Search Results - "Fabio Bagnoli"

The role of vaccines in combatting antimicrobial resistance by Micoli, Francesca, Bagnoli, Fabio, Rappuoli, Rino, Serruto, Davide

“…The use of antibiotics has enabled the successful treatment of bacterial infections, saving the lives and improving the health of many patients worldwide…”
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Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies by Clegg, Jonah, Soldaini, Elisabetta, McLoughlin, Rachel M, Rittenhouse, Stephen, Bagnoli, Fabio, Phogat, Sanjay

“…is one of the most important human pathogens worldwide. Its high antibiotic resistance profile reinforces the need for new interventions like vaccines in…”
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Staphylococcal Esx proteins modulate apoptosis and release of intracellular Staphylococcus aureus during infection in epithelial cells by Korea, Charalampia G, Balsamo, Giuliana, Pezzicoli, Alfredo, Merakou, Christina, Tavarini, Simona, Bagnoli, Fabio, Serruto, Davide, Unnikrishnan, Meera

“…The opportunistic pathogen Staphylococcus aureus is one of the major causes of health care-associated infections. S. aureus is primarily an extracellular…”
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Inferring reasons for the failure of Staphylococcus aureus vaccines in clinical trials by Bagnoli, Fabio, Bertholet, Sylvie, Grandi, Guido

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Staphylococcus aureus -Specific Tissue-Resident Memory CD4 + T Cells Are Abundant in Healthy Human Skin by Hendriks, Astrid, Mnich, Malgorzata Ewa, Clemente, Bruna, Cruz, Ana Rita, Tavarini, Simona, Bagnoli, Fabio, Soldaini, Elisabetta

“…The skin is an immunocompetent tissue that harbors several kinds of immune cells and a plethora of commensal microbes constituting the skin microbiome. is a…”
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IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge by Kim, Hwan Keun, DeDent, Andrea, Cheng, Alice G, McAdow, Molly, Bagnoli, Fabio, Missiakas, Dominique M, Schneewind, Olaf

“…Abstract Staphylococcus aureus is the most frequent cause of bacteremia and hospital-acquired infection, however a vaccine that prevents staphylococcal disease…”
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Virulence Gene Expression of Staphylococcus aureus in Human Skin by Cruz, Ana Rita, van Strijp, Jos A. G., Bagnoli, Fabio, Manetti, Andrea G. O.

“…Staphylococcus aureus is the main cause of human skin and soft tissue infections. However, S. aureus pathogenicity within the skin is not fully characterized…”
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Deciphering the Pathological Role of Staphylococcal α-Toxin and Panton-Valentine Leukocidin Using a Novel Ex Vivo Human Skin Model by Olaniyi, Reuben Olayinka, Pancotto, Laura, Grimaldi, Luca, Bagnoli, Fabio

“…alpha-toxin and Panton-Valentine leukocidin (PVL) have been reported to play critical roles in different animal models of skin infection. These models,…”
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Staphylococcal Protein A Induces Leukocyte Necrosis by Complexing with Human Immunoglobulins by Fox, Proinnsias G, Schiavetti, Francesca, Rappuoli, Rino, McLoughlin, Rachel M, Bagnoli, Fabio

“…One of the defining features of Staphylococcus aureus is its ability to evade and impair the human immune response through expression of staphylococcal protein…”
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The adherens junctions control susceptibility to Staphylococcus aureus α-toxin by Popov, Lauren M, Marceau, Caleb D, Starkl, Philipp M, Lumb, Jennifer H, Shah, Jimit, Guerrera, Diego, Cooper, Rachel L, Merakou, Christina, Bouley, Donna M, Meng, Wenxiang, Kiyonari, Hiroshi, Takeichi, Masatoshi, Galli, Stephen J, Bagnoli, Fabio, Citi, Sandra, Carette, Jan E, Amieva, Manuel R

“…Staphylococcus aureus is both a transient skin colonizer and a formidable human pathogen, ranking among the leading causes of skin and soft tissue infections…”
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The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine development by Bear, Alex, Locke, Thomas, Rowland-Jones, Sarah, Pecetta, Simone, Bagnoli, Fabio, Darton, Thomas C.

“…While Staphylococcus aureus ( S. aureus ) bacteria are part of the human commensal flora, opportunistic invasion following breach of the epithelial layers can…”
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Vaccination with staphylococcal protein A protects mice against systemic complications of skin infection recurrences by Mandelli, Andrea Paola, Magri, Greta, Tortoli, Marco, Torricelli, Stefania, Laera, Donatello, Bagnoli, Fabio, Finco, Oretta, Bensi, Giuliano, Brazzoli, Michela, Chiarot, Emiliano

“…Skin and soft tissue infections (SSTIs) are the most common diseases caused by ( ), which can progress to threatening conditions due to recurrences and…”
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Reverse development of vaccines against antimicrobial-resistant pathogens by Bagnoli, Fabio, Galgani, Ilaria, Vadivelu, V. Kumaran, Phogat, Sanjay

“…Vaccine R&D is typically a lengthy process taking >10 years. However, vaccines still fail in clinical development because of unreliable animal models or absent…”
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Helicobacter Pylori CagA Induces a Transition from Polarized to Invasive Phenotypes in MDCK Cells by Fabio Bagnoli, Ludovico Buti, Tompkins, Lucy, Covacci, Antonello, Amieva, Manuel R.

“…CagA is a bacterial effector protein of Helicobacter pylori that is translocated via a type IV secretion system into gastric epithelial cells. We previously…”
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One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A by Mancini, Francesca, Monaci, Elisabetta, Lofano, Giuseppe, Torre, Antonina, Bacconi, Marta, Tavarini, Simona, Sammicheli, Chiara, Arcidiacono, Letizia, Galletti, Bruno, Laera, Donatello, Pallaoro, Michele, Tuscano, Giovanna, Fontana, Maria Rita, Bensi, Giuliano, Grandi, Guido, Rossi-Paccani, Silvia, Nuti, Sandra, Rappuoli, Rino, De Gregorio, Ennio, Bagnoli, Fabio, Soldaini, Elisabetta, Bertholet, Sylvie

“…A rapidly acting, single dose vaccine against Staphylococcus aureus would be highly beneficial for patients scheduled for major surgeries or in intensive care…”
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Natural Human Immunity Against Staphylococcal Protein A Relies on Effector Functions Triggered by IgG3 by Boero, Elena, Cruz, Ana Rita, Pansegrau, Werner, Giovani, Cinzia, Rooijakkers, Suzan H M, van Kessel, Kok P M, van Strijp, Jos A G, Bagnoli, Fabio, Manetti, Andrea G O

“…Staphylococcal protein A (SpA) is a multifunctional, highly conserved virulence factor of . By binding the Fc portion of all human IgG subclasses apart from…”
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Human Endogenous Retrovirus K (HML-2) Elements in the Plasma of People with Lymphoma and Breast Cancer by CONTRERAS-GALINDO, Rafael, KAPLAN, Mark H, MARKOVITZ, David M, LEISSNER, Philippe, VERJAT, Thibault, FERLENGHI, Ilaria, BAGNOLI, Fabio, GIUSTI, Fabiola, DOSIK, Michael H, HAYES, Daniel F, GITLIN, Scott D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination by Corrado, Alessia, Donato, Paolo, Maccari, Silvia, Cecchi, Raffaella, Spadafina, Tiziana, Arcidiacono, Letizia, Tavarini, Simona, Sammicheli, Chiara, Laera, Donatello, Manetti, Andrea Guido Oreste, Ruggiero, Paolo, Galletti, Bruno, Nuti, Sandra, De Gregorio, Ennio, Bertholet, Sylvie, Seubert, Anja, Bagnoli, Fabio, Bensi, Giuliano, Chiarot, Emiliano

“…Staphylococcus aureus is the major cause of human septic arthritis and osteomyelitis, which deserve special attention due to their rapid evolution and…”
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A Second Pilus Type in Streptococcus pneumoniae Is Prevalent in Emerging Serotypes and Mediates Adhesion to Host Cells by BAGNOLI, Fabio, MOSCHIONI, Monica, HILLERINGMANN, Markus, PANSEGRAU, Werner, CENSINI, Stefano, RAPPUOLI, Rino, COVACCI, Antonello, MASIGNANI, Vega, BAROCCHI, Michele A, DONATI, Claudio, DIMITROVSKA, Valentina, FERLENGHI, Ilaria, FACCIOTTI, Claudia, MUZZI, Alessandro, GIUSTI, Fabiola, EMOLO, Carla, SINISI, Antonella

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Absence of Protein A Expression Is Associated With Higher Capsule Production in Staphylococcal Isolates by Brignoli, Tarcisio, Manetti, Andrea G O, Rosini, Roberto, Haag, Andreas F, Scarlato, Vincenzo, Bagnoli, Fabio, Delany, Isabel

“…is a major human pathogen, and a leading cause of soft tissue and blood stream infections. One of the causes of its success as a pathogen is the peculiar array…”
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