Search Results - "FUKUCHI, Y"

Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients by Sakurai, M, Kunimoto, H, Watanabe, N, Fukuchi, Y, Yuasa, S, Yamazaki, S, Nishimura, T, Sadahira, K, Fukuda, K, Okano, H, Nakauchi, H, Morita, Y, Matsumura, I, Kudo, K, Ito, E, Ebihara, Y, Tsuji, K, Harada, Y, Harada, H, Okamoto, S, Nakajima, H

“…Somatic mutation of RUNX1 is implicated in various hematological malignancies, including myelodysplastic syndrome and acute myeloid leukemia (AML), and…”
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Tiotropium 5 μg via Respimat and 18 μg via HandiHaler; efficacy and safety in Japanese COPD patients by Ichinose, M, Fujimoto, T, Fukuchi, Y

“…Summary Background and objectives To compare the efficacy and safety of tiotropium inhaled via Respimat® Soft Mist Inhaler, a multidose propellant-free inhaler…”
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Sustained 24-h efficacy of NVA237, a once-daily long-acting muscarinic antagonist, in COPD patients by Verkindre, C, Fukuchi, Y, Flémale, A, Takeda, A, Overend, T, Prasad, N, Dolker, M

“…Summary NVA237 is a once-daily inhaled long-acting muscarinic antagonist in development for the treatment of COPD. This randomized, double-blind,…”
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The efficacy and safety of combined tiotropium and olodaterol via the Respimat(®) inhaler in patients with COPD: results from the Japanese sub-population of the Tonado(®) studies by Ichinose, Masakazu, Taniguchi, Hiroyuki, Takizawa, Ayako, Grönke, Lars, Loaiza, Lazaro, Voß, Florian, Zhao, Yihua, Fukuchi, Yoshinosuke

“…The efficacy and safety of once-daily tiotropium + olodaterol (T+O) maintenance treatment was demonstrated in the large, multinational, replicate, randomized,…”
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COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan by Igarashi, Ataru, Fukuchi, Yoshinosuke, Hirata, Kazuto, Ichinose, Masakazu, Nagai, Atsushi, Nishimura, Masaharu, Yoshisue, Hajime, Ohara, Kenichi, Gruenberger, Jean-Bernard

“…COPD remains a major health problem in Japan. Patients with COPD experience a reduced quality of life (QoL) and have a higher chance of work impairment and…”
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Characteristics of all-optical ultrafast gate switches using cascade of second-harmonic generation and difference frequency mixing in quasi-phase-matched lithium niobate waveguides by Fukuchi, Y., Akaike, M., Maeda, J.

“…In all-optical gate switches that employ the cascade of second-harmonic generation and difference frequency mixing in quasi-phase-matched (QPM) lithium niobate…”
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Prevention of COPD exacerbation by lysozyme: a double-blind, randomized, placebo-controlled study by Fukuchi, Yoshinosuke, Tatsumi, Koichiro, Inoue, Hiromasa, Sakata, Yukinori, Shibata, Kai, Miyagishi, Hideaki, Marukawa, Yasuhiro, Ichinose, Masakazu

“…Lysozyme (mucopeptide N-acetyl-muramyl hydrolase) is widely used as a mucolytic and anti-inflammatory agent in Japan. We evaluated the effects of long-term…”
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Increasing COPD awareness by ZIELINSKI, J, BEDNAREK, M, ZHENG, J. P, ZHONG, N. S, IP, M. S. M, VERMEIRE, P. A, GORECKA, D, VIEGI, G, HURD, S. S, FUKUCHI, Y, LAI, C. K. W, RAN, P. X, KO, F. W. S, LIU, S. M

“…Early diagnosis and smoking cessation are the only available methods to stop the progression of chronic obstructive pulmonary disease (COPD). The aim of this…”
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COPD exacerbations: the importance of a standard definition by Pauwels, R, Calverley, P, Buist, A.S, Rennard, S, Fukuchi, Y, Stahl, E, Löfdahl, C.G

“…Efforts to assess the efficacy of new therapies in the treatment of acute exacerbations of chronic obstructive pulmonary disease (COPD) have been hampered by…”
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Glutathione S-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease by Ishii, T, Matsuse, T, Teramoto, S, Matsui, H, Miyao, M, Hosoi, T, Takahashi, H, Fukuchi, Y, Ouchi, Y

“…BACKGROUND Enzymes that contribute to the local detoxification in alveoli and bronchioles have an important role in the defence mechanism against tobacco…”
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Calculation of gestational age in late second and third trimesters by ex vivo magnetic resonance spectroscopy of amniotic fluid by Cohn, Brad R., MD, Fukuchi, Emily Y., MD, MPH, Joe, Bonnie N., MD, PhD, Swanson, Mark G., PhD, Kurhanewicz, John, PhD, Yu, Jingwei, PhD, MD, Caughey, Aaron B., MD, PhD, MPH

“…Objective The purpose of this study was to develop a reliable model for the calculation of gestational age (GA) in second and third trimesters with the use of…”
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Role of Osteopontin in the Pathogenesis of Bleomycin-Induced Pulmonary Fibrosis by Takahashi, Fumiyuki, Takahashi, Kazuhisa, Okazaki, Tatsuma, Maeda, Kayo, Ienaga, Hiroki, Maeda, Masahiro, Kon, Shigeyuki, Uede, Toshimitsu, Fukuchi, Yoshinosuke

“…Pulmonary fibrosis is initiated by migration, adhesion, and proliferation of fibroblasts. Osteopontin (OPN) is one of the cytokines produced by activated…”
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Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis by Sato, Teruhiko, Seyama, Kuniaki, Fujii, Hiroaki, Maruyama, Hiroshi, Setoguchi, Yasuhiro, Iwakami, Shin-ichiro, Fukuchi, Yoshinosuke, Hino, Okio

“…Pulmonary lymphangioleiomyomatosis (LAM) is a destructive lung disease characterized by a diffuse hamartomatous proliferation of smooth muscle cells (LAM…”
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Bone morphogenetic protein-2 induces apoptosis in human myeloma cells with modulation of STAT3 by Kawamura, Chiharu, Kizaki, Masahiro, Yamato, Kenji, Uchida, Hideo, Fukuchi, Yumi, Hattori, Yutaka, Koseki, Takeyoshi, Nishihara, Tatsuji, Ikeda, Yasuo

“…Bone morphogenetic proteins (BMPs), members of the transforming growth factor (TGF)–β superfamily, are a group of related proteins that are capable of inducing…”
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Association of Gc-globulin variation with susceptibility to COPD and diffuse panbronchiolitis by Ishii, T, Keicho, N, Teramoto, S, Azuma, A, Kudoh, S, Fukuchi, Y, Ouchi, Y, Matsuse, T

“…Chronic obstructive pulmonary disease (COPD) and diffuse panbronchiolitis (DPB) are both characterized by chronic airflow limitation. Although the aetiology of…”
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Novel design method for all-optical ultrafast gate switches using cascaded second-order nonlinear effect in quasi-phase matched LiNbO3 devices by Fukuchi, Y., Kikuchi, K.

“…The authors propose a novel method of designing all-optical ultrafast gate switches that employ the cascade of the second harmonic generation and difference…”
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Numerical Study on High-Speed Optical RZ Pulse Transmission in Fiber Link With Dispersion-Slope Management by Maeda, J.., Fukuchi, Y..

“…This paper presents a numerical study of the transmission of a 160-Gb/s return-to-zero pulse train in a fiber link, in which both the dispersion and the…”
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VEGF regulates the proliferation of acid-exposed alveolar lining epithelial cells by Ohwada, A, Yoshioka, Y, Iwabuchi, K, Nagaoka, I, Dambara, T, Fukuchi, Y

“…Background: Acid induced pneumonitis resulting in acute respiratory distress syndrome (ARDS) is characterised by increased alveolar permeability and…”
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Neither IL-1 β, IL-1 receptor antagonist, nor TNF- α polymorphisms are associated with susceptibility to COPD by ISHII, T., MATSUSE, T., TERAMOTO, S., MATSUI, H., MIYAO, M., HOSOI, T., TAKAHASHI, H., FUKUCHI, Y., OUCHI, Y.

“…The cytokines that contribute to airway inflammation, including interleukin-1 β (IL-1β )and tumour necrosis factor α (TNF α), might have key roles in the…”
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Arsenic trioxide (As2O3)-induced apoptosis and differentiation in retinoic acid-resistant acute promyelocytic leukemia model in hGM-CSF-producing transgenic SCID mice by KINJO, K, KIZAKI, M, IKEDA, Y, MUTO, A, FUKUCHI, Y, UMEZAWA, A, YAMATO, K, NISHIHARA, T, HATA, J, ITO, M, UEYAMA, Y

“…Recent clinical studies in China and USA showed that arsenic trioxide (As2O3) is an effective treatment of acute promyelocytic leukemia (APL) patients…”
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