Search Results - "Fabbro, Michel"
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Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer
Published in Critical reviews in oncology/hematology (01-02-2014)“…Abstract Ovarian carcinoma is the most lethal gynaecologic malignancy. Despite wide initial sensibility to chemotherapy especially to platinum-based regimens,…”
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Bevacizumab, olaparib, and durvalumab in patients with relapsed ovarian cancer: a phase II clinical trial from the GINECO group
Published in Nature communications (05-03-2024)“…Most patients with advanced ovarian cancer (AOC) ultimately relapse after platinum-based chemotherapy. Combining bevacizumab, olaparib, and durvalumab likely…”
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Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial
Published in The lancet oncology (01-07-2014)“…Summary Background Angiogenesis is a valid target in the treatment of epithelial ovarian cancer. Trebananib inhibits the binding of angiopoietins 1 and 2 to…”
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Primary CNS lymphoma at first relapse/progression: characteristics, management, and outcome of 256 patients from the French LOC network
Published in Neuro-oncology (Charlottesville, Va.) (01-09-2016)“…Treatment of relapsed/refractory (R/R) primary CNS lymphoma (PCNSL) is poorly defined, because randomized trials and large studies are lacking. The aim of this…”
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HE4 and CA-125 kinetics to predict outcome in patients with recurrent epithelial ovarian carcinoma: the META4 clinical trial
Published in Frontiers in oncology (11-01-2024)“…HE4 and CA-125 are used for epithelial ovarian cancer (EOC) screening, diagnosis, and follow-up. Our objective was to study HE4 and CA-125 kinetics in patients…”
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Bevacizumab in recurrent WHO grades II-III glioma
Published in Frontiers in oncology (18-07-2023)“…The management of recurrent WHO grades II-III (rGII-III) glioma is not well established. This study describes the clinical outcomes in patients who received…”
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Differential Sensitivity of Germline and Somatic BRCA Variants to PARP Inhibitor in High-Grade Serous Ovarian Cancer
Published in International journal of molecular sciences (16-09-2023)“…Purpose: The introduction of PARP inhibitors (PARPis) as a treatment option for patients with high-grade serous ovarian cancer (HGSOC) modified the approach of…”
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The CD47/TSP-1 axis: a promising avenue for ovarian cancer treatment and biomarker research
Published in Molecular cancer (14-08-2024)“…Ovarian cancer (OC) remains one of the most challenging and deadly malignancies facing women today. While PARP inhibitors (PARPis) have transformed the…”
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PD1 and PDL1 expression in primary central nervous system diffuse large B‐cell lymphoma are frequent and expression of PD1 predicts poor survival
Published in Hematological oncology (01-12-2017)“…Primary central nervous system diffuse large B‐cell lymphoma (PCNS‐DLBCL) is a rare and aggressive type of diffuse large B‐cell lymphoma (DLBCL) whit poorly…”
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Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer
Published in Breast cancer research : BCR (01-01-2009)“…We evaluated whether CK19, one of the main cytoskeleton proteins of epithelial cells, is released as full-length protein from viable tumor cells and whether…”
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Combination of neoadjuvant chemotherapy followed by surgical resection as a new strategy for WHO grade II gliomas: a study of cognitive status and quality of life
Published in Journal of neuro-oncology (2012)“…Diffuse WHO grade II (GIIG) may be unresectable when involving critical structures. To assess the feasibility and functional tolerance (cognition and quality…”
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PIK3CA Pathway Mutations Predictive of Poor Response Following Standard Radiochemotherapy ± Cetuximab in Cervical Cancer Patients
Published in Clinical cancer research (01-06-2015)“…EGFR is frequently overexpressed in cervical cancer, suggesting EGFR blockade as a promising treatment approach. Cetuximab, an anti EGFR antibody, used…”
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Detection and characterization of putative metastatic precursor cells in cancer patients
Published in Clinical chemistry (Baltimore, Md.) (01-03-2007)“…SCs for the circulating rumor antigens mucin 1 (MUC1) or prostate-specific antigen (PSA) were detected in the majority of patiente with metastatic breast…”
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French Brain Tumor DataBase: 5-Year Histological Results on 25 756 Cases
Published in Brain pathology (Zurich, Switzerland) (01-11-2011)“…This work aimed to prospectively record all primary central nervous system tumor (PCNST) cases in France, for which histological diagnosis is available. The…”
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Ribosome biogenesis‐based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group
Published in Molecular oncology (01-01-2023)“…Resistance of advanced hormone‐dependent endometrial carcinoma to endocrine therapy remains a worldwide clinical issue. We recently reported that the…”
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Neoadjuvant chemotherapy may optimize the extent of resection of World Health Organization grade II gliomas: a case series of 17 patients
Published in Journal of neuro-oncology (01-06-2013)“…The involvement of eloquent brain areas may preclude the total/subtotal surgical resection of diffuse low-grade gliomas (DLGGs). The feasibility and functional…”
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Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study
Published in Cancer reports (01-01-2023)“…Background Acceptability and tolerance of chemotherapy on patients treated for breast cancer remain challenging. Complementary approaches such as hypnosis may…”
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Metastatic Paraplegia and Vital Prognosis: Perspectives and Limitations for Rehabilitation Care. Part 1
Published in Archives of physical medicine and rehabilitation (2011)“…Abstract Fattal C, Fabbro M, Gelis A, Bauchet L. Metastatic paraplegia and vital prognosis: perspectives and limitations for rehabilitation care. Part 1…”
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Investigation of Molecular Features Involved in Clinical Responses and Survival in Advanced Endometrial Carcinoma Treated by Hormone Therapy
Published in Journal of personalized medicine (19-04-2022)“…Hormone therapy (HT) is an effective treatment for metastatic endometrial carcinoma (mEC), with limited toxicity and low cost. We focused on molecular analysis…”
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