Search Results - "FUJISAKA, SHIHO"

The role of adipose tissue M1/M2 macrophages in type 2 diabetes mellitus by Fujisaka, Shiho

“…Obesity and insulin resistance are closely associated with a state of low-grade inflammation in the body, and adipose tissue macrophages (ATMs) play central…”
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The gut microbiome: a core regulator of metabolism by Fujisaka, Shiho, Watanabe, Yoshiyuki, Tobe, Kazuyuki

“…The human body is inhabited by numerous bacteria, fungi, and viruses, and each part has a unique microbial community structure. The gastrointestinal tract…”
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Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome by Ussar, Siegfried, Griffin, Nicholas W., Bezy, Olivier, Fujisaka, Shiho, Vienberg, Sara, Softic, Samir, Deng, Luxue, Bry, Lynn, Gordon, Jeffrey I., Kahn, C. Ronald

“…Obesity, diabetes, and metabolic syndrome result from complex interactions between genetic and environmental factors, including the gut microbiota. To dissect…”
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Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism by Soto, Marion, Herzog, Clémence, Pacheco, Julian A., Fujisaka, Shiho, Bullock, Kevin, Clish, Clary B., Kahn, C. Ronald

“…Obesity and diabetes in humans are associated with increased rates of anxiety and depression. To understand the role of the gut microbiome and brain insulin…”
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Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome by Ussar, Siegfried, Fujisaka, Shiho, Kahn, C. Ronald

“…Abstract Background Diabetes, obesity, and the metabolic syndrome are multifactorial diseases dependent on a complex interaction of host genetics, diet, and…”
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Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites by Fujisaka, Shiho, Avila-Pacheco, Julian, Soto, Marion, Kostic, Aleksandar, Dreyfuss, Jonathan M., Pan, Hui, Ussar, Siegfried, Altindis, Emrah, Li, Ning, Bry, Lynn, Clish, Clary B., Kahn, C. Ronald

“…Diet, genetics, and the gut microbiome are determinants of metabolic status, in part through production of metabolites by the gut microbiota. To understand the…”
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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling by Softic, Samir, Gupta, Manoj K, Wang, Guo-Xiao, Fujisaka, Shiho, O'Neill, Brian T, Rao, Tata Nageswara, Willoughby, Jennifer, Harbison, Carole, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B, Cohen, David E, Kahn, C Ronald

“…Overconsumption of high-fat diet (HFD) and sugar-sweetened beverages are risk factors for developing obesity, insulin resistance, and fatty liver disease. Here…”
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Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins by Softic, Samir, Meyer, Jesse G, Wang, Guo-Xiao, Gupta, Manoj K, Batista, Thiago M, Lauritzen, Hans P M M, Fujisaka, Shiho, Serra, Dolors, Herrero, Laura, Willoughby, Jennifer, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B, Gibson, Bradford W, Schilling, Birgit, Cohen, David E, Kahn, C Ronald

“…Dietary sugars, fructose and glucose, promote hepatic de novo lipogenesis and modify the effects of a high-fat diet (HFD) on the development of insulin…”
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Antibiotic effects on gut microbiota and metabolism are host dependent by Fujisaka, Shiho, Ussar, Siegfried, Clish, Clary, Devkota, Suzanne, Dreyfuss, Jonathan M, Sakaguchi, Masaji, Soto, Marion, Konishi, Masahiro, Softic, Samir, Altindis, Emrah, Li, Ning, Gerber, Georg, Bry, Lynn, Kahn, C Ronald

“…Interactions of diet, gut microbiota, and host genetics play important roles in the development of obesity and insulin resistance. Here, we have investigated…”
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Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice by FUJISAKA, Shiho, USUI, Isao, KOBAYASHI, Masashi, TOBE, Kazuyuki, BUKHARI, Agussalim, IKUTANI, Masashi, OYA, Takeshi, KANATANI, Yukiko, TSUNEYAMA, Koichi, NAGAI, Yoshinori, TAKATSU, Kiyoshi, URAKAZE, Masaharu

“…Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice Shiho Fujisaka 1 , Isao Usui 1 , Agussalim Bukhari 1 , Masashi…”
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CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors by Nawaz, Allah, Aminuddin, Aminuddin, Kado, Tomonobu, Takikawa, Akiko, Yamamoto, Seiji, Tsuneyama, Koichi, Igarashi, Yoshiko, Ikutani, Masashi, Nishida, Yasuhiro, Nagai, Yoshinori, Takatsu, Kiyoshi, Imura, Johji, Sasahara, Masakiyo, Okazaki, Yukiko, Ueki, Kohjiro, Okamura, Tadashi, Tokuyama, Kumpei, Ando, Akira, Matsumoto, Michihiro, Mori, Hisashi, Nakagawa, Takashi, Kobayashi, Norihiko, Saeki, Kumiko, Usui, Isao, Fujisaka, Shiho, Tobe, Kazuyuki

“…Adipose tissue resident macrophages have important roles in the maintenance of tissue homeostasis and regulate insulin sensitivity for example by secreting…”
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Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity by Fujisaka, Shiho, Usui, Isao, Nawaz, Allah, Igarashi, Yoshiko, Okabe, Keisuke, Furusawa, Yukihiro, Watanabe, Shiro, Yamamoto, Seiji, Sasahara, Masakiyo, Watanabe, Yoshiyuki, Nagai, Yoshinori, Yagi, Kunimasa, Nakagawa, Takashi, Tobe, Kazuyuki

“…Obesity and insulin resistance are associated with dysbiosis of the gut microbiota and impaired intestinal barrier function. Herein, we report that…”
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Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD by Softic, Samir, Boucher, Jeremie, Solheim, Marie H, Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P, Winnay, Jonathon, Perez-Atayde, Antonio R, Kahn, C Ronald

“…Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of…”
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Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway by Nishida, Yasuhiro, Nawaz, Allah, Kado, Tomonobu, Takikawa, Akiko, Igarashi, Yoshiko, Onogi, Yasuhiro, Wada, Tsutomu, Sasaoka, Toshiyasu, Yamamoto, Seiji, Sasahara, Masakiyo, Imura, Johji, Tokuyama, Kumpei, Usui, Isao, Nakagawa, Takashi, Fujisaka, Shiho, Kunimasa, Yagi, Tobe, Kazuyuki

“…Background Skeletal muscle is mainly responsible for insulin‐stimulated glucose disposal. Dysfunction in skeletal muscle metabolism especially during obesity…”
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Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration by Nawaz, Allah, Bilal, Muhammad, Fujisaka, Shiho, Kado, Tomonobu, Aslam, Muhammad Rahil, Ahmed, Saeed, Okabe, Keisuke, Igarashi, Yoshiko, Watanabe, Yoshiyuki, Kuwano, Takahide, Tsuneyama, Koichi, Nishimura, Ayumi, Nishida, Yasuhiro, Yamamoto, Seiji, Sasahara, Masakiyo, Imura, Johji, Mori, Hisashi, Matzuk, Martin M., Kudo, Fujimi, Manabe, Ichiro, Uezumi, Akiyoshi, Nakagawa, Takashi, Oishi, Yumiko, Tobe, Kazuyuki

“…Muscle regeneration requires the coordination of muscle stem cells, mesenchymal fibro-adipogenic progenitors (FAPs), and macrophages. How macrophages regulate…”
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In Vivo Depletion of CD206+ M2 Macrophages Exaggerates Lung Injury in Endotoxemic Mice by Kambara, Kenta, Ohashi, Wakana, Tomita, Kengo, Takashina, Michinori, Fujisaka, Shiho, Hayashi, Ryuji, Mori, Hisashi, Tobe, Kazuyuki, Hattori, Yuichi

“…Although phenotypically polarized macrophages are now generally classified into two major subtypes termed proinflammatory M1 and anti-inflammatory M2…”
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A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid Watasenia scintillans by Ishimoto, Tetsuya, Okada, Takuya, Fujisaka, Shiho, Yagi, Kunimasa, Tobe, Kazuyuki, Toyooka, Naoki, Mori, Hisashi

“…This study demonstrates that the luciferin of the firefly squid Watasenia scintillans, which generally reacts with Watasenia luciferase, reacted with human…”
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Isoliquiritigenin Attenuates Adipose Tissue Inflammation and Metabolic Syndrome by Modifying Gut Bacteria Composition in Mice by Ishibashi, Riko, Furusawa, Yukihiro, Honda, Hiroe, Watanabe, Yasuharu, Fujisaka, Shiho, Nishikawa, Miyu, Ikushiro, Shinichi, Kurihara, Shin, Tabuchi, Yoshiaki, Tobe, Kazuyuki, Takatsu, Kiyoshi, Nagai, Yoshinori

“…Scope Isoliquiritigenin (ILG) has been reported to attenuate adipose tissue inflammation and metabolic disorder; however, the underlying mechanisms remain to…”
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Gut Microbiota Regulate Pancreatic Growth, Exocrine Function, and Gut Hormones by Girdhar, Khyati, Soto, Marion, Huang, Qian, Orliaguet, Lucie, Cederquist, Carly, Sundaresh, Bharathi, Hu, Jiang, Figura, Maximilian, Raisingani, Amol, Canfora, Emanuel E, Dirice, Ercument, Fujisaka, Shiho, Goossens, Gijs H, Blaak, Ellen E, Kulkarni, Rohit N, Kahn, C Ronald, Altindis, Emrah

“…Growing evidence indicates an important link between gut microbiota, obesity, and metabolic syndrome. Alterations in exocrine pancreatic function are also…”
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Heterogeneity of adipose tissue-resident macrophages-beyond M1/M2 paradigm by Nawaz, Allah, Fujisaka, Shiho, Kado, Tomonobu, Jeelani, Ishtiaq, Tobe, Kazuyuki

“…Adipose tissue-resident macrophages (ATMs) are reported to be important for maintaining adipose tissue remodeling and homeostasis. ATMs were classified for the…”
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