Search Results - "FURUTA, Shigeru"

Perspectives on non-clinical safety evaluation of drug metabolites through the JSOT workshop by Minagawa, Toshiya, Nakano, Kenji, Furuta, Shigeru, Iwasa, Takashi, Takekawa, Koji, Minato, Kouichi, Koga, Toshihisa, Sato, Takashi, Kawashima, Kosuke, Kurahashi, Yoshikazu, Onodera, Hiroshi, Naito, Shinsaku, Nakamura, Kazuichi

“…The prompt and appropriate safety assessment of drug metabolite(s) was mentioned in regulatory guidances such as an International Conference on Harmonisation…”
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Polaprezinc, a zinc compound, is distributed to the lingual epithelium and increases its zinc concentration in zinc-deficient rats by Hamano, Hiroki, Yoshinaga, Koji, Tanaka, Takao, Eta, Runa, Horii, Takayuki, Kawabata, Yoshihiro, Furuta, Shigeru, Takei, Mineo

“…To clarify the mechanism underlying the effect of polaprezinc on hypogeusia, we investigated the uptake of polaprezinc by the tongue in rats. Rats were fed a…”
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Pharmacokinetics and safety of single and multiple doses of Asacol tablets in Japanese healthy volunteers by Ito, Hiroaki, Furuta, Shigeru, Sasaki, Hidetaka, Yoshida, Toyomitsu, Takano, Yuichi, Hibi, Toshifumi

“…Introduction The pharmacokinetics and safety of Asacol ® (Tillotts Pharma AG, Ziefen, Switzerland), which has been used worldwide to treat ulcerative colitis…”
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CURRENT OPINION: SAFETY EVALUATION OF DRUG METABOLITES IN DEVELOPMENT OF PHARMACEUTICALS by NAITO, Shinsaku, FURUTA, Shigeru, YOSHIDA, Takemi, KITADA, Mitsukazu, FUEKI, Osamu, UNNO, Takashi, OHNO, Yasuo, ONODERA, Hiroshi, KAWAMURA, Nobuyuki, KUROKAWA, Misao, SAGAMI, Fumio, SHINODA, Kazutoshi, NAKAZAWA, Takahiro, YAMAZAKI, Tsuneyoshi

“…Safety assessment of drug metabolites in the development of pharmaceuticals was discussed in January 2007 at the kick-off meeting of a "Drug Evaluation Forum",…”
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Suitability of the odor stick identification test for the Japanese in patients suffering from olfactory disturbance by Kobayashi, Masayoshi, Nishida, Kohei, Nakamura, Satoshi, Oishi, Maaya, Shiozaki, Takaya, Majima, Yuichi, Maeda, Taro, Furuta, Shigeru, Takashima, Yasuhiro, Saito, Sachiko

“…We studied the suitability of the Odor Stick Identification Test for the Japanese (OSIT-J) in patients suffering from olfactory disturbance. In 120 patients…”
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Carrier-Mediated Active Transport of a Novel Thromboxane A2 Receptor Antagonist [2-(4-Chlorophenylsulfonylaminomethyl)indan-5-yl]acetate (Z-335) into Rat Liver by KAWABATA, Yoshihiro, FURUTA, Shigeru, SHINOZAKI, Yutaka, KURIMOTO, Tadashi, NISHIGAKI, Ryuichiro

“…To elucidate the transport system by which [2-(4-chlorophenylsulfonylaminomethyl)indan-5-yl]acetate (Z-335) is taken up into the liver, we investigated the…”
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Calcium movement in ischemia-tolerant hippocampal CA1 neurons after transient forebrain ischemia in gerbils by Ohta, S, Furuta, S, Matsubara, I, Kohno, K, Kumon, Y, Sakaki, S

“…Hippocampal CA1 neurons exposed to a nonlethal period (2 min) of ischemia, acquired tolerance to a subsequent lethal 5-min period of ischemia, which usually…”
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The role of early Ca2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils by Nakamura, K, Hatakeyama, T, Furuta, S, Sakaki, S

“…To examine the role of calcium influx in the early phase after brief forebrain ischemia and subsequent delayed neuronal cell death in the hippocampus, 45Ca…”
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Pituitary Metastasis from Carcinoma of the Urinary Bladder Mimicking Pituitary Apoplexy —Case Report by FURUTA, Shigeru, HATAKEYAMA, Takao, ZENKE, Kiichiro, FUKUMOTO, Shinya

“…A 70-year-old male presented with pituitary metastasis from transitional cell carcinoma of the urinary bladder manifesting as sudden headache, transient…”
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Huge Facial Schwannoma Extending Into the Middle Cranial Fossa and Cerebellopontine Angle Without Facial Nerve Palsy: Case Report by FURUTA, Shigeru, HATAKEYAMA, Takao, ZENKE, Kiichiro, NAGATO, Shigeyuki

“…A 46-year-old male presented with a huge facial schwannoma extending into both the middle cranial fossa and the cerebellopontine angle but without manifesting…”
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Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride by Matsunaga, Yugo, Tanaka, Takao, Yoshinaga, Koji, Ueki, Shigeru, Hori, Yuko, Eta, Runa, Kawabata, Yoshihiro, Yoshii, Kazuyoshi, Yoshida, Kenji, Matsumura, Toshihiro, Furuta, Shigeru, Takei, Mineo, Tack, Jan, Itoh, Zen

“…Acotiamide hydrochloride (acotiamide; N-[2-[bis(1-methylethyl) amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl) amino] thiazole-4-carboxamide monohydrochloride…”
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Clinical evaluation of taste dysfunction using a salt-impregnated taste strip by Nishimoto, K, Hirota, R, Egawa, M, Furuta, S

“…We have used special tests to investigate taste function in detail. To evaluate acuity for a salty taste, we used a paper with salt crystals, Salsave. The…”
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Usefulness of Neuroendoscopy in Treating Supracollicular Arachnoid Cysts —Case Report by FURUTA, Shigeru, HATAKEYAMA, Takao, NISHIZAKI, Osamu, FUKUMOTO, Shinya

“…A 12-year-old girl presented with a supracollicular arachnoid cyst manifesting as a compressive headache. Neurological examination on admission revealed no…”
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Synovial sarcoma in the parapharyngeal space: case report and review of the literature by Hanada, Takehiro, Iwashita, Mutsuro, Matsuzaki, Tsutomu, Hanamure, Yutaka, Fukuda, Katsunori, Furuta, Shigeru

“…We encountered a rare case of synovial sarcoma in the parapharynx of a 47-year-old Japanese man. This patient presented with an enlarging tumor in the right…”
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Bacterial examination of sinusitis using antral puncture and irrigation by Adachi, Mitsuo, Furuta, Shigeru, Suzuki, Shinya, Maeda, Tarou

“…Aerobic bacterial examination for sinusitis was conducted using specimens from maxillary sinuses collected by antral puncture in 540 patients--284 men and 256…”
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Retinoblastoma Protein Expression and Prognosis in Laryngeal Cancer by Fumiko Dokiya, Kazuyoshi Ueno, Shuran Ma, Yoshito Eizuru, Shigeru Furuta, Masaru Ohyama

“…Expression of retinoblastoma (Rb) protein was immunohistochemically examined in laryngeal squamous cell neoplasias from 72 patients. Staining patterns were…”
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Chondrosarcoma of the hyoid bone by Itoh, K, Nobori, T, Fukuda, K, Furuta, S, Ohyama, M

“…Chondrosarcoma of the head and neck is relatively rare. We report the sixth case known to us in which the chondrosarcoma had originated in the hyoid bone. The…”
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Relationship between Abnormal Sensation in the Throat and Menopause by Furuta, Shigeru, Nishimoto, Kengo, Deguchi, Koji, Ohyama, Masaru

“…Abnormal sensations in the throat (AST) are commonly encountered in general and otolaryngological practice, especially among middle aged women. These sensation…”
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High-performance liquid chromatographic determination of cimetidine in rat plasma, urine and bile by Kaneniwa, N, Funaki, T, Furuta, S, Watari, N

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Effect of growth temperature on InGaAsP/GaAsP epitaxial growth by FUJII, S, TOBITA, M, FURUTA, S, SAKAI, S, UMENO, M

“…The epitaxial growth condition of InGaAsP on GaAs 0.61 P 0.39 is discussed in conjunction with a lattice latching effect which is shown to have a relationship…”
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