge should ground these medicines'…”
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