Search Results - "Faber, Matthew S."
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High-Performance Electrocatalysis Using Metallic Cobalt Pyrite (CoS2) Micro- and Nanostructures
Published in Journal of the American Chemical Society (16-07-2014)“…The development of efficient and robust earth-abundant electrocatalysts for the hydrogen evolution reaction (HER) is an ongoing challenge. We report metallic…”
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Earth-Abundant Metal Pyrites (FeS2, CoS2, NiS2, and Their Alloys) for Highly Efficient Hydrogen Evolution and Polysulfide Reduction Electrocatalysis
Published in Journal of physical chemistry. C (18-09-2014)“…Many materials have been explored as potential hydrogen evolution reaction (HER) electrocatalysts to generate clean hydrogen fuel via water electrolysis, but…”
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Earth-Abundant Cobalt Pyrite (CoS2) Thin Film on Glass as a Robust, High-Performance Counter Electrode for Quantum Dot-Sensitized Solar Cells
Published in The journal of physical chemistry letters (06-06-2013)“…We report a cobalt pyrite (cobalt disulfide, CoS2) thin film on glass as a robust, high-performance, low-cost, earth-abundant counter electrode for…”
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Synthesis and Properties of Semiconducting Iron Pyrite (FeS2) Nanowires
Published in Nano letters (11-04-2012)“…We report the growth and structural, electrical, and optical characterization of vertically oriented single-crystalline iron pyrite (FeS2) nanowires…”
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N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function
Published in PloS one (29-01-2013)“…The vasodegenerative phase of diabetic retinopathy is characterized by not only retinal vascular degeneration but also inadequate vascular repair due to…”
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Changes in the daily rhythm of lipid metabolism in the diabetic retina
Published in PloS one (01-04-2014)“…Disruption of circadian regulation was recently shown to cause diabetes and metabolic disease. We have previously demonstrated that retinal lipid metabolism…”
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Deep sequencing methods for protein engineering and design
Published in Current opinion in structural biology (01-08-2017)“…•Deep sequencing permits examination of local protein fitness landscapes.•NGS aids in engineering affinity and specificity for protein molecular…”
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Data-driven engineering of protein therapeutics
Published in Current opinion in biotechnology (01-12-2019)“…[Display omitted] •Low-cost reading and writing of DNA expands protein sequence-function datasets.•Analysis of natural sequences informs mutant selection for…”
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Evaluation of sex-specific gene expression in archived dried blood spots (DBS)
Published in International journal of molecular sciences (01-08-2012)“…Screening newborns for treatable serious conditions is mandated in all US states and many other countries. After screening, Guthrie cards with residual blood…”
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Impact of In Vivo Protein Folding Probability on Local Fitness Landscapes
Published in Molecular biology and evolution (01-12-2019)“…Abstract It is incompletely understood how biophysical properties like protein stability impact molecular evolution and epistasis. Epistasis is defined as…”
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Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing
Published in The Journal of biological chemistry (30-10-2015)“…Knowledge of the fine location of neutralizing and non-neutralizing epitopes on human pathogens affords a better understanding of the structural basis of…”
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User-defined single pot mutagenesis using unamplified oligo pools
Published in Protein engineering, design and selection (10-09-2019)“…Abstract User-defined mutagenic libraries are fundamental for applied protein engineering workflows. Here we show that unamplified oligo pools can be used to…”
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Spontaneous Growth and Phase Transformation of Highly Conductive Nickel Germanide Nanowires
Published in ACS nano (28-06-2011)“…We report the synthesis, phase transformation, and electrical property measurement of single-crystal NiGe and ε-Ni5Ge3 nanowires (NWs). NiGe NWs were…”
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Saturation Mutagenesis Genome Engineering of Infective ΦX174 Bacteriophage via Unamplified Oligo Pools and Golden Gate Assembly
Published in ACS synthetic biology (17-01-2020)“…Here we present a novel protocol for the construction of saturation single-siteand massive multisitemutant libraries of a bacteriophage. We segmented the…”
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1193 Synergistic targeting of multiple activating pathways with natural killer cell engagers
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundTumor microenvironment induced antigens present a unique opportunity to effectively target diseased tissue over normal and to modulate the immune…”
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Abstract 5654: Affinity tuned Xmab®2+1 anti-mesothelin x anti-CD3 bispecific antibody induces selective T cell-dependent cellular cytotoxicity of human ovarian cancer cells
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Mesothelin (MSLN) is a tumor-associated antigen highly expressed in ovarian tumors. Current treatment options for ovarian cancer have only modest efficacy and…”
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Abstract 1860: Bispecific claudin-6 x CD3 antibodies in a 2 + 1 format demonstrate selectivity and activity on human ovarian cancer cells
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…There is a large unmet need for targeted therapies to treat ovarian cancer and other solid tumors. A promising strategy is the use of T cell engaging…”
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Abstract 2983: Tumor-specific CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…T cells in the tumor micro-environment require TCR/MHC engagement and co-stimulatory receptor engagement to achieve optimal activation. Solid tumor cells lack…”
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