Search Results - "FULL, Florian"

Pioneer factors in viral infection by Neugebauer, Eva, Bastidas-Quintero, Aura M, Weidl, Daniel, Full, Florian

“…Pioneer factors are transcription factors sharing the fascinating ability to bind to compact chromatin and thereby alter its transcriptional fate. Most pioneer…”
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Antagonism of the Phosphatase PP1 by the Measles Virus V Protein Is Required for Innate Immune Escape of MDA5 by Davis, Meredith E., Wang, May K., Rennick, Linda J., Full, Florian, Gableske, Sebastian, Mesman, Annelies W., Gringhuis, Sonja I., Geijtenbeek, Teunis B.H., Duprex, W. Paul, Gack, Michaela U.

“…The cytosolic sensor MDA5 is crucial for antiviral innate immune defense against various RNA viruses including measles virus; as such, many viruses…”
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Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H by Schütz, Martin, Müller, Regina, Socher, Eileen, Wangen, Christina, Full, Florian, Wyler, Emanuel, Wong, Diana, Scherer, Myriam, Stamminger, Thomas, Chou, Sunwen, Rawlinson, William D., Hamilton, Stuart T., Sticht, Heinrich, Marschall, Manfred

“…The complex host interaction network of human cytomegalovirus (HCMV) involves the regulatory protein kinase pUL97, which represents a viral cyclin-dependent…”
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Redirecting T cells to Ewing's sarcoma family of tumors by a chimeric NKG2D receptor expressed by lentiviral transduction or mRNA transfection by Lehner, Manfred, Götz, Gabriel, Proff, Julia, Schaft, Niels, Dörrie, Jan, Full, Florian, Ensser, Armin, Muller, Yves A, Cerwenka, Adelheid, Abken, Hinrich, Parolini, Ornella, Ambros, Peter F, Kovar, Heinrich, Holter, Wolfgang

“…We explored the possibility to target Ewing's sarcoma family of tumors (ESFT) by redirecting T cells. To this aim, we considered NKG2D-ligands (NKG2D-Ls) as…”
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Herpesvirus Saimiri Antagonizes Nuclear Domain 10-Instituted Intrinsic Immunity via an ORF3-Mediated Selective Degradation of Cellular Protein Sp100 by Full, Florian, Reuter, Nina, Zielke, Katrin, Stamminger, Thomas, Ensser, Armin

“…In recent studies, the nuclear domain 10 (ND10) components PML, Sp100, human Daxx (hDaxx), and ATRX were identified to be cellular restriction factors that are…”
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CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs by Xiao, Han, Wyler, Emanuel, Milek, Miha, Grewe, Bastian, Kirchner, Philipp, Ekici, Arif, Silva, Ana Beatriz Oliveira Villela, Jungnickl, Doris, Full, Florian, Thomas, Marco, Landthaler, Markus, Ensser, Armin, Überla, Klaus

“…The HIV-1 Rev protein is a nuclear export factor for unspliced and incompletely spliced HIV-1 RNAs. Without Rev, these intron-retaining RNAs are trapped in the…”
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Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies by Scherer, Myriam, Read, Clarissa, Neusser, Gregor, Kranz, Christine, Kuderna, Anna K, Müller, Regina, Full, Florian, Wörz, Sonja, Reichel, Anna, Schilling, Eva-Maria, Walther, Paul, Stamminger, Thomas

“…PML nuclear bodies (PML-NBs) are dynamic interchromosomal macromolecular complexes implicated in epigenetic regulation as well as antiviral defense. During…”
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Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity by Full, Florian, Jungnickl, Doris, Reuter, Nina, Bogner, Elke, Brulois, Kevin, Scholz, Brigitte, Stürzl, Michael, Myoung, Jinjong, Jung, Jae U, Stamminger, Thomas, Ensser, Armin

“…Nuclear domain 10 (ND10) components are restriction factors that inhibit herpesviral replication. Effector proteins of different herpesviruses can antagonize…”
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Delicate coordination of TRIM21’s dual activity in virus neutralization and signaling by Full, Florian, Gack, Michaela U.

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Construction and Characterization of a High-Capacity Replication-Competent Murine Cytomegalovirus Vector for Gene Delivery by Riedl, André, Bojková, Denisa, Tan, Jiang, Jeney, Ábris, Larsen, Pia-Katharina, Jeney, Csaba, Full, Florian, Kalinke, Ulrich, Ruzsics, Zsolt

“…We investigated the basic characteristics of a new murine cytomegalovirus (MCMV) vector platform. Using BAC technology, we engineered replication-competent…”
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Gammaherpesviral Tegument Proteins, PML-Nuclear Bodies and the Ubiquitin-Proteasome System by Full, Florian, Hahn, Alexander S, Großkopf, Anna K, Ensser, Armin

“…Gammaherpesviruses like Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) subvert the ubiquitin proteasome system for their own…”
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Genome-Wide Histone Acetylation Profiling of Herpesvirus saimiri in Human T Cells upon Induction with a Histone Deacetylase Inhibitor by ALBERTER, Barbara, VOGEL, Benjamin, LENGENFELDER, Doris, FULL, Florian, ENSSER, Armin

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T Cells Engineered with a Cytomegalovirus-Specific Chimeric Immunoreceptor by FULL, Florian, LEHNER, Manfred, THONN, Veronika, GOETZ, Gabriel, SCHOLZ, Brigitte, KAUFMANN, Kerstin B, MACH, Michael, ABKEN, Hinrich, HOLTER, Wolfgang, ENSSER, Armin

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The Insulator Protein CTCF Binding Sites in the orf73/LANA Promoter Region of Herpesvirus Saimiri Are Involved in Conferring Episomal Stability in Latently Infected Human T Cells by ZIELKE, Katrin, FULL, Florian, TEUFERT, Natascha, SCHMIDT, Monika, MÜLLER-FLECKENSTEIN, Ingrid, ALBERTER, Barbara, ENSSER, Armin

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Early Nuclear Events after Herpesviral Infection by Full, Florian, Ensser, Armin

“…Herpesviruses are important pathogens that can cause significant morbidity and mortality in the human population. Herpesviruses have a double-stranded DNA…”
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The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses by de Jong, Sarah Jill, Créquer, Amandine, Matos, Irina, Hum, David, Gunasekharan, Vignesh, Lorenzo, Lazaro, Jabot-Hanin, Fabienne, Imahorn, Elias, Arias, Andres A, Vahidnezhad, Hassan, Youssefian, Leila, Markle, Janet G, Patin, Etienne, D'Amico, Aurelia, Wang, Claire Q F, Full, Florian, Ensser, Armin, Leisner, Tina M, Parise, Leslie V, Bouaziz, Matthieu, Maya, Nataly Portilla, Cadena, Xavier Rueda, Saka, Bayaki, Saeidian, Amir Hossein, Aghazadeh, Nessa, Zeinali, Sirous, Itin, Peter, Krueger, James G, Laimins, Lou, Abel, Laurent, Fuchs, Elaine, Uitto, Jouni, Franco, Jose Luis, Burger, Bettina, Orth, Gérard, Jouanguy, Emmanuelle, Casanova, Jean-Laurent

“…Patients with epidermodysplasia verruciformis (EV) and biallelic null mutations of (encoding EVER1) or (EVER2) are selectively prone to disseminated skin…”
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TRIM23 mediates virus-induced autophagy via activation of TBK1 by Sparrer, Konstantin M. J., Gableske, Sebastian, Zurenski, Matthew A., Parker, Zachary M., Full, Florian, Baumgart, Gavin J., Kato, Jiro, Pacheco-Rodriguez, Gustavo, Liang, Chengyu, Pornillos, Owen, Moss, Joel, Vaughan, Martha, Gack, Michaela U.

“…Autophagy and interferon (IFN)-mediated innate immunity are critical antiviral defence mechanisms, and recent evidence indicated that tripartite motif (TRIM)…”
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Cytomegalovirus-Infected Cells Resist T Cell Mediated Killing in an HLA-Recognition Independent Manner by Proff, Julia, Walterskirchen, Christian, Brey, Charlotte, Geyeregger, Rene, Full, Florian, Ensser, Armin, Lehner, Manfred, Holter, Wolfgang

“…In order to explore the potential of HLA-independent T cell therapy for human cytomegalovirus (HCMV) infections, we developed a chimeric antigen receptor (CAR)…”
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Prostaglandin E2: the Villain in the Host Response to Influenza Virus by Full, Florian, Gack, Michaela U.

“…Prostaglandins are lipid mediators that are involved in a plethora of biological processes. In this issue of Immunity, Coulombe et al. (2014) report that…”
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Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity by Full, Florian, van Gent, Michiel, Sparrer, Konstantin M. J., Chiang, Cindy, Zurenski, Matthew A., Scherer, Myriam, Brockmeyer, Norbert H., Heinzerling, Lucie, Stürzl, Michael, Korn, Klaus, Stamminger, Thomas, Ensser, Armin, Gack, Michaela U.

“…Tripartite motif (TRIM) proteins mediate antiviral host defences by either directly targeting viral components or modulating innate immune responses. Here we…”
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