Search Results - "FURMAN, Wayne L"
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1
“Trying to Be a Good Parent” As Defined By Interviews With Parents Who Made Phase I, Terminal Care, and Resuscitation Decisions for Their Children
Published in Journal of clinical oncology (10-12-2009)“…When a child's cancer progresses beyond current treatment capability, the parents are likely to participate in noncurative treatment decision making. One…”
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2
Alveolar soft part sarcoma in children and young adults: A report of 69 cases
Published in Pediatric blood & cancer (01-05-2018)“…Background Alveolar soft part sarcoma (ASPS) is a rare mesenchymal tumor characterized by ASPL‐TFE3 translocation. Apart from complete surgical resection,…”
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3
Upfront window vincristine/irinotecan treatment of high‐risk hepatoblastoma: A report from the Children's Oncology Group AHEP0731 study committee
Published in Cancer (15-06-2017)“…BACKGROUND The identification of new therapies for high‐risk (HR) hepatoblastoma is challenging. Children's Oncology Group study AHEP0731 included a HR stratum…”
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4
A mutational comparison of adult and adolescent and young adult (AYA) colon cancer
Published in Cancer (01-03-2018)“…BACKGROUND It is possible that the relative lack of progress in treatment outcomes among adolescent and young adult (AYA) patients with cancer is caused by a…”
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5
Treatment Outcomes in Black and White Children With Cancer: Results From the SEER Database and St Jude Children's Research Hospital, 1992 Through 2007
Published in Journal of clinical oncology (01-06-2012)“…Treatment outcome for black patients with cancer has been significantly worse than for their white counterparts. We determined whether recent improved…”
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6
End-of-Life Care Preferences of Pediatric Patients With Cancer
Published in Journal of clinical oncology (20-12-2005)“…The viewpoint of the terminally ill child at the time of an end-of-life decision has not been formally investigated. We identified the preferences of children…”
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7
Decision Making by Parents of Children With Incurable Cancer Who Opt for Enrollment on a Phase I Trial Compared With Choosing a Do Not Resuscitate/Terminal Care Option
Published in Journal of clinical oncology (10-07-2010)“…Parents of children with incurable cancer make complex and difficult decisions about remaining treatment options. We compared the self-reported rationale, good…”
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8
Phase I Study of Everolimus in Pediatric Patients With Refractory Solid Tumors
Published in Journal of clinical oncology (20-10-2007)“…To determine the maximum-tolerated dose (MTD), dose-limiting toxicities (DLTs), and pharmacokinetic and pharmacodynamic properties of the mammalian target of…”
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9
Colorectal Carcinoma in Childhood and Adolescence: A Clinicopathologic Review
Published in Journal of clinical oncology (20-12-2007)“…Pediatric colorectal carcinoma (CRC) is rare, but the available data suggest that it is more likely than adult CRC to be advanced at presentation and to have a…”
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10
A Phase 1 and pharmacokinetic study evaluating daily or weekly schedules of the humanized anti-GD2 antibody hu14.18K322A in recurrent/refractory solid tumors
Published in mAbs (01-01-2020)“…Hu14.18K322A is a humanized anti-GD2 monoclonal antibody with a single point mutation that reduces complement-mediated cytotoxicity, with a maximum tolerated…”
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11
Rapid decrease of serum alpha-fetoprotein and tumor volume predicts outcome in children with hepatoblastoma treated with neoadjuvant chemotherapy
Published in International journal of clinical oncology (01-10-2018)“…Background Neoadjuvant chemotherapy is given to children with unresectable hepatoblastoma to increase the rate and safety of curative complete surgical…”
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12
Intensity modulated radiation therapy provides excellent local control in high-risk abdominal neuroblastoma
Published in Pediatric blood & cancer (01-05-2013)“…Background Locoregional failure is a significant concern in patients with high‐risk abdominal neuroblastoma (NB) receiving radiotherapy. Locoregional control…”
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13
Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial
Published in Journal for immunotherapy of cancer (01-03-2020)“…BackgroundNatural killer (NK) cells are one of the main effector populations of immunotherapy with monoclonal antibody and cytokines, used in combination with…”
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14
UGT1A1 Promoter Genotype Correlates With SN-38 Pharmacokinetics, but Not Severe Toxicity in Patients Receiving Low-Dose Irinotecan
Published in Journal of clinical oncology (20-06-2007)“…To study the association between UDP-glucuronosyltransferase 1A1 (UGT1A1) genotypes and severe toxicity as well as irinotecan disposition in pediatric patients…”
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15
Bilateral Diffuse Nodular Pulmonary Ossification Mimicking Metastatic Disease in a Patient with Fibrolamellar Hepatocellular Carcinoma
Published in Children (Basel) (16-03-2021)“…Pulmonary ossification (PO) is a rare finding, characterized by mature bone formation in the lung parenchyma. We report a 20-year-old female patient diagnosed…”
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Tyrosine Kinase Inhibitor Enhances the Bioavailability of Oral Irinotecan in Pediatric Patients With Refractory Solid Tumors
Published in Journal of clinical oncology (20-09-2009)“…To assess the maximum-tolerated dosages (MTDs), and dose-limiting toxicities (DLTs) of the epidermal growth factor receptor inhibitor gefitinib and of…”
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Phase I Study of Depsipeptide in Pediatric Patients With Refractory Solid Tumors: A Children's Oncology Group Report
Published in Journal of clinical oncology (01-08-2006)“…To determine the maximum-tolerated dose (MTD), dose-limiting toxicities (DLT), pharmacokinetic profile, and pharmacodynamics of the histone deacetylase…”
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A phase 1/pilot study of radiofrequency ablation for the treatment of recurrent pediatric solid tumors
Published in Cancer (15-03-2009)“…BACKGROUND: This prospective study was designed to be the first to evaluate the toxicity of radiofrequency ablation (RFA) in patients with recurrent pediatric…”
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Current and Future Management Strategies for Relapsed or Progressive Hepatoblastoma
Published in Paediatric drugs (01-08-2012)“…Hepatoblastoma is the most common primary malignant neoplasm of the liver in children. Improvements in chemotherapy and surgical techniques have increased…”
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Disease control intervals in high‐risk neuroblastoma
Published in Cancer (15-06-2008)“…BACKGROUND. Current salvage therapy for recurrent high‐risk neuroblastoma is rarely curative. Assessment of the effectiveness of new, primarily cytostatic…”
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