Search Results - "FUKUE, Yoshihiko"
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Ghrelin Directly Regulates Bone Formation
Published in Journal of bone and mineral research (01-05-2005)“…To clarify the role of ghrelin in bone metabolism, we examined the effect of ghrelin in vitro and in vivo. Ghrelin and its receptor, GHS‐R1a, were identified…”
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Ingested Medium-Chain Fatty Acids Are Directly Utilized for the Acyl Modification of Ghrelin
Published in Endocrinology (Philadelphia) (01-05-2005)“…Ghrelin, an acylated brain and gut peptide, is primarily produced by endocrine cells of the gastric mucosa for secretion into the circulation. The major active…”
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Molecular Forms of Hypothalamic Ghrelin and Its Regulation by Fasting and 2-Deoxy-d-Glucose Administration
Published in Endocrinology (Philadelphia) (01-06-2005)“…Ghrelin, an endogenous ligand for the GH secretagogue receptor, is a hormone expressed in stomach and other tissues, such as hypothalamus, testis, and…”
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Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice
Published in Behavioural brain research (05-01-2010)“…To examine the effects of deletion of gangliosides on the nervous system by avoiding masking effects with the remaining structures, we established double…”
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Regulation of gonadotropin secretion and puberty onset by neuromedin U
Published in FEBS letters (12-06-2006)“…Neuromedin U (NMU), an anorexigenic peptide, was originally isolated from porcine spinal cord in 1985. As NMU is abundant in the anterior pituitary gland, we…”
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Disruption of the Prepulse Inhibition of the Startle Reflex in Vasopressin V1b Receptor Knockout Mice: Reversal by Antipsychotic Drugs
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2005)“…In the present study, we investigated whether mice lacking the arginine vasopressin (AVP) V1b receptor (V1bR) exhibit deficits of prepulse inhibition (PPI) of…”
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V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial maze
Published in Neuroscience letters (19-02-2004)“…In this study, we examined the performance of vasopressin V1a receptor (V1aR) and vasopressin V1b receptor (V1bR) knockout (KO) mice compared to wild-type (WT)…”
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Characteristics of behavioral abnormalities in α1d-adrenoceptors deficient mice
Published in Behavioural brain research (01-07-2004)Get full text
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The Pharmacological Characterization of Attentional Processes Using a Two-lever Choice Reaction Time Task in Rats
Published in Biological & pharmaceutical bulletin (01-12-2002)“…Activating the noradrenergic and cholinergic systems is known to enhance attentional processes, while stimulating dopaminergic, serotonergic, and GABAergic…”
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Ghrelin deficiency does not influence feeding performance
Published in Regulatory peptides (10-01-2008)“…Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that is synthesized predominantly in the stomach. Previous studies demonstrated…”
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Journal Article Conference Proceeding -
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Reduced motor and sensory functions and emotional response in GM3-only mice: Emergence from early stage of life and exacerbation with aging
Published in Behavioural brain research (02-03-2009)“…Sialic acid-containing glycosphingolipids (gangliosides) have been believed to play a role in the regulation and protection of nervous tissues. To clarify…”
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Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway
Published in Nature medicine (01-10-2004)“…Neuromedin U (NMU) is a hypothalamic neuropeptide that regulates body weight and composition. Here we show that mice lacking the gene encoding NMU (Nmu(-/-)…”
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Characteristics of behavioral abnormalities in alpha1d-adrenoceptors deficient mice
Published in Behavioural brain research (09-07-2004)“…To investigate the functional role of alpha1d-adrenergic receptor (alpha1d-AR) in the CNS, we have generated mutant mice lacking the alpha1d-AR using a gene…”
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Characteristics of behavioral abnormalities in α 1d-adrenoceptors deficient mice
Published in Behavioural brain research (2004)“…To investigate the functional role of α 1d-adrenergic receptor (α 1d-AR) in the CNS, we have generated mutant mice lacking the α 1d-AR using a gene targeting…”
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