Search Results - "FUKAMI, Masaharu"

Expression of Ovotransferrin Enhances Tolerance of Yeast Cells toward Oxidative Stress by Ibrahim, Hisham R, Hozono, Akiko, Fukami, Masaharu, Shaban, Mohamed A, Miyata, Takeshi

“…Recently, we found that ovotransferrin (OTf) undergoes distinct self-cleavage in a redox-dependent process and exhibited in vitro superoxide dismutase…”
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The mechanism of lack of hypocholesterolemic effects of pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rats by Fujioka, Tomoyuki, Nara, Futoshi, Tsujita, Yoshio, Fukushige, Junichiro, Fukami, Masaharu, Kuroda, Masao

“…In order to clarify the reason why pravastatin, a 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitor, did not show hypocholesterolemic effects in rats,…”
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Effects of HMG-CoA reductase inhibitors on skeletal muscles of rabbits by FUKAMI, M, MAEDA, N, FUKUSHIGE, J, KOGURE, Y, SHIMADA, Y, OGAWA, T, TSUJITA, Y

“…This study was undertaken to evaluate the potential of HMG-CoA reductase inhibitors, pravastatin sodium (hereafter abbreviated to pravastatin) and simvastatin,…”
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Tissue selectivity of pravastatin sodium, lovastatin and simvastatin by KOGA, Teiichiro, FUKUDA, Kuniaki, SHIMADA, Yohko, FUKAMI, Masaharu, KOIKE, Hiroyuki, TSUJITA, Yoshio

“…Tissue selectivity of pravastatin sodium (pravastatin), lovastatin and simvastatin, 3‐hydroxy‐3‐methylglutaryl‐CoA reductase inhibitors was examined by…”
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Cephalosporin antibiotics. II. Synthesis and biological properties of CS-461 and related compounds by Nakayama, E, Watanabe, K, Miyauchi, M, Fujimoto, K, Muramatsu, S, Yasuda, H, Fukami, M, Ide, J

“…The synthesis, structure-activity relationships, and biological properties of 3-thiazoliomethyl cephalosporins are described. 7-[2-(2-Aminothiazol-4-yl)-(Z)-2-…”
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Reduction of Serum Cholesterol Levels Alters Lesional Composition of Atherosclerotic Plaques: Effect of Pravastatin Sodium on Atherosclerosis in Mature WHHL Rabbits by Shiomi, Masashi, Ito, Takashi, Tsukada, Toyohiro, Yata, Tatsuo, Watanabe, Yoshio, Tsujita, Yoshio, Fukami, Masaharu, Fukushige, Jun-ichiro, Hosokawa, Tsunemichi, Tamura, Atsuhiro

“…We examined whether serum cholesterol reduction alters the lesional composition of atherosclerotic plaques. To reduce serum cholesterol levels, we gave…”
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The Mechanism of Comparable Serum Cholesterol Lowering Effects of Pravastatin Sodium, a 3-Hydroxy-3-Methylglutaryl Coenzyme A Inhibitor, between Once- and Twice-Daily Treatment Regimens in Beagle Dogs and Rabbits by Fujioka, Tomoyuki, Nara, Futoshi, Shimada, Yoko, Fukushige, Junichiro, Shimotsu, Hidenori, Shigehara, Eiji, Fukami, Masaharu, Tsujita, Yoshio

“…In dogs, no significant difference in the reduction of serum cholesterol was observed among three dosing regimens of pravastatin: once in the morning (3…”
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GENERAL SESSION by Aida, Takeo, Urata, Shinichi, AKIMOTO, Yoshihiro, OBINATA, Akiko, ODA, Yuko, ENDO, Hiroyoshi, KASAI, Ken-ichi, HIRANO, Hiroshi, AOKI, Toshihiro, OINUMA, Tsutomu, KAWANO, Junichi, SUGANUMA, Tatsuo, Arai, Ryohachi, Kojima, Yasuji, Arakawa, M., Mizoguchi, A., Fujimoto, E., Ide, C., TAKASHIMA, Yoichiro, OGAWA, Kazuo, ARAKI, Tsutomu, Ogawa, Y., Kuwahara, H., Yagi, T., CHIDA, Kohsuke, CHIKAMORI, Kensuke, CUI, Yong-xi, KIGUCHI, Kazushige, NOZAWA, Shirou, IWAMORI, Masao, NAGAI, Yoshitaka, KAWAKAMI, Hayato, DAIMON, T., KAWAI, K., UCHIDA, K., ASAYAMA, Kohtaro, SUZUKI, Koichi, KATO, Kiyohiko, KAWAOI, Akira, ENDO, Hisashi, NISHIMOTO, Hiroshi, TSUJI, Takao, NAKANE, Paul K., FUJII, Tetsuya, KOMORI, Kaoru, SAKAI, Masao, YAMADA, Keiki, KARASAWA, Nobuyuki, NAGATSU, Ikuko, FUJIMOTO, Toyoshi, FUKUDA, Kuniaki, FUKAMI, Masaharu, FUKUI, Makoto, KIMURA, Kumiko, QIAO, Yan, MURATA, Junzo, ASANO, Goro, HANAI, Toru, USUDA, Nobuteru, KONG, Yonuli, NAGATA, Tetsuji, HARADA, Takayuki, HASHIMOTO, Koichi, TORII, Ikuko, MORIKAWA, Shigeru, HAREYAMA, Masashi, HONDA, Yoshihito, KAWATA, Mitsuhiro, SHIMADA, Masahisa, TSUYAMA, S., NASHIO, N., MURATA, F., KATSUYAMA, T., IMAMOTO, Kikuko, NAGATU, Ikuko, Inada, K., Utunomiya, H., Sato, K., Osamura, R.Y., Katakami, H., Mayo, K., ISHIBASHI, Toshimitsu, KANAZAWA, Kyotaro, SAITO, Takuma, ITO, Nobuaki, KAWAHARA, Shingo, HIRANO, Yoshinari, HIROTA, Tadaomi, ITOH, Kinji, TAKESHITA, Tomoko, Watanabe, K., Itoh, Y., Angeletti, H., ITO-SAITO, Atsuko, MATSUMURA, Takeo, TANAKA, Chikako, IWAMOTO, Masunobu, WATANABE, Jun, ASADA-KUBOTA, Mari, KANAMURA, Shinsuke

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Effect of Captopril Treatment on Proteinuria in NZB/NZW F1 Hybrid Mice by KURAKATA, Shinichi, FUKAMI, Masaharu, KITAMURA, Kouichi

“…Oral treatment of female NZB/NZW F1 hybrid mice with captopril prevented the development of proteinuria and prolonged survival in mice demonstrating slight…”
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Effect of Captopril Treatment on Proteinuria in NZB/NZW F1 Hybrid Mice by KURAKATA, Shinichi, FUKAMI, Masaharu, KITAMURA, Kouichi

“…Oral treatment of female NZB/NZW F1 hybrid mice with captopril prevented the development of proteinuria and prolonged survival in mice demonstrating slight…”
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Troglitazone Prevents Chronic Pancreatitis and Diabetes in WBN/Kob Rats by Exerting Anti-inflammatory Effect by FUJIWARA, TOSHIHIKO, HORIUCHI, TOMOKO, OGAWA, JUNKO, FUKAMI, MASAHARU, HORIKOSHI, HIROYOSHI

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Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice by Fujiwara, T, Wada, M, Fukuda, K, Fukami, M, Yoshioka, S, Yoshioka, T, Horikoshi, H

“…Antidiabetic effects of CS-045 were evaluated in 5-month-old C57BL/KsJ-db/db mice (db/db). CS-045 administered for 3 weeks to diabetic db/db mice as a 0.2%…”
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Beneficial Renal Effects of CS-905, a Novel Dihydropyridine Calcium Blocker, in SHR by Oizumi, Kiyoshi, Nishino, Hiroshi, Miyamoto, Masaaki, Fukushige, Junichiro, Fukami, Masaharu, Koike, Hiroyuki

“…CS-905 is a potent dihydropyridine calcium blocker that has a gradual and long-lasting antihypertensive action with little tachycardia in SHR. In this study,…”
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Beneficial Renal Effects of CS-905, a Novel Dihydropyridine Calcium Blocker, in SHR by OIZUMI, Kiyoshi, NISHINO, Hiroshi, MIYAMOTO, Masaaki, FUKUSHIGE, Junichiro, FUKAMI, Masaharu, KOIKE, Hiroyuki

“…CS-905 is a potent dihydropyridine calcium blocker that has a gradual and long-lasting antihypertensive action with little tachycardia in SHR. In this study,…”
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Effects of Pravastatin Sodium Alone and in Combination with Cholestyramine on Hepatic, Intestinal and Adrenal Low Density Lipoprotein Receptors in Homozygous Watanabe Heritable Hyperlipidemic Rabbits by Kuroda, Masao, Matsumoto, Akiyo, Itakura, Hiroshige, Watanabe, Yoshio, Ito, Takashi, Shiomi, Masashi, Fukushige, Junichiro, Nara, Futoshi, Fukami, Masaharu, Tsujita, Yoshio

“…Pravastatin sodium (pravastatin), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, was administered alone (50 mg/kg) or in…”
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NEPHROPROTECTIVE EFFECT AND ITS MECHANISM OF BETAMIPRON (1): RELATIONSHIPS OF RENAL TRANSPORT by Naganuma, Hideo, Tokiwa, Hiroshi, Hirouchi, Yasukuni, Kawahara, Yukinori, Fukushige, Jun-ichiro, Fukami, Masaharu, Hirota, Koji, Muramatsu, Shigeki, Takahagi, Hidekuni, Inui, Ken-ichi, Tanigawara, Yusuke, Yasuhara, Masato, Hori, Ryohei, Kuwahara, Shogo

“…Nephroprotective effect of betamipron (BP) and its mechanism were investigated in view of renal transport of panipenem (PAPM), a new carbapenem antibiotic, in…”
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GENERAL PHARMACOLOGY OF CS-807 by KOBAYASHI, SHINSAKU, KAMIOKA, TOSHIHARU, KUMAKURA, SEIJI, FUKAMI, MASAHARU, IWATA, NOBUYOSHI, MORI, MASAHIRO, KAWAHARA, YUKINORI

“…We studied the pharmacology of CS-807 and R-3746, an active metabolite. Cefaclor was used as a reference compound. The doses of CS-807 administered, orally or…”
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Improvement of bioavailability of poorly absorbed drugs. III. Oral acute toxicity and local irritation of medium chain glyceride by Sekine, M, Maeda, E, Sasahara, K, Okada, R, Kimura, K, Fukami, M, Awazu, S

“…Oral acute toxicity of medium chain glyceride (MCG) was studied in mice and rats. In mice and rats, clinical signs such as irregular respiration, laxity of…”
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Effects of Pravastatin Sodium Alone and in Combination with Cholestyramine on Hepatic, Intestinal and Adrenal Low Density Lipoprotein Receptors in Homozygous Watanabe Heritable Hyperlipidemic Rabbits by Masao Kuroda, Akiyo Matsumoto, Hiroshige Itakura, Yoshio Watanabe, Takashi Ito, Masashi Shiomi, Junichiro Fukushige, Futoshi Nara, Masaharu Fukami, Yoshio Tsujita

“…Pravastatin sodium (pravastatin), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, was administered alone (50 mg/kg) or in…”
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Suppression of established atherosclerosis and xanthomas in mature WHHL rabbits by keeping their serum cholesterol levels extremely low. Effect of pravastatin sodium in combination with cholestyramine by Shiomi, M, Ito, T, Watanabe, Y, Tsujita, Y, Kuroda, M, Arai, M, Fukami, M, Fukushige, J, Tamura, A

“…We investigated the possibility that established atherosclerosis and xanthomas in mature WHHL rabbits could be suppressed or even regressed when their serum…”
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