Search Results - "FUNG, E. T"

Postoperative serum proteomic profiles may predict metastatic relapse in high-risk primary breast cancer patients receiving adjuvant chemotherapy by GONCALVES, A, ESTERNI, B, MENG, X.-Y, FUNG, E. T, BIRNBAUM, D, MARANINCHI, D, VIENS, P, BORG, J.-P, BERTUCCI, F, SAUVAN, R, CHABANNON, C, CUBIZOLLES, M, BARDOU, V. J, HOUVENAEGEL, G, JACQUEMIER, J, GRANJEAUD, S

“…A total of 30-50% of early breast cancer (EBC) patients considered as high risk using standard prognostic factors develop metastatic recurrence despite…”
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GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors by Dong, Hualing, O'Brien, Richard J, Fung, Eric T, Lanahan, Anthony A, Worley, Paul F, Huganir, Richard L

“…AMPA glutamate receptors mediate the majority of rapid excitatory synaptic transmission in the central nervous system and play a role in the synaptic…”
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Protein biochips for differential profiling by Fung, Eric T, Thulasiraman, Vanitha, Weinberger, Scot R, Dalmasso, Enrique A

“…Progress has been made in utilizing ProteinChip ® technology to profile and compare protein expression in normal and diseased states, particularly in the areas…”
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Splice Variant-Specific Interaction of the NMDA Receptor Subunit NR1 with Neuronal Intermediate Filaments by Ehlers, Michael D, Fung, Eric T, O'Brien, Richard J, Huganir, Richard L

“…NMDA receptors are excitatory neurotransmitter receptors critical for synaptic plasticity and neuronal development in the mammalian brain. These receptors are…”
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FKBP12 Binds the Inositol 1,4,5-Trisphosphate Receptor at Leucine-Proline (1400–1401) and Anchors Calcineurin to this FK506-like Domain by Cameron, Andrew M., Nucifora, Frederick C., Fung, Eric T., Livingston, David J., Aldape, Robert A., Ross, Christopher A., Snyder, Solomon H.

“…The immunophilin FKBP12 is one of the most abundant and conserved proteins in biology. It is the primary receptor for the immunosuppressant actions of the drug…”
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Rapsyn Clusters and Activates the Synapse-Specific Receptor Tyrosine Kinase MuSK by Gillespie, Susan K.H, Balasubramanian, Sudha, Fung, Eric T, Huganir, Richard L

“…Nerve-induced clustering of the nicotinic acetylcholine receptor (AChR) requires rapsyn, a synaptic peripheral membrane protein, as well as protein-tyrosine…”
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Proteomic strategies for biomarker identification: progress and challenges by Fung, E T, Wright, Jr, G L, Dalmasso, E A

“…The simplest definition of a biomarker is a molecule that indicates an alteration in physiology from normal. A more practical definition of a biomarker would…”
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Identification of a novel alternatively spliced septin by Fung, Eric T., Scheller, Richard H.

“…Septins are a family of cytoskeletal proteins involved in cytokinesis, targeting of proteins to specific sites on the plasma membrane, and cellular…”
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Characterization of the tyrosine phosphorylation and distribution of dystrobrevin isoforms by Balasubramanian, Sudha, Fung, Eric T, Huganir, Richard L

“…Dystrobrevin, a member of the dystrophin family of proteins, was initially identified as a major tyrosine phosphorylated synaptic protein in the electric organ…”
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LBA77Simultaneous multi-cancer detection and tissue of origin (TOO) localization using targeted bisulfite sequencing of plasma cell-free DNA (cfDNA) by Oxnard, G R, Klein, E A, Seiden, M V, Hubbell, E, Venn, O, Jamshidi, A, Zhang, N, Beausang, J F, Gross, S, Kurtzman, K N, Fung, E T, Allen, B, Fields, A P, Liu, H, Sekeres, M A, Richards, D A, Yu, P P, Aravanis, A M, Hartman, A-R, Liu, M C

“…Abstract Background Our previous discovery work identified whole-genome bisulfite sequencing as outperforming whole-genome and targeted sequencing approaches…”
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Identification of a dynein molecular motor component in Torpedo electroplax; binding and phosphorylation of Tctex-1 by Fyn by Mou, Tao, Kraas, Jonathan R., Fung, Eric T., Swope, Sheridan L.

“…The microtubule protein Tctex-1 was cloned from Torpedo electroplax, a biochemical model of the neuromuscular junction, using the unique domain of Fyn in the…”
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Laser desorption/Fourier transform mass spectrometry of steroids by Fung, E T, Wilkins, C L

“…Mass spectra of six representative underivatized steroids and three parent hydrocarbons were obtained using laser desorption/Fourier transform (LD/FT) mass…”
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Identification of a Torpedo homolog of Sam68 that interacts with the synapse organizing protein rapsyn by Fung, Eric T., Lanahan, Anthony, Worley, Paul, Huganir, Richard L.

“…Nicotinic acetylcholine receptors (nAChRs) are initially expressed diffusely on the surface of myotubes and, in response to neuronally derived factors, cluster…”
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Proteomic biomarkers for overall and progression-free survival in ovarian cancer patients by Høgdall, Estrid, Fung, Eric T., Christensen, Ib Jarle, Yip, Christine, Nedergaard, Lotte, Engelholm, Svend Aage, Risum, Signe, Petri, Anette Lykke, Lundvall, Lene, Lomas, Lee, Høgdall, Claus

“…Purpose: To determine if the level of apolipoprotein A1, hepcidin, transferrin, inter‐α trypsin IV internal fragment, transthyretin (TT), connective‐tissue…”
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Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer by ZHEN ZHANG, BAST, Robert C, BERCHUCK, Andrew, VAN HAAFTEN-DAY, Carolien, HACKER, Neville F, DE BRUIJN, Henk W. A, VAN DER ZEE, Ate G. J, JACOBS, Ian J, FUNG, Eric T, CHAN, Daniel W, YINHUA YU, JINONG LI, SOKOLL, Lori J, RAI, Alex J, ROSENZWEIG, Jason M, CAMERON, Bonnie, WANG, Young Y, MENG, Xiao-Ying

“…Early detection remains the most promising approach to improve long-term survival of patients with ovarian cancer. In a five-center case-control study, serum…”
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Use of a panel of proteomic markers to improve the sensitivity of CA125 for detecting stage I epithelial ovarian cancer by Clarke, C. H., Fung, E. T., Yip, C., Joy, C., Badgwell, D., Coombes, K. R., Zhang, Z., Lu, K. H., Bast, R. C.

“…Abstract only…”
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Comparison of proteomic biomarker panels in urine and serum for ovarian cancer diagnosis by Petri, Anette Lykke, Simonsen, Anja Hviid, Høgdall, Estrid, Christensen, Ib Jarle, Kjaer, Susanne Krüger, Yip, Christine, Risum, Signe, Pedersen, Anette Tønnes, Hartwell, Dorte, Fung, Eric T., Høgdall, Claus

“…Purpose: The purposes of this study were to confirm previously found candidate epithelial ovarian cancer biomarkers in urine and to compare a paired serum…”
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Independent Validation of Candidate Breast Cancer Serum Biomarkers Identified by Mass Spectrometry by Li, Jinong, Orlandi, Rosaria, White, C. Nicole, Rosenzweig, Jason, Zhao, Jing, Seregni, Ettore, Morelli, Daniele, Yu, Yinhua, Meng, Xiao-Ying, Zhang, Zhen, Davidson, Nancy E, Fung, Eric T, Chan, Daniel W

“…We previously selected a panel of 3 breast cancer biomarkers (BC1, BC2, and BC3) from serum samples collected at a single hospital based on their collective…”
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Classification of cancer types by measuring variants of host response proteins using SELDI serum assays by Fung, Eric T., Yip, Tai‐Tung, Lomas, Lee, Wang, Zheng, Yip, Christine, Meng, Xiao‐Ying, Lin, Shanhua, Zhang, Fujun, Zhang, Zhen, Chan, Daniel W., Weinberger, Scot R.

“…Protein expression profiling has been increasingly used to discover and characterize biomarkers that can be used for diagnostic, prognostic or therapeutic…”
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ProteinChip® Clinical Proteomics: Computational Challenges and Solutions by Eric T. Fung, Cynthia Enderwick

“…ProteinChip® technology, a suite of analytical tools that includes retentate chromatography, on-chip protein characterization, and multivariate analysis,…”
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