Search Results - "Faber, Laura M"

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients by Franssen, Laurens E, Nijhof, Inger S, Couto, Suzana, Levin, Mark-David, Bos, Gerard M J, Broijl, Annemiek, Klein, Saskia K, Ren, Yan, Wang, Maria, Koene, Harry R, Bloem, Andries C, Beeker, Aart, Faber, Laura M, van der Spek, Ellen, Raymakers, Reinier, Leguit, Roos J, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk, Mutis, Tuna, Thakurta, Anjan, Qian, Xiaozhong, van de Donk, Niels W C J

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The Effect of SF3B1 Mutation on the DNA Damage Response and Nonsense-Mediated mRNA Decay in Cancer by Leeksma, Alexander C, Derks, Ingrid A M, Kasem, M Haidar, Kilic, Emine, de Klein, Annelies, Jager, Martine J, van de Loosdrecht, Arjan A, Jansen, Joop H, Navrkalova, Veronika, Faber, Laura M, Zaborsky, Nadja, Egle, Alexander, Zenz, Thorsten, Pospisilova, Sarka, Abdel-Wahab, Omar, Kater, Arnon P, Eldering, Eric

“…Recurrent mutations in splicing factor 3B subunit 1 ( ) have been identified in several malignancies and are associated with an increased expression of 3'…”
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High‐throughput Proteomics Identifies THEMIS2 as Independent Biomarker of Treatment‐free Survival in Untreated CLL by Hengeveld, Paul J., Kolijn, P. Martijn, Demmers, Jeroen A.A., Doff, Wouter, Dubois, Julie M.N., Rijken, Melissa, Assmann, Jorn L.J.C., Straten, Lina, Boiten, Henk Jan, Gussinklo, Kirsten J., Valk, Peter J.M., Faber, Laura M., Westerweel, Peter E., Kater, Arnon P., Levin, Mark‐David, Langerak, Anton W.

“…It remains challenging in chronic lymphocytic leukemia (CLL) to distinguish between patients with favorable and unfavorable time‐to‐first treatment (TTFT)…”
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Safety of Switching From a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients With Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial by Joosten, Linda P T, van Doorn, Sander, van de Ven, Peter M, Köhlen, Bart T G, Nierman, Melchior C, Koek, Huiberdina L, Hemels, Martin E W, Huisman, Menno V, Kruip, Marieke, Faber, Laura M, Wiersma, Nynke M, Buding, Wim F, Fijnheer, Rob, Adriaansen, Henk J, Roes, Kit C, Hoes, Arno W, Rutten, Frans H, Geersing, Geert-Jan

“…There is ambiguity whether frail patients with atrial fibrillation managed with vitamin K antagonists (VKAs) should be switched to a non-vitamin K oral…”
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Chest X-Ray Not Routinely Indicated Prior to the YEARS Algorithm in the Diagnostic Management of Suspected Pulmonary Embolism by van der Pol, Liselotte M., Tromeur, Cecile, Faber, Laura M., van der Hulle, Tom, Kroft, Lucia J. M., Mairuhu, Albert T. A., de Roos, Albert, Huisman, Menno V., Klok, Frederikus A.

“…Abstract Background  The YEARS algorithm was designed to simplify the diagnostic process of suspected pulmonary embolism (PE) and to reduce the number of…”
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Implementation of a clinical decision-making tool for perioperative management of vitamin K antagonists in patients with atrial fibrillation by Hamulyák, Eva N., Westenberg, Dirk, Bresser, Carlinda, Sissing, Simone, Ruiter, Marjan, Scheres, Luuk J.J., Wals, Arian, Faber, Laura M.

“…•Perioperative management of anticoagulant treatment is challenging.•An integrated clinical decision-making tool enables an informed management decision and…”
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Fixed Versus Variable Dosing of Prothrombin Complex Concentrate for Bleeding Complications of Vitamin K Antagonists—The PROPER3 Randomized Clinical Trial by Abdoellakhan, Rahat A., Khorsand, Nakisa, ter Avest, Ewoud, Lameijer, Heleen, Faber, Laura M., Ypma, Paula F., Nieuwenhuizen, Laurens, Veeger, Nic J.G. M., Meijer, Karina

“…To determine if a fixed dose of 1000 IU of 4-factor prothrombin complex concentrate (4F-PCC) is as effective as traditional variable dosing based on body…”
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Improving CLL Vγ9Vδ2-T–cell fitness for cellular therapy by ex vivo activation and ibrutinib by de Weerdt, Iris, Hofland, Tom, Lameris, Roeland, Endstra, Sanne, Jongejan, Aldo, Moerland, Perry D., de Bruin, Renee C.G., Remmerswaal, Ester B.M., ten Berge, Ineke J.M., Liu, Nora, van der Stelt, Mario, Faber, Laura M., Levin, Mark-David, Eldering, Eric, Tonino, Sanne H., de Gruijl, Tanja D., van der Vliet, Hans J., Kater, Arnon P.

“…The efficacy of autologous (αβ) T-cell–based treatment strategies in chronic lymphocytic leukemia (CLL) has been modest. The Vγ9Vδ2-T cell subset consists of…”
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Right Ventricle–to–Left Ventricle Diameter Ratio Measurement Seems to Have No Role in Low-Risk Patients with Pulmonary Embolism Treated at Home Triaged by Hestia Criteria by Hendriks, Stephan V., Klok, Frederikus A., den Exter, Paul L., Eijsvogel, Michiel, Faber, Laura M., Hofstee, Herman M. A., Iglesias del Sol, Antonio, Kroft, Lucia J. M., Mairuhu, Albert T. A., Huisman, Menno V.

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Chronic thromboembolic pulmonary hypertension and clot resolution after COVID-19-associated pulmonary embolism by de Jong, Cindy M M, Visser, Chantal, Bemelmans, Remy H H, Boersma, Wim G, van den Borst, Bram, Burggraaf, J Louise I, Cannegieter, Suzanne C, Ten Cate-Hoek, Arina J, Croles, F Nanne, Faber, Harald J, Faber, Laura M, Hellemons, Merel E, Hessels, Lisa M, Huisman, Menno V, Kamphuisen, Pieter W, Koster, Stephanie C E, Kroft, Lucia J M, van der Lee, Ivo, Leentjens, Jenneke, Meijer, Karina, Ninaber, Maarten K, Sondermeijer, Brigitte M, Stads, Susanne, Vonk Noordegraaf, Anton, Winckers, Kristien, Kruip, Marieke J H A, Klok, Frederikus A

“…The incidence of chronic thromboembolic pulmonary hypertension (CTEPH) in coronavirus disease 2019 (COVID-19) survivors who were diagnosed with acute pulmonary…”
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Outpatient management of cancer-associated pulmonary embolism: A post-hoc analysis from the HOME-PE trial by Chaibi, Sérine, Roy, Pierre-Marie, Guénégou, Armelle Arnoux, Tran, Yohann, Hugli, Olivier, Penaloza, Andréa, Couturaud, Francis, Tromeur, Cécile, Szwebel, Tali-Anne, Pernod, Gilles, Elias, Antoine, Ghuysen, Alexandre, Benhamou, Ygal, Falvo, Nicolas, Juchet, Henry, Nijkeuter, Mathilde, Mairuhu, Ronne, Faber, Laura M., Mahé, Isabelle, Montaclair, Karine, Planquette, Benjamin, Jimenez, David, Huisman, Menno V., Klok, Federikus A., Sanchez, Olivier

“…Cancer-related pulmonary embolism (PE) is associated with poor prognosis. Some decision rules identifying patients eligible for home treatment categorize…”
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Performance of the 4-Level Pulmonary Embolism Clinical Probability Score (4PEPS) in the diagnostic management of pulmonary embolism: An external validation study by Stals, Milou A.M., Beenen, Ludo F.M., Coppens, Michiel, Faber, Laura M., Hofstee, Herman M.A., Hovens, Marcel M.C., Huisman, Menno V., van der Hulle, Tom, Kaasjager, Karin A.H., Kruip, Marieke J.H.A., Mairuhu, Albert T.A., Middeldorp, Saskia, ten Wolde, Marije, Klok, Frederikus A., van Es, Nick

“…BACKGROUNDThe recently published 4-level Pulmonary Embolism Clinical Probability Score (4PEPS) integrates different aspects from currently available diagnostic…”
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Use of the National Early Warning Score for predicting deterioration of patients with acute pulmonary embolism: a post-hoc analysis of the YEARS Study by Bavalia, Roisin, Stals, Milou A M, Mulder, Frits I, Bistervels, Ingrid M, Coppens, Michiel, Faber, Laura M, Hendriks, Stephan V, Hofstee, Herman M A, Huisman, Menno V, van der Hulle, Tom, Mairuhu, Albert T A, Kruip, Marieke J H A, Middeldorp, Saskia, Klok, Frederikus A, Hutten, Barbara A, Holleman, Frits

“…The Pulmonary Embolism Severity Index (PESI) and the simplified PESI (sPESI) are validated scores for mortality prediction in patients with pulmonary embolism…”
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Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma by Nijhof, Inger S., Franssen, Laurens E., Levin, Mark-David, Bos, Gerard M.J., Broijl, Annemiek, Klein, Saskia K., Koene, Harry R., Bloem, Andries C., Beeker, Aart, Faber, Laura M., van der Spek, Ellen, Ypma, Paula F., Raymakers, Reinier, van Spronsen, Dick-Johan, Westerweel, Peter E., Oostvogels, Rimke, van Velzen, Jeroen, van Kessel, Berris, Mutis, Tuna, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M., van de Donk, Niels W.C.J.

“…The prognosis of multiple myeloma (MM) patients who become refractory to lenalidomide and bortezomib is very poor, indicating the need for new therapeutic…”
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A Tool Integrated into the Electronic Health Record to Guide Proper Decision-Making Regarding Peri-Endoscopic Anticoagulant Management: A Retrospective Cohort Study by Plender, Anja, Graumans, Suzanne E, Gielisse, Eric, Bresser-de Ruyter, Carlinda, Sissing, Simone, Ruiter-Jakobs, Marjan C, Wals, Arian, Faber, Laura M

“…-Anticoagulants, such as vitamin-K antagonists (VKA) and direct oral anticoagulants (DOAC), are widely used among patients who undergo endoscopic procedures…”
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Current practice patterns of outpatient management of acute pulmonary embolism: A post-hoc analysis of the YEARS study by Hendriks, Stephan V., Bavalia, Roisin, van Bemmel, Thomas, Bistervels, Ingrid M., Eijsvogel, Michiel, Faber, Laura M., Fogteloo, Jaap, Hofstee, Herman M.A., van der Hulle, Tom, Iglesias del Sol, Antonio, Kruip, Marieke J.H.A., Mairuhu, Albert T.A., Middeldorp, Saskia, Nijkeuter, Mathilde, Huisman, Menno V., Klok, Frederikus A.

“…Studies have shown the safety of home treatment of patients with pulmonary embolism (PE) at low risk of adverse events. Management studies focusing on home…”
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Comparison of two methods for selection of out of hospital treatment in patients with acute pulmonary embolism by Zondag, Wendy, den Exter, Paul L, Crobach, Monique J T, Dolsma, Anneke, Donker, Marjolein L, Eijsvogel, Michiel, Faber, Laura M, Hofstee, Herman M A, Kaasjager, Karin A H, Kruip, Marieke J H A, Labots, Geert, Melissant, Christian F, Sikkens, Michelle S G, Huisman, Menno V

“…The aim of this study is to compare the performance of two clinical decision rules to select patients with acute pulmonary embolism (PE) for outpatient…”
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Uncertain Value of High‐sensitive Troponin T for Selecting Patients With Acute Pulmonary Embolism for Outpatient Treatment by Hestia Criteria by Hendriks, Stephan V., Lankeit, Mareike, Exter, Paul L., Zondag, Wendy, Brouwer, Rolf, Eijsvogel, Michiel, Grootenboers, Marco J., Faber, Laura M., Heller‐Baan, Roxanne, Hofstee, Herman M. A., Iglesias del Sol, Antonio, Mairuhu, Albert T. A., Melissant, Christian F., Peltenburg, Henny G., Ree, Marcel A., Serné, Erik H., Konstantinides, Stavros, Klok, Frederikus A., Huisman, Menno V., Courtney, D. Mark

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Randomised controlled trial protocol to evaluate a fixed dose prothrombin complex concentrate against the variable dose in vitamin K antagonist related bleeding (PROPER3) by Abdoellakhan, Rahat A, Khorsand, Nakisa, Van Hest, Reinier M, Veeger, Nic, Ter Avest, Ewoud, Ypma, Paula F, Faber, Laura M, Meijer, Karina

“…IntroductionThere is currently little evidence for the optimal dosing strategy of four-factor prothrombin complex concentrates (PCC) in vitamin K antagonist…”
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Lenalidomide combined with low-dose cyclophosphamide and prednisone modulates Ikaros and Aiolos in lymphocytes, resulting in immunostimulatory effects in lenalidomide-refractory multiple myeloma patients by Franssen, Laurens E, Nijhof, Inger S, Bjorklund, Chad C, Chiu, Hsiling, Doorn, Ruud, van Velzen, Jeroen, Emmelot, Maarten, van Kessel, Berris, Levin, Mark-David, Bos, Gerard M J, Broijl, Annemiek, Klein, Saskia K, Koene, Harry R, Bloem, Andries C, Beeker, Aart, Faber, Laura M, van der Spek, Ellen, Raymakers, Reinier, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M, Thakurta, Anjan, Qian, Xiaozhong, Mutis, Tuna, van de Donk, Niels W C J

“…We recently showed that the outcome of multiple myeloma (MM) patients treated in the REPEAT study (evaluation of lenalidomide combined with low-dose…”
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