Search Results - "FUSETTI, Fabrizia"

Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface by Bos, Jeffrey, Fusetti, Fabrizia, Driessen, Arnold J. M., Roelfes, Gerard

“…A game of two halves: Artificial metalloenzymes are generated by forming a novel active site on the dimer interface of the transcription factor LmrR. Two…”
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A Proteomics and Transcriptomics Approach to Identify Leukemic Stem Cell (LSC) Markers by Bonardi, Francesco, Fusetti, Fabrizia, Deelen, Patrick, van Gosliga, Djoke, Vellenga, Edo, Schuringa, Jan Jacob

“…Interactions between hematopoietic stem cells and their niche are mediated by proteins within the plasma membrane (PM) and changes in these interactions might…”
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Light-harvesting complex II (LHCII) and its supramolecular organization in Chlamydomonas reinhardtii by Drop, Bartlomiej, Webber-Birungi, Mariam, Yadav, Sathish K.N., Filipowicz-Szymanska, Alicja, Fusetti, Fabrizia, Boekema, Egbert J., Croce, Roberta

“…LHCII is the most abundant membrane protein on earth. It participates in the first steps of photosynthesis by harvesting sunlight and transferring excitation…”
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Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis by van den Boom, Vincent, Maat, Henny, Geugien, Marjan, Rodríguez López, Aida, Sotoca, Ana M., Jaques, Jennifer, Brouwers-Vos, Annet Z., Fusetti, Fabrizia, Groen, Richard W.J., Yuan, Huipin, Martens, Anton C.M., Stunnenberg, Hendrik G., Vellenga, Edo, Martens, Joost H.A., Schuringa, Jan Jacob

“…Polycomb proteins are classical regulators of stem cell self-renewal and cell lineage commitment and are frequently deregulated in cancer. Here, we find that…”
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A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function by Zaini, Mohamad A., Müller, Christine, de Jong, Tristan V., Ackermann, Tobias, Hartleben, Götz, Kortman, Gertrud, Gührs, Karl-Heinz, Fusetti, Fabrizia, Krämer, Oliver H., Guryev, Victor, Calkhoven, Cornelis F.

“…Cellular metabolism is a tightly controlled process in which the cell adapts fluxes through metabolic pathways in response to changes in nutrient supply. Among…”
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Lactococcus lactis YfiA is necessary and sufficient for ribosome dimerization by Puri, Pranav, Eckhardt, Thomas H., Franken, Linda E., Fusetti, Fabrizia, Stuart, Marc C. A., Boekema, Egbert J., Kuipers, Oscar P., Kok, Jan, Poolman, Bert

“…Summary Dimerization and inactivation of ribosomes in Escherichia coli is a two‐step process that involves the binding of ribosome modulation factor (RMF) and…”
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Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells by van den Boom, Vincent, Rozenveld-Geugien, Marjan, Bonardi, Francesco, Malanga, Donatella, van Gosliga, Djoke, Heijink, Anne Margriet, Viglietto, Giuseppe, Morrone, Giovanni, Fusetti, Fabrizia, Vellenga, Edo, Schuringa, Jan Jacob

“…The Polycomb group (PcG) protein BMI1 is a key factor in regulating hematopoietic stem cell (HSC) and leukemic stem cell self-renewal and functions in the…”
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Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab by Schokker, Sandor, Fusetti, Fabrizia, Bonardi, Francesco, Molenaar, Remco J, Mathôt, Ron A A, van Laarhoven, Hanneke W M

“…Given the increasing use of combination therapy with multiple monoclonal antibodies (mAbs), there is a clinical need for multiplexing assays. For the…”
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Proteolysin, a Novel Highly Thermostable and Cosolvent-Compatible Protease from the Thermophilic Bacterium Coprothermobacter proteolyticus by TOPLAK, Ana, BIAN WU, FUSETTI, Fabrizia, QUAEDFLIEG, Peter J. L. M, JANSSEN, Dick B

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Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis by Kataria, Rama, Xu, Xuehua, Fusetti, Fabrizia, Keizer-Gunnink, Ineke, Jin, Tian, van Haastert, Peter J. M., Kortholt, Arjan

“…Heterotrimeric G proteins couple external signals to the activation of intracellular signal transduction pathways. Agonist-stimulated guanine nucleotide…”
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Susceptibility to COPD: differential proteomic profiling after acute smoking by Franciosi, Lorenza, Postma, Dirkje S, van den Berge, Maarten, Govorukhina, Natalia, Horvatovich, Peter L, Fusetti, Fabrizia, Poolman, Bert, Lodewijk, Monique E, Timens, Wim, Bischoff, Rainer, ten Hacken, Nick H T

“…Cigarette smoking is the main risk factor for COPD (Chronic Obstructive Pulmonary Disease), yet only a subset of smokers develops COPD. Family members of…”
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Impact of Lactobacillus plantarum Sortase on Target Protein Sorting, Gastrointestinal Persistence, and Host Immune Response Modulation by Remus, Daniela M, Bongers, Roger S, Meijerink, Marjolein, Fusetti, Fabrizia, Poolman, Bert, de Vos, Paul, Wells, Jerry M, Kleerebezem, Michiel, Bron, Peter A

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Crystal Structure and Carbohydrate-binding Properties of the Human Cartilage Glycoprotein-39 by Fusetti, Fabrizia, Pijning, Tjaard, Kalk, Kor H., Bos, Ebo, Dijkstra, Bauke W.

“…The human cartilage glycoprotein-39 (HCgp-39 or YKL40) is expressed by synovial cells and macrophages during inflammation. Its precise physiological role is…”
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The structural basis for peptide selection by the transport receptor OppA by Berntsson, Ronnie P-A, Doeven, Mark K, Fusetti, Fabrizia, Duurkens, Ria H, Sengupta, Durba, Marrink, Siewert-Jan, Thunnissen, Andy-Mark W H, Poolman, Bert, Slotboom, Dirk-Jan

“…Oligopeptide‐binding protein A (OppA) from Lactococcus lactis binds peptides of an exceptionally wide range of lengths (4–35 residues), with no apparent…”
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Bacillus subtilis SpoIIIJ and YqjG Function in Membrane Protein Biogenesis by SALLER, Manfred J, FUSETTI, Fabrizia, DRIESSEN, Arnold J. M

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The response of Lactococcus lactis to membrane protein production by Marreddy, Ravi K R, Pinto, Joao P C, Wolters, Justina C, Geertsma, Eric R, Fusetti, Fabrizia, Permentier, Hjalmar P, Kuipers, Oscar P, Kok, Jan, Poolman, Bert

“…The biogenesis of membrane proteins is more complex than that of water-soluble proteins, and recombinant expression of membrane proteins in functional form and…”
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Regulation of ykrL (htpX) by Rok and YkrK, a Novel Type of Regulator in Bacillus subtilis by MARCINIAK, Bogumiła C, TRIP, Hein, FUSETTI, Fabrizia, KUIPERS, Oscar P

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Crystal Structure of the Copper-Containing Quercetin 2,3-Dioxygenase from Aspergillus japonicus by Fusetti, Fabrizia, Schröter, Klaus H, Steiner, Roberto A, van Noort, Paula I, Pijning, Tjaard, Rozeboom, Henriëtte J, Kalk, Kor H, Egmond, Maarten R, Dijkstra, Bauke W

“…Quercetin 2,3-dioxygenase is a copper-containing enzyme that catalyzes the insertion of molecular oxygen into polyphenolic flavonols. Dioxygenation catalyzed…”
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Undifferentiated Embryonic Cell Transcription Factor 1 Regulates ESC Chromatin Organization and Gene Expression by Kooistra, Susanne M., van den Boom, Vincent, Thummer, Rajkumar P., Johannes, Frank, Wardenaar, René, Tesson, Bruno M., Veenhoff, Liesbeth M., Fusetti, Fabrizia, O'Neill, Laura P., Turner, Bryan M., de Haan, Gerald, Eggen, Bart J. L.

“…Previous reports showed that embryonic stem (ES) cells contain hyperdynamic and globally transcribed chromatin—properties that are important for ES cell…”
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Selenomethionine incorporation in proteins expressed in Lactococcus lactis by Berntsson, Ronnie P.‐A., Alia Oktaviani, Nur, Fusetti, Fabrizia, Thunnissen, Andy‐Mark W. H., Poolman, Bert, Slotboom, Dirk‐Jan

“…Lactococcus lactis is a promising host for (membrane) protein overproduction. Here, we describe a protocol for incorporation of selenomethionine (SeMet) into…”
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