Search Results - "Fabbretti, Elsa"
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P2X receptors, sensory neurons and pain
Published in Current medicinal chemistry (01-01-2015)“…Pain represents a very large social and clinical problem since the current treatment provides insufficient pain relief. Plasticity of pain receptors together…”
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Amyloid-β Impairs Dendritic Trafficking of Golgi-Like Organelles in the Early Phase Preceding Neurite Atrophy: Rescue by Mirtazapine
Published in Frontiers in molecular neuroscience (03-06-2021)“…Neurite atrophy with loss of neuronal polarity is a pathological hallmark of Alzheimer’s disease (AD) and other neurological disorders. While there is…”
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Mechanisms Mediating the Enhanced Gene Transcription of P2X3 Receptor by Calcitonin Gene-related Peptide in Trigeminal Sensory Neurons
Published in The Journal of biological chemistry (04-07-2008)“…The molecular mechanisms underlying migraine pain remain unclear and probably require sustained facilitation in pain-sensing P2X3 receptors gated by…”
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The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel
Published in Nature communications (10-04-2018)“…Two subclasses of acid-sensing ion channels (ASIC3) and of ATP-sensitive P2X receptors (P2X3Rs) show a partially overlapping expression in sensory neurons…”
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Comparative toxicity of imidacloprid and its transformation product 6-chloronicotinic acid to non-target aquatic organisms: Microalgae Desmodesmus subspicatus and amphipod Gammarus fossarum
Published in Pesticide biochemistry and physiology (01-11-2012)“…[Display omitted] ► Comparative toxicity of imidacloprid and its product 6-chloronicotinic acid. ► Higher toxicity effects of imidacloprid as commercial…”
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Exocytotic Release of ATP from Cultured Astrocytes
Published in The Journal of biological chemistry (28-09-2007)“…Astrocytes appear to communicate with each other as well as with neurons via ATP. However, the mechanisms of ATP release are controversial. To explore whether…”
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TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine
Published in PloS one (2013)“…Latent changes in trigeminal ganglion structure and function resembling inflammatory conditions may predispose to acute attacks of migraine pain. Here, we…”
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Molecular Mechanisms of Sensitization of Pain-transducing P2X3 Receptors by the Migraine Mediators CGRP and NGF
Published in Molecular neurobiology (01-02-2008)“…Migraine headache originates from the stimulation of nerve terminals of trigeminal ganglion neurons that innervate meninges. Characteristic features of…”
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Regulation of P2X3 receptor structure and function
Published in CNS & neurological disorders drug targets (01-09-2012)“…The strong expression of ATP-gated P2X3 receptors by a subpopulation of sensory neurons indicates the important role of these membrane proteins in nociceptive…”
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Brain Natriuretic Peptide Constitutively Downregulates P2X3 Receptors by Controlling their Phosphorylation State and Membrane Localization
Published in Molecular pain (14-11-2015)“…Background ATP-gated P2X3 receptors are important transducers of nociceptive stimuli and are almost exclusively expressed by sensory ganglion neurons. In mouse…”
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Calcitonin gene-related peptide-mediated enhancement of purinergic neuron/glia communication by the algogenic factor bradykinin in mouse trigeminal ganglia from wild-type and R192Q Cav2.1 Knock-in mice: implications for basic mechanisms of migraine pain
Published in The Journal of neuroscience (09-03-2011)“…Within the trigeminal ganglion, crosstalk between neurons and satellite glial cells (SGCs) contributes to neuronal sensitization and transduction of painful…”
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Author Correction: The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel
Published in Nature communications (17-08-2018)“…The originally published version of this article contained an error in the name of the author Flóra Gölöncsér, which was incorrectly given as Flóra Göröncsér…”
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Familial Hemiplegic Migraine CaV2.1 Channel Mutation R192Q Enhances ATP-gated P2X3 Receptor Activity of Mouse Sensory Ganglion Neurons Mediating Trigeminal Pain
Published in Molecular pain (24-08-2010)“…Background: The R192Q mutation of the CACNA1A gene, encoding for the α1 subunit of voltage-gated P/Q Ca2+ channels (Cav2.1), is associated with familial…”
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The C-terminal Src Inhibitory Kinase (Csk)-mediated Tyrosine Phosphorylation Is a Novel Molecular Mechanism to Limit P2X3 Receptor Function in Mouse Sensory Neurons
Published in The Journal of biological chemistry (07-08-2009)“…On sensory neurons, sensitization of P2X3 receptors gated by extracellular ATP contributes to chronic pain. We explored the possibility that receptor…”
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P2X3 receptors are transducers of sensory signals
Published in Brain research bulletin (01-09-2019)“…•ATP-gated P2X3 receptors expressed by sensory neurons transduce pain signals.•P2X3 receptors are modulated by neuropeptides such as CGRP, NGF and…”
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Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine
Published in BMC neuroscience (21-11-2012)“…Enhanced activity of trigeminal ganglion neurons is thought to underlie neuronal sensitization facilitating the onset of chronic pain attacks, including…”
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Lipid Rafts Control P2X3 Receptor Distribution and Function in Trigeminal Sensory Neurons of a Transgenic Migraine Mouse Model
Published in Molecular pain (29-09-2011)“…Background: A genetic knock-in mouse model expressing the R192Q mutation of the α1-subunit of the CaV2.1 channels frequently found in patients with familial…”
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Activation and desensitization of neuronal nicotinic receptors modulate glutamatergic transmission on neonatal rat hypoglossal motoneurons
Published in The European journal of neuroscience (01-12-2005)“…In the neonate the muscles of the tongue, which are exclusively innervated by the XII cranial nerves originating from the brainstem nucleus hypoglossus, must…”
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Molecular biology and electrophysiology of neuronal nicotinic receptors of rat chromaffin cells
Published in The European journal of neuroscience (01-06-2003)“…Neuronal nicotinic acetylcholine receptors of chromaffin cells in the adrenal medulla are physiologically activated by acetylcholine to mediate catecholamine…”
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Rotavirus NSP5: Mapping Phosphorylation Sites and Kinase Activation and Viroplasm Localization Domains
Published in Journal of Virology (01-04-2002)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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