Search Results - "FUSELIER, Joseph A"

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  1. 1

    Inhibition of Streptococcus mutans biofilms with bacterial-derived outer membrane vesicles by Wang, Yihui, Hoffmann, Joseph P, Baker, Sarah M, Bentrup, Kerstin Höner Zu, Wimley, William C, Fuselier, Joseph A, Bitoun, Jacob P, Morici, Lisa A

    Published in BMC microbiology (24-08-2021)
    “…Biofilms are microbial communities surrounded by a self-produced extracellular matrix which protects them from environmental stress. Bacteria within biofilms…”
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  2. 2

    Burkholderia thailandensis outer membrane vesicles exert antimicrobial activity against drug-resistant and competitor microbial species by Wang, Yihui, Hoffmann, Joseph P., Chou, Chau-Wen, Höner zu Bentrup, Kerstin, Fuselier, Joseph A., Bitoun, Jacob P., Wimley, William C., Morici, Lisa A.

    Published in The journal of microbiology (01-07-2020)
    “…Gram-negative bacteria secrete outer membrane vesicles (OMVs) that play critical roles in intraspecies, interspecies, and bacteria-environment interactions…”
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  3. 3

    Valproic acid induces NET cell growth arrest and enhances tumor suppression of the receptor-targeted peptide-drug conjugate via activating somatostatin receptor type II by Sun, Lichun, Qian, Qingqing, Sun, Guangchun, Mackey, L. Vienna, Fuselier, Joseph A., Coy, David H., Yu, Cui-Yun

    Published in Journal of drug targeting (07-02-2016)
    “…Background: Human pancreatic carcinoids, a type of neuroendocrine tumors, are asymptomatic and difficult to diagnose, with the effects of traditional…”
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    Biological evaluation of 9-thioansamitocin P3 by Vasilevich, Natalya I., Jiang, Huangyu, Xiao, Haihua, Feng, Kunxian, Jian, Chengfang, Chen, Changfeng, Li, Min, Chen, Zhenhua, Pang, Li, Li, Xiang, Chestkov, Alexander V., Sun, Andre H., Xu, Wang, Fuselier, Joseph A., Coy, David H., Sun, Lichun

    “…Highly cytotoxic maytansine derivatives are widely used in targeted tumor delivery. Structure-activity studies published earlier suggested the C9 carbinol to…”
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  6. 6

    Targeted Chemotherapy Using a Cytotoxic Somatostatin Conjugate to Inhibit Tumor Growth and Metastasis in Nude Mice by Sun, Li-Chun, Mackey, L. Vienna, Luo, Jing, Fuselier, Joseph A., Coy, David H.

    Published in Clinical Medicine Insights. Oncology (01-01-2008)
    “…Li-Chun Sun, L. Vienna Mackey, Jing Luo, Joseph A. Fuselier and David H. Coy Department of Medicine, Peptide Research Laboratories, Tulane Health Sciences…”
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  7. 7

    Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n- myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors by Sun, Lichun, Fuselier, Joseph A, Murphy, William A, Coy, David H

    Published in Peptides (New York, N.Y. : 1980) (01-09-2002)
    “…Peptide nucleic acid (PNA) sequences are synthetic versions of naturally ocurring oligonucleotides which display improved binding properties to DNA and RNA,…”
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  8. 8

    Abilities of 3,4-Diarylfuran-2-one Analogs of Combretastatin A-4 to Inhibit Both Proliferation of Tumor Cell Lines and Growth of Relevant Tumors in Nude Mice by LICHUN SUN, VASILEVICH, Natalya I, FUSELIER, Joseph A, COY, David H

    Published in Anticancer research (01-01-2004)
    “…Background: Combretastatin A-4 (CA-4) and its analogs are potent inhibitors of tubulin polymerization and display strong inhibitory activity on both solid…”
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    A conjugate of camptothecin and a somatostatin analog against prostate cancer cell invasion via a possible signaling pathway involving PI3K/Akt, αVβ3/αVβ5 and MMP-2/-9 by Sun, Li-Chun, Luo, Jing, Mackey, L. Vienna, Fuselier, Joseph A, Coy, David H

    Published in Cancer letters (08-02-2007)
    “…Abstract Camptothecin (CPT) was conjugated to the N-terminal of a somatostatin analog (SSA) directly via a carbamate group and a basic N-terminal linking…”
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    Novel Tandem Aldol Intramolecular Cyclization of Substituted N-Benzylpiperidine-4-one: Synthesis of Novel-Type Nitrogen 2,8-Phenanthroline Heterocycles by Kostochka, Michael L., Zajicek, Jaroslav, Fuselier, Joseph A., Etienne, Marcus A., Sun, Lichun, Coy, David H.

    Published in Journal of heterocyclic chemistry (01-11-2015)
    “…A new sub‐type of the intramolecular aldol cyclization reaction has been discovered and characterized. It was used to synthesize novel family of tricyclic,…”
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  13. 13

    Synthesis of camptothecin–amino acid carbamate linkers by Etienne, Marcus A., Kostochka, Mikhail, Fuselier, Joseph A., Coy, David H.

    Published in Amino acids (01-05-2012)
    “…A more convenient and facile approach for the synthesis and production of camptothecin–amino acids carbamate linkers, that can be used in the synthesis of…”
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  14. 14

    Examination of the 1,4-disubstituted azetidinone ring system as a template for combretastatin A-4 conformationally restricted analogue design by SUN, Lichun, VASILEVICH, Natalya I, FUSELIER, Joseph A, HOCART, Simon J, COY, David H

    Published in Bioorganic & medicinal chemistry letters (03-05-2004)
    “…A series of novel 1,4-diaryl-2-azetidinones was prepared by stereospecific Staudinger reaction as conformationally restricted analogues of combretastatin A-4…”
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  15. 15

    Vasoactive intestinal peptide–camptothecin conjugates inhibit the proliferation of breast cancer cells by Moody, Terry W., Mantey, Samuel A., Fuselier, Joseph A., Coy, David H., Jensen, Robert T.

    Published in Peptides (New York, N.Y. : 1980) (01-09-2007)
    “…The effects of vasoactive intestinal peptide–camptothecin (VIP–CPT) conjugates were investigated on breast cancer cells and cells transfected with VIP…”
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  16. 16

    Effects of camptothecin on tumor cell proliferation and angiogenesis when coupled to a bombesin analog used as a targeted delivery vector by Sun, Li-Chun, Luo, Jing, Mackey, Vienna L, Fuselier, Joseph A, Coy, David H

    Published in Anti-cancer drugs (01-03-2007)
    “…The camptothecin-bombesin conjugate termed DC-51-43, as a novel targeted drug delivery system, was examined in over 10 human tumor cell lines and shows a…”
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  17. 17

    Application of human pancreatic carcinoid BON cells for receptor-targeted drug development by Sun, Lichun, Morris, Lynsie M., Luo, Jing, Mackey, L. Vienna, Leslie, Juliana S., Franko-Tobin, Laura G., Fuselier, Joseph A., LePage, Keith T., Coy, David H.

    Published in Journal of drug targeting (01-09-2011)
    “…In our previous study, we found that several tumor cell lines displayed high receptor-specific binding affinity, one of which, the human pancreatic carcinoid…”
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  18. 18

    Study of inhibitory effects of an antiangiogenic somatostatin-camptothecin conjugate on laser-induced choroidal neovascularization in rats by Bezerra, Yanno, Fuselier, Joseph A, Peyman, Gholam A, Oner, Hakan, Drouant, George, Coy, David H

    Published in Retina (Philadelphia, Pa.) (01-04-2005)
    “…To evaluate the ocular toxicity and efficacy of intravitreal camptothecin-somatostatin conjugate (JF-10-81), a somatostatin type 2 receptor-directed,…”
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    An adjustable release rate linking strategy for cytotoxin–Peptide conjugates by Fuselier, Joseph A., Sun, Lichun, Woltering, S.Nathaniel, Murphy, William A., Vasilevich, Natalya, Coy, David H.

    Published in Bioorganic & medicinal chemistry letters (10-03-2003)
    “…Peptide hormones are often rapidly internalized after binding to and activation of their receptors which are sometimes over-expressed on tumor cells. Thus,…”
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  20. 20

    Effects of camptothecin conjugated to a somatostatin analog vector on growth of tumor cell lines in culture and related tumors in rodents by Sun, Lichun, Fuselier, Joseph A, Coy, David H

    Published in Drug delivery (01-01-2004)
    “…Two CPT-SSA conjugates, JF-10-71 and JF-10-81, containing a chemically adjustable release-rate carbamate linker, have been reported previously by us to…”
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