Search Results - "Fabian, Laszlo"
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Cocrystals of Fenamic Acids with Nicotinamide
Published in Crystal growth & design (03-08-2011)“…Cocrystal formation between nicotinamide and five fenamic acid derivative drugs (flufenamic acid, niflumic acid, tolfenamic acid, mefenamic acid and…”
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NMR-Enhanced Crystallography Aids Open Metal–Organic Framework Discovery Using Solvent-Free Accelerated Aging
Published in Chemistry of materials (26-05-2020)“…We demonstrate the combined use of NMR-enhanced crystallography and solvent-free synthesis by accelerated aging (AA), for the discovery and structural…”
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3
Directing Crystallization Outcomes of Conformationally Flexible Molecules: Polymorphs, Solvates, and Desolvation Pathways of Fluconazole
Published in Molecular pharmaceutics (07-02-2022)“…Control over polymorphism and solvatomorphism in API assisted by structural information, e.g., molecular conformation or associations via hydrogen bonds, is…”
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Chemoenzymatic Synthesis of Fluorinated Cellodextrins Identifies a New Allomorph for Cellulose‐Like Materials
Published in Chemistry : a European journal (18-01-2021)“…Understanding the fine details of the self‐assembly of building blocks into complex hierarchical structures represents a major challenge en route to the design…”
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5
Self-assembling, supramolecular chemistry and pharmacology of amphotericin B: Poly-aggregates, oligomers and monomers
Published in Journal of controlled release (01-01-2022)“…Antifungal drugs such as amphotericin B (AmB) interact with lipids and phospholipids located on fungal cell membranes to disrupt them and create pores, leading…”
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Mechanistic and Kinetic Insight into Spontaneous Cocrystallization of Isoniazid and Benzoic Acid
Published in Molecular pharmaceutics (03-08-2015)“…Solid-state cocrystallization is of contemporary interest because it offers an easy and efficient way to produce cocrystals, which are recognized as…”
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Nonlinear electric response of the diffuse double layer to an abrupt charge displacement inside a biological membrane
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-08-2022)“…•Abrupt, intramolecular charge displacement inside a biological membrane.•Electric response of the diffuse double layer.•Primary light-induced electric signals…”
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An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
Published in Crystal growth & design (06-08-2014)“…Paroxetine HCl can exist as a nonstoichiometric hydrate (Form II) or as a stoichiometric hemihydrate (Form I); the latter is considered to be the stable form…”
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Identification and Characterization of Stoichiometric and Nonstoichiometric Hydrate Forms of Paroxetine HCl: Reversible Changes in Crystal Dimensions as a Function of Water Absorption
Published in Molecular pharmaceutics (03-12-2012)“…Paroxetine hydrochloride (HCl) is an antidepressant drug, reported to exist in the anhydrous form (form II) and as a stable hemihydrate (form I). In this…”
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10
High-speed integrated optical logic based on the protein bacteriorhodopsin
Published in Biosensors & bioelectronics (15-08-2013)“…The principle of all-optical logical operations utilizing the unique nonlinear optical properties of a protein was demonstrated by a logic gate constructed…”
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One-Pot Mechanosynthesis with Three Levels of Molecular Self-Assembly: Coordination Bonds, Hydrogen Bonds and Host-Guest Inclusion
Published in Chemistry : a European journal (23-11-2009)“…Liquid‐assisted grinding (LAG) was used to combine three levels of molecular self‐assembly into a one‐pot mechanochemical approach for the construction of…”
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12
Protein-based ultrafast photonic switching
Published in Optics express (26-09-2011)“…Several inorganic and organic materials have been suggested for utilization as nonlinear optical material performing light-controlled active functions in…”
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13
Automation Potential of a New, Rapid, Microscopy-Based Method for Screening Drug–Polymer Solubility
Published in ACS omega (26-05-2020)“…For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the…”
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19F NMR Spectroscopy as a Highly Sensitive Method for the Direct Monitoring of Confined Crystallization within Nanoporous Materials
Published in Angewandte Chemie International Edition (25-07-2016)“…The introduction of fluorine into the structure of pharmaceuticals has been an effective strategy for tuning their pharmacodynamic properties, with more than…”
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Hydrogen bonding in organic salt hydrates
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2018)“…Abstract only…”
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Investigation of an Amide-Pseudo Amide Hydrogen Bonding Motif within a Series of Theophylline:Amide Cocrystals
Published in Crystal growth & design (06-01-2016)“…The pharmaceutically active compound theophylline (T) was cocrystallized with the amides formamide (1), acetamide (2), N-methylformamide (3),…”
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Dipole-Induced Polymorphs of trans-2-Hydroxycycloheptanecarboxylic Acid with Virtually the Same Unit Cell
Published in Journal of the American Chemical Society (08-01-2003)“…The polymorphs of trans-2-hydroxycycloheptanecarboxylic acid have exactly the same lattice parameters and thus mimic isomorphism. They differ only in their…”
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18
Crystal Engineering with Alicyclic β-Amino Acids: Construction of Hydrogen-Bonded Bilayers
Published in Crystal growth & design (01-03-2005)“…The crystal structures of four homologous cis-alicyclic β-amino acids present a new recurring layer pattern of hydrogen bonds. This pattern was derived from…”
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Efflux transport of serum amyloid P component at the blood-brain barrier
Published in European journal of microbiology & immunology (01-12-2013)“…Serum amyloid P component (SAP), a member of the innate immune system, does not penetrate the brain in physiological conditions; however, SAP is a stabilizing…”
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20
Mechanism of dehydration in a non-porous variable hydrate
Published in Acta crystallographica. Section A, Foundations and advances (05-08-2014)“…Abstract only Paroxetine hydrochloride form II (PHCl-II) is a variable hydrate with a peculiar behaviour [1]. It changes its water content in response to…”
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