Search Results - "FUKAI, N"

Lack of collagen XVIII/endostatin results in eye abnormalities by Fukai, Naomi, Eklund, Lauri, Marneros, Alexander G., Oh, Suk Paul, Keene, Douglas R., Tamarkin, Lawrence, Niemelä, Merja, Ilves, Mika, Li, En, Pihlajaniemi, Taina, Olsen, Bjorn R.

“…Mice lacking collagen XVIII and its proteolytically derived product endostatin show delayed regression of blood vessels in the vitreous along the surface of…”
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Matrilysin Cleavage of Corneal Collagen Type XVIII NC1 Domain and Generation of a 28-kDa Fragment by Lin, Hsin-Chiung, Chang, Jin-Hong, Jain, Sandeep, Gabison, Eric E, Kure, Tomoko, Kato, Takuji, Fukai, Naomi, Azar, Dimitri T

“…To localize endostatin and collagen type XVIII in human corneas and to characterize the enzymatic action of matrix metalloproteinases (MMPs) in the cleavage of…”
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Very early expression of vascular endothelial growth factor in brain oedema tissue associated with brain contusion by Suzuki, R, Fukai, N, Nagashijma, G, Asai, J I, Itokawa, H, Nagai, M, Suzuki, T, Fujimoto, T

“…Brain oedema associated with cerebral contusion can be life-threatening. Mechanisms of the development of brain oedema are still unclear. We investigated the…”
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Pork Barrel Politics, Networks, and Local Economic Development in Contemporary Japan by Fukui, Haruhiro, Fukai, Shigeko N.

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Mechanical force-induced midpalatal suture remodeling in mice by Hou, Bo, Fukai, Naomi, Olsen, Bjorn R

“…Abstract Mechanical stress is an important epigenetic factor for regulating skeletal remodeling, and application of force can lead to remodeling of both bone…”
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Japan in 1997: More Uncertain, Less Hopeful by Fukui, Haruhiro, Fukai, Shigeko N.

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Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye by Hopfer, Ulrike, Fukai, Naomi, Hopfer, Helmut, Wolf, Gunter, Joyce, Nancy, Li, En, Olsen, Bjorn R

“…Collagen VIII is localized in subendothelial and subepithelial extracellular matrices. It is a major component of Descemet's membrane, a thick basement…”
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Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth by O'Reilly, Michael S, Boehm, Thomas, Shing, Yuen, Fukai, Naomi, Vasios, George, Lane, William S, Flynn, Evelyn, Birkhead, James R, Olsen, Bjorn R, Folkman, Judah

“…We previously identified the angiogenesis inhibitor angiostatin. Using a similar strategy, we have identified endostatin, an angiogenesis inhibitor produced by…”
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Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney by Rossi, Maarit, Morita, Hiroyuki, Sormunen, Raija, Airenne, Sari, Kreivi, Marjut, Wang, Ling, Fukai, Naomi, Olsen, Bjorn R., Tryggvason, Karl, Soininen, Raija

“…Mice lacking exon 3 of perlecan (Hspg2) gene were generated by gene targeting. Exon deletion does not alter the expression or the reading frame but causes loss…”
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Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding by Yamaguchi, Noriko, Anand-Apte, Bela, Lee, Margaret, Sasaki, Takako, Fukai, Naomi, Shapiro, Robert, Que, Ivo, Lowik, Clemens, Timpl, Rupert, Olsen, Bjorn R.

“…Endostatin, produced as recombinant protein in human 293‐EBNA cells, inhibits the migration of human umbilical vein endothelial cells (HUVECs) in response to…”
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Aldosterone Induces Angiotensin Converting Enzyme Gene Expression via a JAK2-Dependent Pathway in Rat Endothelial Cells by Sugiyama, Toru, Yoshimoto, Takanobu, Tsuchiya, Kyoichiro, Gochou, Naoki, Hirono, Yuki, Tateno, Toru, Fukai, Nozomi, Shichiri, Masayoshi, Hirata, Yukio

“…Aldosterone is currently recognized as a risk hormone for cardiovascular disease. However, the cellular mechanism by which aldosterone acts on vasculature has…”
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Loss of collagen XVIII enhances neovascularization and vascular permeability in atherosclerosis by Moulton, Karen S, Olsen, Bjorn R, Sonn, Silvia, Fukai, Naomi, Zurakowski, David, Zeng, Xiaokun

“…Plaque neovascularization is thought to promote atherosclerosis; however, the mechanisms of its regulation are not understood. Collagen XVIII and its…”
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The polycystic kidney disease 1 ( Pkd1 ) gene is required for the responses of osteochondroprogenitor cells to midpalatal suture expansion in mice by Hou, Bo, Kolpakova-Hart, Elona, Fukai, Naomi, Wu, Kimberly, Olsen, Bjorn R

“…Abstract Mechanical stress is known to modulate postnatal skeletal growth and development. However, the mechanisms underlying the mechanotransduction are not…”
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Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism by Reichenberger, Ernst, Ueki, Yasuyoshi, Tiziani, Valdenize, Santanna, Carla, Fukai, Naomi, Maulik, Chris, Garfinkle, Judah, Ninomiya, Chisho, doAmaral, Cassio, Peters, Hartmut, Habal, Mutaz, Rhee-Morris, Laila, Doss, Jeffrey B, Kreiborg, Sven, Olsen, Bjorn R

“…Cherubism (MIM 118400) is an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws followed by…”
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Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin by Sasaki, Takako, Fukai, Naomi, Mann, Karlheinz, Göhring, Walter, Olsen, Björn R., Timpl, Rupert

“…The C‐terminal domain NC1 of mouse collagen XVIII (38 kDa) and the shorter mouse and human endostatins (22 kDa) were prepared in recombinant form from…”
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Characterization of endostatin binding to heparin and heparan sulfate by surface plasmon resonance and molecular modeling: role of divalent cations by Ricard-Blum, Sylvie, Féraud, Olivier, Lortat-Jacob, Hugues, Rencurosi, Anna, Fukai, Naomi, Dkhissi, Fatima, Vittet, Daniel, Imberty, Anne, Olsen, Bjorn R, van der Rest, Michel

“…Endostatin (20 kDa) is a C-terminal proteolytic fragment of collagen XVIII that is localized in vascular basement membrane zones in various organs. It binds…”
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Localization of Collagen XVIII and the Endostatin Portion of Collagen XVIII in Aged Human Control Eyes and Eyes with Age-Related Macular Degeneration by Bhutto, Imran A, Kim, Sahng Y, McLeod, D. Scott, Merges, Carol, Fukai, Naomi, Olsen, Bjorn R, Lutty, Gerard A

“…Endostatin, a C-terminal fragment of collagen XVIII (coll XVIII) formed by proteolysis, specifically inhibits endothelial cell migration and proliferation in…”
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Japan in 1996: Between Hope and Uncertainty by Fukui, Haruhiro, Fukai, Shigeko N.

“…Abstract only…”
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Urotensin II is an Autocrine/Paracrine Growth Factor for the Porcine Renal Epithelial Cell Line, LLCPK1 by Matsushita, Mika, Shichiri, Masayoshi, Fukai, Nozomi, Ozawa, Naoko, Yoshimoto, Takanobu, Takasu, Nobuyuki, Hirata, Yukio

“…Urotensin-II (UII), a cyclic dodecapeptide with potent cardiovascular effects, has recently been shown to be abundantly expressed in the human kidney and…”
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Migration and Growth Are Attenuated in Vascular Smooth Muscle Cells With Type VIII Collagen-Null Alleles by Adiguzel, Eser, Hou, Guangpei, Mulholland, Diane, Hopfer, Ulrike, Fukai, Naomi, Olsen, Bjorn, Bendeck, Michelle

“…OBJECTIVE—Type VIII collagen is upregulated after vascular injury and in atherosclerosis. However, the role of type VIII collagen endogenously expressed by…”
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