Search Results - "Faber, James"
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Mouse models of Alzheimer’s disease cause rarefaction of pial collaterals and increased severity of ischemic stroke
Published in Angiogenesis (London) (01-05-2019)“…Vascular dysfunction contributes to the progression and severity of Alzheimer’s disease (AD). Patients with AD also sustain larger infarctions after ischemic…”
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Hypoxia induces de novo formation of cerebral collaterals and lessens the severity of ischemic stroke
Published in Journal of cerebral blood flow and metabolism (01-09-2020)“…Pial collaterals provide protection in stroke. Evidence suggests their formation late during gestation (collaterogenesis) is driven by reduced oxygen levels in…”
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Uncertainty About the Condonation of Formally Non-Compliant Wills, and the Rectification of Cross-Signed Mirror Wills: Is an Act-Based Model the Solution?
Published in Potchefstroom electronic law journal (09-03-2022)“…A recent contribution proposed a processual act-based approach to conceptualising wills in South African law. This approach regards a will as the product of a…”
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Endothelial Nitric Oxide Synthase Deficiency Causes Collateral Vessel Rarefaction and Impairs Activation of a Cell Cycle Gene Network During Arteriogenesis
Published in Circulation research (25-06-2010)“…RATIONALE:The collateral circulation is tissue- and life-saving in obstructive arterial disease. Disappointing outcomes in clinical trials aimed at augmenting…”
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Hypoxia induces heart regeneration in adult mice
Published in Nature (London) (12-01-2017)“…A pathway triggered by chronic severe hypoxia boosts regeneration of injured hearts in adult mice. Hypoxia pathway linked to heart regeneration Hesham Sadek…”
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A Brief Etymology of the Collateral Circulation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2014)“…It is well known that the protective capacity of the collateral circulation falls short in many individuals with ischemic disease of the heart, brain, and…”
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De-novo collateral formation following acute myocardial infarction: Dependence on CCR2+ bone marrow cells
Published in Journal of molecular and cellular cardiology (01-10-2015)“…Abstract Wide variation exists in the extent (number and diameter) of native pre-existing collaterals in tissues of different strains of mice, with supportive…”
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Wide genetic variation in the native pial collateral circulation is a major determinant of variation in severity of stroke
Published in Journal of cerebral blood flow and metabolism (01-05-2010)“…Severity of stroke varies widely among individuals. Whether differences in the extent of the native (preexisting) pial collateral circulation exist and…”
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Vascular contributions to cognitive impairment and dementia including Alzheimer's disease
Published in Alzheimer's & dementia (01-06-2015)“…Abstract Scientific evidence continues to demonstrate the linkage of vascular contributions to cognitive impairment and dementia such as Alzheimer's disease…”
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Collateral Vessels Have Unique Endothelial and Smooth Muscle Cell Phenotypes
Published in International journal of molecular sciences (24-07-2019)“…Collaterals are unique blood vessels present in the microcirculation of most tissues that, by cross-connecting a small fraction of the outer branches of…”
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High-altitude rodents have abundant collaterals that protect against tissue injury after cerebral, coronary and peripheral artery occlusion
Published in Journal of cerebral blood flow and metabolism (01-04-2021)“…Collateral number/density varies widely in brain and other tissues among strains of Mus musculus mice due to differences in genetic background. Recent studies…”
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Formation and maturation of the native cerebral collateral circulation
Published in Journal of molecular and cellular cardiology (01-08-2010)“…Abstract The native (pre-existing) collateral circulation minimizes tissue injury if obstructive vascular disease develops. Evidence suggests that large…”
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Aerobic exercise prevents rarefaction of pial collaterals and increased stroke severity that occur with aging
Published in Journal of cerebral blood flow and metabolism (01-11-2017)“…Variation in extent of the brain’s collateral circulation is an important determinant of variation in the severity of stroke and efficacy of revascularization…”
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Aging Causes Collateral Rarefaction and Increased Severity of Ischemic Injury in Multiple Tissues
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2011)“…OBJECTIVE—Aging is a major risk factor for increased ischemic tissue injury. Whether collateral rarefaction and impaired remodeling contribute to this is…”
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Retinal vessel multifractals predict pial collateral status in patients with acute ischemic stroke
Published in PloS one (05-05-2022)“…Pial collateral blood flow is a major determinant of the outcomes of acute ischemic stroke. This study was undertaken to determine whether retinal vessel…”
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Cerebral Collateral Circulation: A Review in the Context of Ischemic Stroke and Mechanical Thrombectomy
Published in World neurosurgery (01-02-2019)“…The pial (leptomenigeal) collateral circulation is a key determinant of functional outcome after mechanical thrombectomy after large-vessel ischemic stroke…”
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Strain-dependent variation in collateral circulatory function in mouse hindlimb
Published in Physiological genomics (01-08-2010)“…The extent (density and diameter) of the native (preexisting) collateral circulation in healthy tissues and the capacity of collaterals to enlarge/remodel in…”
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Vascular Endothelial Growth Factor-A Specifies Formation of Native Collaterals and Regulates Collateral Growth in Ischemia
Published in Circulation research (24-10-2008)“…The density of native (preexisting) collaterals and their capacity to enlarge into large conduit arteries in ischemia (arteriogenesis) are major determinants…”
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Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart
Published in Journal of molecular and cellular cardiology (01-01-2021)“…Collateral vessels lessen myocardial ischemia when acute or chronic coronary obstruction occurs. It has long been assumed that although native (pre-existing)…”
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Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation
Published in PloS one (06-03-2012)“…Native (pre-existing) collaterals are arteriole-to-arteriole anastomoses that interconnect adjacent arterial trees and serve as endogenous bypass vessels that…”
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