Search Results - "FUKUDA, YU"
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Mental Health and Physical Activity among Children and Adolescents during the COVID-19 Pandemic
Published in The Tohoku Journal of Experimental Medicine (2021)“…Coronavirus disease 2019 (COVID-19) is causing disruptions in the global social system. Japanese children and adolescents have had their schools closed,…”
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Obstacles to Brain Tumor Therapy: Key ABC Transporters
Published in International journal of molecular sciences (27-11-2017)“…The delivery of cancer chemotherapy to treat brain tumors remains a challenge, in part, because of the inherent biological barrier, the blood-brain barrier…”
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Three-Dimensional Measurement for Revitalization of Intangible Cultural Properties After Disasters
Published in Journal of disaster research (01-12-2019)“…Various traditional festivals have taken place in most of the community in the coastal areas of the Tohoku region before the 2011 Great East Japan earthquake…”
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Neuroprotection by Neurotropin through Crosstalk of Neurotrophic and Innate Immune Receptors in PC12 Cells
Published in International journal of molecular sciences (04-09-2020)“…Infected or damaged tissues release multiple "alert" molecules such as alarmins and damage-associated molecular patterns (DAMPs) that are recognized by innate…”
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Linking affected community and academic knowledge: a community-based participatory research framework based on a Shichigahama project
Published in Scientific reports (28-08-2024)“…Earthquakes that cause extensive damage occur frequently in Japan, the most recent being the Noto Peninsula earthquake on January 1, 2024. To facilitate such a…”
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Establishment of a post-disaster healthcare information booklet for the Turkey–Syrian earthquake, based on past disasters
Published in Scientific reports (18-01-2024)“…The scientific evidence based on experiences with past disasters points to the possibility of the occurrence of future mental health issues among those who…”
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The transcription factor Hhex regulates inflammation-related genes in microglia
Published in Journal of pharmacological sciences (01-07-2022)“…Microglia have diverse physiological and pathological functions. However, the transcriptional mechanisms remain elusive. Here we sought new transcription…”
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Publisher Correction: The net electrostatic potential and hydration of ABCG2 affect substrate transport
Published in Nature communications (17-10-2024)Get full text
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Levetiracetam versus fosphenytoin as a second-line treatment after diazepam for adult convulsive status epilepticus: a multicentre non-inferiority randomised control trial
Published in Journal of neurology, neurosurgery and psychiatry (01-01-2023)“…ObjectiveStatus epilepticus (SE) is an emergency condition for which rapid and secured cessation is crucial. Although fosphenytoin (FPHT) is recommended as a…”
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The net electrostatic potential and hydration of ABCG2 affect substrate transport
Published in Nature communications (18-08-2023)“…ABCG2 is a medically important ATP-binding cassette transporter with crucial roles in the absorption and distribution of chemically-diverse toxins and drugs,…”
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Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters
Published in PloS one (13-07-2021)“…Abcg2/Bcrp and Abcb1a/Pgp are xenobiotic efflux transporters limiting substrate permeability in the gastrointestinal system and brain, and increasing renal and…”
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The role of ATP-binding Cassette subfamily B member 6 in the inner ear
Published in Nature communications (18-11-2024)“…ABCB6 has been implicated in dyschromatosis universalis hereditaria, a condition characterized by hyperpigmented and hypopigmented skin macules. Dyschromatosis…”
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Identification of a mammalian mitochondrial porphyrin transporter
Published in Nature (05-10-2006)“…The movement of anionic porphyrins (for example, haem) across intracellular membranes is crucial to many biological processes, but their mitochondrial…”
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The ABCC4 membrane transporter modulates platelet aggregation
Published in Blood (12-11-2015)“…Controlling the activation of platelets is a key strategy to mitigate cardiovascular disease. Previous studies have suggested that the ATP-binding cassette…”
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Life and Stress of Japanese Children and Adolescents During the Prolonged Coronavirus Disease 2019 (COVID-19) Pandemic
Published in Journal of disaster research (20-01-2023)“…This study surveyed adult web monitor enrollees about the lives of and stress experienced by Japanese children and adolescents during the prolonged coronavirus…”
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Life Alterations and Stress During the COVID-19 Pandemic in Japan: Two-Time Comparison
Published in Journal of disaster research (30-01-2022)“…No other infectious disease that has had a long-lasting impact on humanity in recent times has caused as much hardship as the coronavirus disease, COVID-19…”
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L-PGDS-PGD2-DP1 Axis Regulates Phagocytosis by CD36 + MGs/MΦs That Are Exclusively Present Within Ischemic Areas After Stroke
Published in Cells (Basel, Switzerland) (20-10-2024)“…Brain injuries, such as ischemic stroke, cause cell death. Although phagocytosis of cellular debris is mainly performed by microglia/macrophages (MGs/MΦs),…”
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The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6
Published in Nature communications (10-08-2016)“…Hereditary porphyrias are caused by mutations in genes that encode haem biosynthetic enzymes with resultant buildup of cytotoxic metabolic porphyrin…”
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An unexpected protein interaction promotes drug resistance in leukemia
Published in Nature communications (16-11-2017)“…The overall survival of patients with acute myeloid leukemia (AML) is poor and identification of new disease-related therapeutic targets remains a major goal…”
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