Search Results - "FUKASAWA, Kenji"

Centrosome amplification, chromosome instability and cancer development by Fukasawa, Kenji

“…During mitosis, two centrosomes form spindle poles and direct the formation of bipolar mitotic spindles, which is an essential event for accurate chromosome…”
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Characteristics of long working hours and subsequent psychological and physical responses: JNIOSH cohort study by Ochiai, Yuko, Takahashi, Masaya, Matsuo, Tomoaki, Sasaki, Takeshi, Sato, Yuki, Fukasawa, Kenji, Araki, Tsuyoshi, Otsuka, Yasumasa

“…This study aimed to examine the prospective association among objectively measured average working hours (AWHs), frequency of long working hours (FLWHs;…”
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SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities by Peng, Lirong, Yuan, Zhigang, Ling, Hongbo, Fukasawa, Kenji, Robertson, Keith, Olashaw, Nancy, Koomen, John, Chen, Jiandong, Lane, William S., Seto, Edward

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Study profile: protocol outline and study perspectives of the cohort by the National Institute of Occupational Safety and Health, Japan (JNIOSH cohort) by SATO, Yuki, TAKAHASHI, Masaya, OCHIAI, Yuko, MATSUO, Tomoaki, SASAKI, Takeshi, FUKASAWA, Kenji, ARAKI, Tsuyoshi, TSUCHIYA, Masao, Group of JNIOSH cohort study

“…How work burden affects physical and mental health has already been studied extensively; however, many issues have remained unexamined. In 2017, we commenced a…”
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Validation of the Karolinska sleepiness scale against performance and EEG variables by Kaida, Kosuke, Takahashi, Masaya, Åkerstedt, Torbjörn, Nakata, Akinori, Otsuka, Yasumasa, Haratani, Takashi, Fukasawa, Kenji

“…The Karolinska sleepiness scale (KSS) is frequently used for evaluating subjective sleepiness. The main aim of the present study was to investigate the…”
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Ubiquitinated Sirtuin 1 (SIRT1) Function Is Modulated during DNA Damage-induced Cell Death and Survival by Peng, Lirong, Yuan, Zhigang, Li, Yixuan, Ling, Hongbo, Izumi, Victoria, Fang, Bin, Fukasawa, Kenji, Koomen, John, Chen, Jiandong, Seto, Edward

“…Downstream signaling of physiological and pathological cell responses depends on post-translational modification such as ubiquitination. The mechanisms…”
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Loss of p53 and centrosome hyperamplification by Tarapore, Pheruza, Fukasawa, Kenji

“…Loss or mutational inactivation of p53 has been shown to lead to abnormal amplification of centrosomes through deregulation of the centrosome duplication cycle…”
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Health problems associated with single, multiple, and the frequency of months of objectively measured long working hours: a cohort study by the National Institute of Occupational Safety and Health, Japan by Ochiai, Yuko, Takahashi, Masaya, Matsuo, Tomoaki, Sasaki, Takeshi, Sato, Yuki, Fukasawa, Kenji, Araki, Tsuyoshi, Otsuka, Yasumasa

“…Purpose We aimed to examine the prospective associations of monthly working hours measured in a month, the 6-month averaged hours, and the frequency of long…”
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Objective and subjective working hours and their roles on workers’ health among Japanese employees by OCHIAI, Yuko, TAKAHASHI, Masaya, MATSUO, Tomoaki, SASAKI, Takeshi, FUKASAWA, Kenji, ARAKI, Tsuyoshi, TSUCHIYA, Masao, OTSUKA, Yasumasa

“…This study investigated the correlation between objective and subjective working hours (OWH and SWH, respectively) and their relation to the workers’ health…”
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SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60 by Peng, Lirong, Ling, Hongbo, Yuan, Zhigang, Fang, Bin, Bloom, Gregory, Fukasawa, Kenji, Koomen, John, Chen, Jiandong, Lane, William S., Seto, Edward

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Analysis of centrosome localization of BRCA1 and its activity in suppressing centrosomal aster formation by Tarapore, Pheruza, Hanashiro, Kazuhiko, Fukasawa, Kenji

“…BRCA1, a product of a familial breast and ovarian cancer susceptibility gene, localizes to centrosomes and physically interacts with γ-tubulin, a key…”
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Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation by Kanai, Masayuki, Miwa, Masanao, Hanashiro, Kazuhiko, Kim, Song-Hee, Hanai, Shuji, Fukasawa, Kenji, Boulares, A. Hamid

“…Poly(ADP-ribose) polymerase 1 (PARP-1) and p53 are two key proteins in the DNA-damage response. Although PARP-1 is known to poly(ADP-ribosyl)ate p53, the role…”
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Development of Risk Score for Predicting 3-Year Incidence of Type 2 Diabetes: Japan Epidemiology Collaboration on Occupational Health Study by Nanri, Akiko, Nakagawa, Tohru, Kuwahara, Keisuke, Yamamoto, Shuichiro, Honda, Toru, Okazaki, Hiroko, Uehara, Akihiko, Yamamoto, Makoto, Miyamoto, Toshiaki, Kochi, Takeshi, Eguchi, Masafumi, Murakami, Taizo, Shimizu, Chii, Shimizu, Makiko, Tomita, Kentaro, Nagahama, Satsue, Imai, Teppei, Nishihara, Akiko, Sasaki, Naoko, Hori, Ai, Sakamoto, Nobuaki, Nishiura, Chihiro, Totsuzaki, Takafumi, Kato, Noritada, Fukasawa, Kenji, Huanhuan, Hu, Akter, Shamima, Kurotani, Kayo, Kabe, Isamu, Mizoue, Tetsuya, Sone, Tomofumi, Dohi, Seitaro

“…Risk models and scores have been developed to predict incidence of type 2 diabetes in Western populations, but their performance may differ when applied to…”
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Suppression of centrosome duplication and amplification by deacetylases by Ling, Hongbo, Peng, Lirong, Seto, Edward, Fukasawa, Kenji

“…Centrosome duplication is controlled both negatively and positively by a number of proteins. The activities and stabilities of those regulatory proteins are in…”
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Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89 by Reboutier, David, Troadec, Marie-Bérengère, Cremet, Jean-Yves, Fukasawa, Kenji, Prigent, Claude

“…Aurora A (AurA) is a major mitotic protein kinase involved in centrosome maturation and spindle assembly. Nucleophosmin/B23 (NPM) is a pleiotropic nucleolar…”
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Interaction between ROCK II and Nucleophosmin/B23 in the Regulation of Centrosome Duplication by Ma, Zhiyong, Kanai, Masayuki, Kawamura, Kenji, Kaibuchi, Kozo, Ye, Keqiang, Fukasawa, Kenji

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Smoking, Smoking Cessation, and the Risk of Type 2 Diabetes among Japanese Adults: Japan Epidemiology Collaboration on Occupational Health Study by Akter, Shamima, Okazaki, Hiroko, Kuwahara, Keisuke, Miyamoto, Toshiaki, Murakami, Taizo, Shimizu, Chii, Shimizu, Makiko, Tomita, Kentaro, Nagahama, Satsue, Eguchi, Masafumi, Kochi, Takeshi, Imai, Teppei, Nishihara, Akiko, Sasaki, Naoko, Nakagawa, Tohru, Yamamoto, Shuichiro, Honda, Toru, Uehara, Akihiko, Yamamoto, Makoto, Hori, Ai, Sakamoto, Nobuaki, Nishiura, Chihiro, Nishiura, Chiro, Totsuzaki, Takafumi, Kato, Noritada, Fukasawa, Kenji, Pham, Ngoc M, Kurotani, Kayo, Nanri, Akiko, Kabe, Isamu, Mizoue, Tetsuya, Sone, Tomofumi, Dohi, Seitaro

“…To examine the association of smoking status, smoking intensity, and smoking cessation with the risk of type 2 diabetes (T2D) using a large database. The…”
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Oncogenes and tumour suppressors take on centrosomes by Fukasawa, Kenji

“…Chromosome instability, which is equated to mitotic defects and consequential chromosome segregation errors, provides a formidable basis for the acquisition of…”
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Correction: Development of Risk Score for Predicting 3-Year Incidence of Type 2 Diabetes: Japan Epidemiology Collaboration on Occupational Health Study by Nanri, Akiko, Nakagawa, Tohru, Kuwahara, Keisuke, Yamamoto, Shuichiro, Honda, Toru, Okazaki, Hiroko, Uehara, Akihiko, Yamamoto, Makoto, Miyamoto, Toshiaki, Kochi, Takeshi, Eguchi, Masafumi, Murakami, Taizo, Shimizu, Chii, Shimizu, Makiko, Tomita, Kentaro, Nagahama, Satsue, Imai, Teppei, Nishihara, Akiko, Sasaki, Naoko, Hori, Ai, Sakamoto, Nobuaki, Nishiura, Chihiro, Totsuzaki, Takafumi, Kato, Noritada, Fukasawa, Kenji, Hu, Huanhuan, Akter, Shamima, Kurotani, Kayo, Kabe, Isamu, Mizoue, Tetsuya, Sone, Tomofumi, Dohi, Seitaro

“…[This corrects the article DOI: 10.1371/journal.pone.0142779.]…”
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Oncogenic RAS Induces Accelerated Transition through G2/M and Promotes Defects in the G2 DNA Damage and Mitotic Spindle Checkpoints by Knauf, Jeffrey A., Ouyang, Bin, Knudsen, Erik S., Fukasawa, Kenji, Babcock, George, Fagin, James A.

“…Activating mutations of RAS are prevalent in thyroid follicular neoplasms, which commonly have chromosomal losses and gains. In thyroid cells, acute expression…”
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