Search Results - "FUJINO, MASAYUKI"
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Nephritis-Associated Plasmin Receptor (NAPlr): An Essential Inducer of C3-Dominant Glomerular Injury and a Potential Key Diagnostic Biomarker of Infection-Related Glomerulonephritis (IRGN)
Published in International journal of molecular sciences (01-09-2022)“…Nephritis-associated plasmin receptor (NAPlr) was originally isolated from the cytoplasmic fraction of group A Streptococci, and was found to be the same…”
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C-reactive Protein Can Predict Patients with Cirrhosis at a High Risk of Early Mortality after Acute Esophageal Variceal Bleeding
Published in Internal Medicine (15-02-2019)“…Objective The aim of this study was to identify patients with a high risk of early mortality after acute esophageal variceal bleeding by measuring the…”
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Oxidative Stress in Hypoxic-Ischemic Encephalopathy: Molecular Mechanisms and Therapeutic Strategies
Published in International journal of molecular sciences (10-12-2016)“…Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of morbidity and mortality in neonates. Because of high concentrations of sensitive immature…”
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Protective role of heme oxygenase-1 in fatty liver ischemia–reperfusion injury
Published in Medical molecular morphology (01-06-2019)“…Ischemia–reperfusion (IR) injury is a kind of injury resulting from the restoration of the blood supply after blood vessel closure during liver transplantation…”
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Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice
Published in PloS one (09-11-2017)“…Steatosis has a low tolerance against ischemia-reperfusion injury (IRI). To prevent IRI in the steatotic liver, we attempted to elucidate the protective effect…”
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Targeted immune cell therapy for hepatocellular carcinoma using expanded liver mononuclear cell-derived natural killer cells
Published in Neoplasia (New York, N.Y.) (01-12-2024)“…•LMNC-NK cells demonstrate enhanced anti-tumor efficacy.•LMNCs exhibit a distinct gene expression profile.•LMNC-derived NK cells from liver perfusate offer…”
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Supervised machine learning of outbred mouse genotypes to predict hepatic immunological tolerance of individuals
Published in Scientific reports (17-10-2024)“…It is essential to elucidate the molecular mechanisms underlying liver transplant tolerance and rejection. In cases of mouse liver transplantation between…”
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Coral calcium carried hydrogen ameliorates the severity of non-alcoholic steatohepatitis induced by a choline deficient high carbohydrate fat-free diet in elderly rats
Published in Scientific reports (19-07-2023)“…Hydrogen has been reported to act as an antioxidant, anti-apoptosis and anti-inflammatory agent. Coral calcium carried hydrogen (G2-SUISO) is a safer and more…”
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Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes
Published in Scientific reports (30-06-2014)“…Hydrogen exerts beneficial effects in disease animal models of ischemia-reperfusion injury as well as inflammatory and neurological disease. Additionally,…”
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Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling
Published in American journal of physiology: Gastrointestinal and liver physiology (01-04-2021)“…Nonalcoholic steatohepatitis (NASH) could progress to hepatic fibrosis in the absence of effective control. The purpose of our experiment was to investigate…”
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Prolonged Cold Ischemia Time in Mouse Heart Transplantation Using Supercooling Preservation
Published in Transplantation (01-09-2020)“…BACKGROUND.Supercooling preservation techniques store a donor organ below 0°C without freezing. This has great advantages in inhibiting metabolism and…”
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Combined phospholipids adjuvant augments anti-tumor immune responses through activated tumor-associated dendritic cells
Published in Neoplasia (New York, N.Y.) (01-05-2023)“…•cPLs augments the anti-tumor immune responses.•cPLs changes the phenotype of TADCs from suppressive to promotive.•cPLs enhances the production of cytokine in…”
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Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression
Published in Scientific reports (19-09-2018)“…Fatty liver has lower tolerance against ischemia-reperfusion (I/R) injury in liver operations, including liver transplantation. Seeking to ameliorate liver…”
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Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats
Published in Oxidative medicine and cellular longevity (2020)“…Neonatal hypoxic-ischemic encephalopathy (HIE) is a leading cause of death in neonates with no effective treatments. Recent advancements in hydrogen (H2) gas…”
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Hydrogen inhalation protects hypoxic–ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats
Published in Experimental biology and medicine (Maywood, N.J.) (01-09-2019)“…Hypoxic–ischemic brain damage (HIBD) is one of the leading causes of brain injury in infant with high risk of mortality and disability; therefore, it is…”
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Development of Small-Molecule Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins
Published in Chemical & pharmaceutical bulletin (01-01-2024)“…The capsid of human immunodeficiency virus type 1 (HIV-1) forms a conical structure by assembling oligomers of capsid (CA) proteins and is a virion shell that…”
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Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins
Published in RSC advances (06-01-2023)“…The HIV-1 capsid is a shell that encapsulates viral RNA, and forms a conical structure by assembling oligomers of capsid (CA) proteins. Since the CA proteins…”
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Early Prediction of the Outcome Using Tumor Markers and mRECIST in Unresectable Hepatocellular Carcinoma Patients Who Underwent Transarterial Chemoembolization
Published in Oncology (01-01-2016)“…We examined early predictors of the outcome in hepatocellular carcinoma (HCC) patients after transarterial chemoembolization (TACE). We analyzed 116 patients…”
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Dimeric C34 Derivatives Linked through Disulfide Bridges as New HIV‐1 Fusion Inhibitors
Published in Chembiochem : a European journal of chemical biology (16-08-2019)“…C34, a 34‐mer fragment peptide, is contained in the HIV‐1 envelope protein gp41. A dimeric derivative of C34 linked through a disulfide bridge at its C…”
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