Search Results - "Fabian, R J"

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase by FABIAN, J. R, DAAR, I. O, MORRISON, D. K

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14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner by Michaud, Neil R., Fabian, John R., Mathes, Karen D., Morrison, Deborah K.

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Requirement for Raf and MAP Kinase Function during the Meiotic Maturation of Xenopus Oocytes by Fabian, John R., Morrison, Deborah K., Daar, Ira O.

“…The role of Raf and MAPK (mitogen-activated protein kinase) during the maturation of Xenopus oocytes was investigated. Treatment of oocytes with progesterone…”
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Expression of the mouse Ren-1 gene in the coagulating gland: localization and regulation by FABIAN, J. R, KANE, C. M, ABEL, K. J, GROSS, K. W

“…The components of the renin-angiotensin system have been detected in various reproductive tissues of mammals including the testis, epididymis, ovary, and…”
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A Single Amino Acid Change in Raf-1 Inhibits Ras Binding and Alters Raf-1 Function by Fabian, John R., Vojtek, Anne B., Cooper, Jonathan A., Morrison, Deborah K.

“…Ras and Raf-1 are key proteins involved in the transmission of developmental and proliferative signals generated by receptor and nonreceptor tyrosine kinases…”
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Allele-specific Expression of the Murine Ren-1 Genes by Fabian, J R, Field, L J, McGowan, R A, Mullins, J J, Sigmund, C D, Gross, K W

“…Inbred strains of mice carry either one of two alleles for the Ren-1 gene on chromosome 1; Ren-1c or Ren-1d. The Ren-1d allele is found in association with a…”
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Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice by Sigmund, C D, Jones, C A, Fabian, J R, Mullins, J J, Gross, K W

“…The tissue specific expression of a fusion transgene consisting of 4.6 kb of Ren-2 5' flanking sequence and the SV40 T antigen viral oncogene was analyzed by…”
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Antibacterial activities, nephrotoxicity, and ototoxicity of a new aminoglycoside, Win 42122-2 by P E Came, J R O'Connor, R A Dobson, R B Wagner, R J Fabian

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Subarachnoid administration of iohexol in cynomolgus monkeys by Drobeck, H P, Mayes, B A, Barbolt, T A, Fabian, R J, Kimball, J P, Slighter, Jr, R R

“…A non-ionic diagnostic medium, iohexol, was administered by subarachnoid injection to groups of six cynomolgus monkeys and compared with the vehicle,…”
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Role of lysosomes in carrageenan-induced cecal ulceration by Abraham, R, Fabian, R J, Golberg, L, Coulston, F

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Carrageenan-induced squamous metaplasia of the rectal mucosa in the rat by Fabian, R J, Abraham, R, Coulston, F, Golberg, L

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Induced corneal opacities in the rat by Fabian, R J, Bond, J M, Drobeck, H P

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Morphologic effects of 3,4',5-tribromosalicylanilide in male rats by Benitz, K F, Iatropoulos, M J, Fabian, R J, Coulston, F

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Glycogen synthase kinase-3 is the predominant insulin-regulated eukaryotic initiation factor 2B kinase in skeletal muscle by Jefferson, Leonard S., Fabian, John R., Kimball, Scot R.

“…Eukaryotic initiation factor eIF2B is a guanine nucleotide exchange protein involved in regulation of translation initiation. Phosphorylation of the ε-subunit…”
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Comparative nephrotoxicity of hydroxygentamicin and other aminoglycosides in rats by Slighter, R G, Montenaro, M J, Fabian, R J, Bhandari, J C, Donikian, M R, Drobeck, H P

“…The nephrotoxicity of hydroxygentamicin and amikacin was examined in young adult Fischer 344 rats. Serum creatinine (SCr) and urea nitrogen (BUN) levels were…”
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Role of Proximal Promoter Elements in Regulation of Renin Gene Transcription by Petrovic, N, Black, T A, Fabian, J R, Kane, C, Jones, C A, Loudon, J A, Abonia, J P, Sigmund, C D, Gross, K W

“…Mouse As4.1 cells, obtained after transgene-targeted oncogenesis to induce neoplasia in renal renin-expressing cells, express high levels of renin mRNA from…”
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Disruption of Cellular Translational Control by a Viral Truncated Eukaryotic Translation Initiation Factor 2α Kinase Homolog by Dever, Thomas E., Sripriya, Rajaraman, McLachlin, Jeanne R., Lu, Jingfang, Fabian, John R., Kimball, Scot R., Miller, Lois K.

“…Phosphorylation of eukaryotic translation initiation factor 2α (eIF2α ) is a common cellular mechanism to limit protein synthesis in stress conditions…”
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Subunit Assembly and Guanine Nucleotide Exchange Activity of Eukaryotic Initiation Factor-2B Expressed in Sf9 Cells by Fabian, J R, Kimball, S R, Heinzinger, N K, Jefferson, L S

“…Eukaryotic initiation factor-2B (eIF-2B) is a guanine nucleotide exchange factor (GEF) that plays a key role in the regulation of protein synthesis. In this…”
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Reconstitution and Purification of Eukaryotic Initiation Factor 2B (eIF2B) Expressed in Sf21 Insect Cells by Fabian, John R., Kimball, Scot R., Jefferson, Leonard S.

“…Eukaryotic initiation factor eIF2B plays a key role in the regulation of protein synthesis through its ability to catalyze the exchange of GDP bound to a…”
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Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2alpha. Role of the alpha- and delta-subunits of eiF2b by Kimball, S R, Fabian, J R, Pavitt, G D, Hinnebusch, A G, Jefferson, L S

“…The guanine nucleotide exchange activity of eIF2B plays a key regulatory role in the translation initiation phase of protein synthesis. The activity is…”
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