Search Results - "FUJISAWA, Shin"

Upregulation of microRNA-126-5p is associated with drug resistance to cytarabine and poor prognosis in AML patients by SHIBAYAMA, YOSHIHIKO, KONDO, TAKESHI, OHYA, HIROKI, FUJISAWA, SHIN-ICHI, TESHIMA, TAKANORI, ISEKI, KEN

“…MicroRNAs (miRs) have been shown to negatively regulate gene expression by binding to mRNAs, and they play an important role in various physiological processes…”
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Computed tomography-defined sarcopenia: prognostic predictor of nonrelapse mortality after allogeneic hematopoietic stem cell transplantation: a multicenter retrospective study by Ando, Taiki, Fujisawa, Shin, Teshigawara, Haruka, Matsumura, Ayako, Sakuma, Takayuki, Suzuki, Taisei, Teranaka, Hiroshi, Ogusa, Eriko, Ishii, Yoshimi, Miyashita, Kazuho, Takahashi, Hiroyuki, Nakajima, Yuki, Miyazaki, Takuya, Hagihara, Maki, Matsumoto, Kenji, Yamazaki, Etsuko, Nakajima, Hideaki

“…We analyzed clinical cutoffs for defining computed tomography (CT) methods for sarcopenia and examined the prognostic value of CT for allogeneic hematopoietic…”
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Compromised anti-tumor–immune features of myeloid cell components in chronic myeloid leukemia patients by Harada, Ibuki, Sasaki, Haruka, Murakami, Koichi, Nishiyama, Akira, Nakabayashi, Jun, Ichino, Motohide, Miyazaki, Takuya, Kumagai, Ken, Matsumoto, Kenji, Hagihara, Maki, Kawase, Wataru, Tachibana, Takayoshi, Tanaka, Masatsugu, Saito, Tomoyuki, Kanamori, Heiwa, Fujita, Hiroyuki, Fujisawa, Shin, Nakajima, Hideaki, Tamura, Tomohiko

“…Chronic myeloid leukemia (CML) is a form of myeloproliferative neoplasm caused by the oncogenic tyrosine kinase BCR-ABL. Although tyrosine kinase inhibitors…”
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Development and characterization of ten novel microsatellite loci for the emu (Dromaius novaehollandiae) and genetic diversity of Japanese farm populations by Koshiishi, Yuichi, Murata-Okubo, Michiko, Fujisawa, Shin-ichiro, Shimoi, Gaku, Hirayama, Hiroki, Kameyama, Yuichi, Souma, Kousaku, Wada, Kenta

“…The emu ( Dromaius novaehollandiae ) is a useful poultry animal farmed for fat, meat, and eggs. Genetic structure and relationships among farmed emu…”
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Current treatment of adult acute lymphoblastic leukemia by Fujisawa, Shin

“…The survival outcomes for children with acute lymphoblastic leukemia (ALL) have dramatically improved over recent years, and improved outcomes in adolescents…”
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Minimal residual disease (MRD) positivity at allogeneic hematopoietic cell transplantation, not the quantity of MRD, is a risk factor for relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia by Akahoshi, Yu, Arai, Yasuyuki, Nishiwaki, Satoshi, Mizuta, Shuichi, Marumo, Atsushi, Uchida, Naoyuki, Kanda, Yoshinobu, Sakai, Hitoshi, Takada, Satoru, Fukuda, Takahiro, Fujisawa, Shin, Ashida, Takashi, Tanaka, Junji, Atsuta, Yoshiko, Kako, Shinichi

“…Minimal residual disease (MRD) monitoring by quantitative real-time reverse transcription PCR (qRT-PCR) is the standard of care in Philadelphia…”
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Phase 2 study of bosutinib in Japanese patients with newly diagnosed chronic phase chronic myeloid leukemia by Hino, Masayuki, Matsumura, Itaru, Fujisawa, Shin, Ishizawa, Kenichi, Ono, Takaaki, Sakaida, Emiko, Sekiguchi, Naohiro, Tanetsugu, Yusuke, Fukuhara, Kei, Ohkura, Masayuki, Koide, Yuichiro, Takahashi, Naoto

“…This open-label, single-arm, phase 2 study (ClinicalTrials.gov, NCT03128411) evaluated the efficacy, safety, and pharmacokinetics of bosutinib at a starting…”
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Echocardiographic Findings of Malignant Lymphoma with Cardiac Involvement: A Single-center Retrospective Observational Study by Ebina, Toshiaki, Sano, Yuka, Hirabayashi, Michiko, Tsurumi, Tomomi, Watanabe, Mika, Furukawa, Mio, Matsuo, Wakana, Nagasawa, Hazuki, Hirose, Haruka, Horii, Mutsuo, Nakajima, Yuki, Fujisawa, Shin, Iwahashi, Noriaki, Hibi, Kiyoshi

“…Objective Although malignant lymphoma (ML) can occur in every organ, diagnosing cardiac involvement without cardiac manifestations is difficult. We therefore…”
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Prognostic value of measurable residual disease at allogeneic transplantation for adults with core binding factor acute myeloid leukemia in complete remission by Konuma, Takaaki, Kondo, Tadakazu, Masuko, Masayoshi, Shimizu, Hiroaki, Shiratori, Souichi, Fukuda, Takahiro, Kato, Jun, Sawa, Masashi, Ozawa, Yukiyasu, Ota, Shuichi, Uchida, Naoyuki, Kanda, Yoshinobu, Kako, Shinichi, Fujisawa, Shin, Fukushima, Kentaro, Ichinohe, Tatsuo, Atsuta, Yoshiko, Yanada, Masamitsu

“…Pretransplant measurable residual disease (MRD) has been shown to be associated with relapse incidence following allogeneic hematopoietic cell transplantation…”
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Successful Pregnancy and Delivery After Frozen-thawed Embryo Transfer Following the Third Discontinuation of Tyrosine Kinase Inhibitor in a Woman with Chronic Myeloid Leukemia by Takayama, Kosuke, Fujisawa, Shin, Sakuma, Takayuki, Hasegawa, Kodai, Katsuki, Kengo, Akimoto, Masahiro, Matsumura, Ayako, Nakajima, Yuki, Miyazaki, Takuya, Murase, Mariko, Nakajima, Hideaki

“…Assisted reproductive technology is a viable option for pregnant women with chronic myeloid leukemia. We herein report the case of a patient who underwent…”
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Bosutinib in Japanese patients with newly diagnosed chronic-phase chronic myeloid leukemia: final 3-year follow-up results of a phase 2 study by Ono, Takaaki, Hino, Masayuki, Matsumura, Itaru, Fujisawa, Shin, Ishizawa, Kenichi, Sakaida, Emiko, Sekiguchi, Naohiro, Ono, Chiho, Aizawa, Mana, Tanetsugu, Yusuke, Koide, Yuichiro, Takahashi, Naoto

“…Bosutinib has been evaluated for treatment of chronic-phase chronic myeloid leukemia (CP-CML) in several clinical studies, including in Japan. This open-label,…”
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A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study by Miyawaki, Shuichi, Ohtake, Shigeki, Fujisawa, Shin, Kiyoi, Hitoshi, Shinagawa, Katsuji, Usui, Noriko, Sakura, Toru, Miyamura, Koichi, Nakaseko, Chiaki, Miyazaki, Yasushi, Fujieda, Atsushi, Nagai, Tadashi, Yamane, Takahisa, Taniwaki, Masafumi, Takahashi, Masatomo, Yagasaki, Fumiharu, Kimura, Yukihiko, Asou, Norio, Sakamaki, Hisashi, Handa, Hiroshi, Honda, Sumihisa, Ohnishi, Kazunori, Naoe, Tomoki, Ohno, Ryuzo

“…We conducted a prospective randomized study to assess the optimal postremission therapy for adult acute myeloid leukemia in patients younger than 65 years in…”
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Impact of bone marrow nucleated cell subfractions on transplant outcomes in patients with acute lymphoblastic leukemia by Nukui, Jun, Tachibana, Takayoshi, Miyazaki, Takuya, Tanaka, Masatsugu, Matsumoto, Kenji, Ishii, Yoshimi, Numata, Ayumi, Nakajima, Yuki, Matsumura, Ayako, Suzuki, Taisei, Izumi, Akihiko, Hirose, Natsuki, Yamamoto, Koji, Hagihara, Maki, Fujisawa, Shin, Nakajima, Hideaki

“…Our previous study showed that a high pre-transplant nucleated cell count in the bone marrow is associated with increased non-relapse mortality (NRM) and…”
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Hematopoietic Stem Cell Transplantation From a Related Donor with Human Leukocyte Antigen 1-Antigen Mismatch in the Graft-Versus-Host Direction Using Low-dose Anti-thymocyte Globulin by Kanda, Junya, Ando, Toshihiko, Kimura, Shun-ichi, Fujiwara, Shin-ichiro, Imada, Kazunori, Fujisawa, Shin, Tachibana, Takayoshi, Atsuta, Yoshiko, Kanda, Yoshinobu

“…Hematopoietic stem cell transplantation (HSCT) from a related donor with an human leukocyte antigen (HLA) 1-antigen mismatch without in vivo T cell depletion…”
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Mitochondrial DNA variations in Japanese farmed emu populations by KOSHIISHI, Yuichi, UKITA, Misuzu, MURATA-OKUBO, Michiko, FUJISAWA, Shin-ichiro, SHIMOI, Gaku, HIRAYAMA, Hiroki, KAMEYAMA, Yuichi, SOUMA, Kousaku, WADA, Kenta

“…The emu (Dromaius novaehollandiae) is a new poultry. In this study, we investigated the haplotype composition of mitochondrial DNA among emu populations farmed…”
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Prognostic index for patients with relapsed or refractory acute myeloid leukemia who underwent hematopoietic cell transplantation: a KSGCT multicenter analysis by Tachibana, Takayoshi, Kanda, Junya, Ishizaki, Takuma, Najima, Yuho, Tanaka, Masatsugu, Doki, Noriko, Fujiwara, Shin-ichiro, Kimura, Shun-ichi, Onizuka, Makoto, Takahashi, Satoshi, Saito, Takeshi, Mori, Takehiko, Fujisawa, Shin, Sakaida, Emiko, Matsumoto, Kenji, Aotsuka, Nobuyuki, Goto, Moritaka, Watanabe, Reiko, Shono, Katsuhiro, Usuki, Kensuke, Tsukada, Nobuhiro, Kanamori, Heiwa, Kanda, Yoshinobu, Okamoto, Shinichiro

“…A multicenter retrospective study was performed to explore a prognostic scoring index in order to identify a population who are least likely to benefit from…”
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Stopping tyrosine kinase inhibitors started after allogeneic HCT in patients with Philadelphia chromosome-positive leukemia by Nakasone, Hideki, Kako, Shinichi, Mori, Takehiko, Takahashi, Satoshi, Onizuka, Makoto, Fujiwara, Shin-ichiro, Sakura, Toru, Sakaida, Emiko, Yokota, Akira, Aotsuka, Nobuyuki, Hagihara, Maki, Tsukada, Nobuhiro, Hatta, Yoshihiro, Usuki, Kensuke, Watanabe, Reiko, Gotoh, Moritaka, Fujisawa, Shin, Yano, Shingo, Kanamori, Heiwa, Okamoto, Shinichiro, Kanda, Yoshinobu

“…For patients with Philadelphia chromosome (Ph)-positive leukemia, there is no consensus regarding how long tyrosine kinase inhibitors (TKI) should be given or…”
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Impact of treatment-related weight changes from diagnosis to hematopoietic stem-cell transplantation on clinical outcome of acute myeloid leukemia by Ando, Taiki, Fujisawa, Shin, Teshigawara, Haruka, Ogusa, Eriko, Ishii, Yoshimi, Miyashita, Kazuho, Motohashi, Kenji, Miyazaki, Takuya, Tachibana, Takayoshi, Hagihara, Maki, Matsumoto, Kenji, Tanaka, Masatsugu, Hashimoto, Chizuko, Koharazawa, Hideyuki, Fujimaki, Katsumichi, Taguchi, Jun, Fujita, Hiroyuki, Kanamori, Heiwa, Yamazaki, Etsuko, Nakajima, Hideaki

“…We hypothesized that treatment-related weight loss is associated with worse outcomes following HSCT. Overall, 184 patients with AML who underwent induction…”
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Phase 2 study of arsenic trioxide followed by autologous hematopoietic cell transplantation for relapsed acute promyelocytic leukemia by Yanada, Masamitsu, Tsuzuki, Motohiro, Fujita, Hiroyuki, Fujimaki, Katsumichi, Fujisawa, Shin, Sunami, Kazutaka, Taniwaki, Masafumi, Ohwada, Akira, Tsuboi, Kosuke, Maeda, Akio, Takeshita, Akihiro, Ohtake, Shigeki, Miyazaki, Yasushi, Atsuta, Yoshiko, Kobayashi, Yukio, Naoe, Tomoki, Emi, Nobuhiko

“…The optimal treatments for relapsed acute promyelocytic leukemia (APL) remain equivocal. We conducted a phase 2 study to evaluate the efficacy and feasibility…”
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Dasatinib versus imatinib in Japanese patients with newly diagnosed chronic phase chronic myeloid leukemia: a subanalysis of the DASISION 5-year final report by Nakamae, Hirohisa, Fujisawa, Shin, Ogura, Michinori, Uchida, Toshiki, Onishi, Yasushi, Taniwaki, Masafumi, Utsunomiya, Atae, Matsue, Kosei, Takamatsu, Yasushi, Usuki, Kensuke, Tanimoto, Mitsune, Ishida, Yoji, Ohashi, Kazuteru, Li, Li, Miyoshi, Masafumi

“…The international phase III DASISION trial demonstrated improved efficacy of dasatinib versus imatinib in treatment-naive patients with chronic myeloid…”
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